Reds Secure Victory Over Cubs in Close Matchup
Sunday, September 21, 2025, 1:40 PM ET · Great American Ball Park
Cincinnati Reds 1, Chicago Cubs 0, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.
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Quick answers
Who won Chicago Cubs vs Cincinnati Reds?
Cincinnati Reds beat Chicago Cubs 1-0 at Great American Ball Park on September 21, 2025.
In a tightly contested game at Great American Ball Park, the Cincinnati Reds edged out the Chicago Cubs with a final score of 1-0. The victory marked a significant moment for the Reds, who have been on a strong run, winning their last four games and showcasing an impressive home record of 3-0 in their last three home outings. This win also allowed the Reds to clinch the series against the Cubs with a 5-2 record in their meetings this season.
The Reds have been in solid form, boasting a 7-3 record over their last ten games. They have averaged 4.2 runs scored per game while allowing only 3.5 runs, indicating a well-balanced performance. Their recent success includes victories over the Cubs in the previous three games leading up to this matchup, with scores of 6-3, 7-4, and 1-0, all at home. The Reds' strong home performance has contributed to their overall record of 80-76 this season.
On the other hand, the Chicago Cubs have struggled recently, losing their last three games and holding a 6-4 record over their last ten. They have averaged 4.0 runs scored per game but allowed 3.3 runs, which reflects a competitive but faltering performance. The Cubs' away record stands at 4-3 in their last ten games, contributing to an overall record of 88-68 this season.
In terms of injuries, the Reds are dealing with several key players on the injured list, including Graham Ashcraft, who is on the 60-Day Injured List due to an elbow issue, and Eugenio Suarez, who is day-to-day for personal reasons. Additionally, Ke'Bryan Hayes, Spencer Steer, and Michael Toglia are all on the 10-Day Injured List for various injuries. The Cubs also have notable absences, with Edward Cabrera on the 15-Day Injured List due to a finger injury and Shelby Miller on the 60-Day Injured List with an elbow issue. Jacob Webb and Pedro Ramirez are both day-to-day with arm and back injuries, respectively, while Gavin Hollowell is on the 15-Day Injured List due to a shoulder problem.
The market had priced the Reds' chances favorably, reflecting their recent form and home advantage. The odds indicated a strong probability of a Reds win, which they fulfilled with this narrow victory.
The game was characterized by a pivotal scoring play in the third inning when Lux doubled to right field, allowing McLain to score the only run of the game. This moment proved crucial, as the Reds' pitching staff held the Cubs scoreless throughout the game, emphasizing their defensive capabilities.
As the season progresses, the Reds will look to maintain their momentum, while the Cubs will need to regroup and address their recent struggles to secure a strong finish to the season.
Injury report
- Graham Ashcraft60-Day-ILElbowCincinnati Reds
- Eugenio SuarezDay-To-DayPersonalCincinnati Reds
- Ke'Bryan Hayes10-Day-ILGroinCincinnati Reds
- Spencer Steer10-Day-ILWristCincinnati Reds
- Michael Toglia10-Day-ILShoulderCincinnati Reds
- Edward Cabrera15-Day-ILFingerChicago Cubs
- Shelby Miller60-Day-ILElbowChicago Cubs
- Jacob WebbDay-To-DayArmChicago Cubs
- Pedro RamirezDay-To-DayBackChicago Cubs
- Gavin Hollowell15-Day-ILShoulderChicago Cubs
Recent form
Cincinnati Reds
Last 10: 7-3Streak W44.2 scored · 3.5 allowed per game3-0 at home
- W6-3vs Chicago CubsSep 20
- W7-4vs Chicago CubsSep 19
- W1-0vs Chicago CubsSep 18
- W6-2at St. Louis CardinalsSep 17
- L0-3at St. Louis CardinalsSep 16
- W11-6at St. Louis CardinalsSep 15
- L5-11at AthleticsSep 14
- L0-3at AthleticsSep 13
- W2-1at San Diego PadresSep 11
- W4-2at San Diego PadresSep 10
Chicago Cubs
Last 10: 6-4Streak L34 scored · 3.3 allowed per game4-3 away
- L3-6at Cincinnati RedsSep 20
- L4-7at Cincinnati RedsSep 19
- L0-1at Cincinnati RedsSep 18
- W8-4at Pittsburgh PiratesSep 17
- W4-1at Pittsburgh PiratesSep 16
- W4-0at Pittsburgh PiratesSep 15
- W4-3vs Tampa Bay RaysSep 14
- L4-5vs Tampa Bay RaysSep 13
- W6-4vs Tampa Bay RaysSep 12
- W3-2at Atlanta BravesSep 10
Standings
| Team | Games behind | Lost | Streak | Win % | Won |
|---|---|---|---|---|---|
| Milwaukee | - | 53 | W2 | .621 | 87 |
| Chicago | 9 | 62 | L2 | .557 | 78 |
| St. Louis | 17 | 70 | W2 | .500 | 70 |
| Pittsburgh | 19 | 72 | L1 | .486 | 68 |
| Cincinnati | 20 | 73 | W2 | .479 | 67 |
How the scoring went
- 3rd Inning0-1Lux doubled to right, McLain scored.
Win probability
Above the line favours Cincinnati Reds, below favours Chicago Cubs.
Venue
- Great American Ball ParkCincinnati, Ohio
- Attendance29661
- OfficialsBrian Walsh, Edwin Moscoso, Chad Whitson, David Rackley
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- Schlittler sharp, the Yankees score 5 2-out runs in the 10th in a 6-3 win over the Angels
- New York Yankees vs. Los Angeles Angels: Game Highlights
Picks for MLB
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These two, other days
- Cubs Dominate Reds in 9-1 Victory at Great American Ball ParkSep 20, 2026
- Cubs Defeat Reds 5-2 at Great American Ball ParkSep 19, 2026
- Reds Edge Cubs in Thrilling Contest at Great American Ball ParkSep 18, 2026
- Cincinnati Reds Edge Chicago Cubs in Thrilling FinishAug 30, 2026
- Cubs Dominate Reds in High-Scoring Finale at Wrigley FieldAug 29, 2026