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MLB · Final

Cubs Edge Padres in Close Contest at Petco Park

Wednesday, April 29, 2026, 4:10 PM ET · Petco Park

Chicago Cubs 5, San Diego Padres 4, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Chicago Cubs vs San Diego Padres?

Chicago Cubs beat San Diego Padres 5-4 at Petco Park on April 29, 2026.

Who was favored in Chicago Cubs vs San Diego Padres?

San Diego Padres were the favorite at DraftKings, moneyline -115 (about 53% implied). The underdog won.

In a thrilling matchup at Petco Park, the Chicago Cubs narrowly defeated the San Diego Padres with a final score of 5-4. This victory allowed the Cubs to win the series 2-1 against the Padres, showcasing their competitive edge in this closely contested series.

The Cubs entered the game with an away record of 19-12 and had been on a strong run, boasting an overall record of 8-2 in their last ten games, although they faced a two-game losing streak leading into this matchup. Their average runs scored during this stretch was 5.8, while they allowed an average of 4.0 runs per game. In contrast, the Padres had a home record of 19-11 and were 7-3 in their last ten games, with an average of 4.6 runs scored and 4.9 runs allowed per game. The Padres had just come off a win against the Cubs the previous day, where they triumphed 9-7.

In terms of home and away performance, the Padres maintained a strong home record of 4-0 in their last four games at Petco Park, while the Cubs had struggled slightly on the road, recording a 1-2 record in their last three away games. This context added to the anticipation surrounding the game, as both teams were looking to capitalize on their recent performances.

The matchup was also notable for its injury implications. The Padres were missing several key players, including Jason Adam (60-Day IL, shoulder), Miguel Andujar (10-Day IL, wrist), Gavin Sheets (10-Day IL, foot), Jeremiah Estrada (15-Day IL, shoulder), and Lucas Giolito (60-Day IL, elbow). The Cubs also faced challenges with injuries, having Edward Cabrera (15-Day IL, finger), Shelby Miller (60-Day IL, elbow), and Gavin Hollowell (15-Day IL, shoulder) on the injured list, while Jacob Webb and Pedro Ramirez were listed as day-to-day.

As the game unfolded, the Cubs struck first in the second inning when Amaya singled to center, allowing Conforto to score. The Cubs continued to build their lead in the fourth inning with a two-run homer from Crow-Armstrong, which brought Shaw home as well, making the score 3-0. The Padres responded in the fifth inning with a homer from Andujar, cutting the deficit to 3-1, and Castellanos later tied the game with a two-run homer, bringing the score to 3-3.

However, the Cubs regained the lead in the sixth inning when Crow-Armstrong grounded out to first, allowing Conforto to score. Shaw added to the Cubs' lead with another homer in the eighth inning, making it 5-3. The Padres made a late push in the eighth inning with a sacrifice fly from Tatis Jr., which scored Castellanos, narrowing the gap to 5-4. Despite their efforts, the Padres were unable to complete the comeback.

The betting odds from DraftKings had the Padres at -115 on the money line, with a spread of 1.5 and a total set at 9.0. The over odds were listed at 101.0, while the under odds were at -122. The market reflected a competitive matchup, with both teams having shown strong performances leading into the game.

Overall, this game was a testament to the competitive nature of both teams, with the Cubs managing to edge out the Padres in a closely fought contest. The series victory will likely serve as a confidence booster for the Cubs as they continue their season, while the Padres will look to regroup and address their injury concerns moving forward.

Odds

BookSpreadTotalMoneyline
DraftKingsSD -115 9 o +101 / u -122 Chicago Cubs -105 · San Diego Padres -115

What these prices pay on $100 · What these numbers mean

Injury report

  • Jason Adam60-Day-ILShoulderSan Diego Padres
  • Miguel Andujar10-Day-ILWristSan Diego Padres
  • Gavin Sheets10-Day-ILFootSan Diego Padres
  • Jeremiah Estrada15-Day-ILShoulderSan Diego Padres
  • Lucas Giolito60-Day-ILElbowSan Diego Padres
  • Edward Cabrera15-Day-ILFingerChicago Cubs
  • Shelby Miller60-Day-ILElbowChicago Cubs
  • Jacob WebbDay-To-DayArmChicago Cubs
  • Pedro RamirezDay-To-DayBackChicago Cubs
  • Gavin Hollowell15-Day-ILShoulderChicago Cubs

Recent form

San Diego Padres

Last 10: 7-3Streak W14.6 scored · 4.9 allowed per game4-0 at home

  • W9-7vs Chicago CubsApr 28
  • L7-12at Arizona DiamondbacksApr 26
  • W6-4at Arizona DiamondbacksApr 25
  • L3-8at Colorado RockiesApr 23
  • W1-0at Colorado RockiesApr 22
  • W4-1at Los Angeles AngelsApr 19
  • L0-8at Los Angeles AngelsApr 18
  • W5-2vs Seattle MarinersApr 17
  • W7-6vs Seattle MarinersApr 16
  • W4-1vs Seattle MarinersApr 15

Chicago Cubs

Last 10: 8-2Streak L25.8 scored · 4 allowed per game1-2 away

  • L7-9at San Diego PadresApr 28
  • L0-6at Los Angeles DodgersApr 26
  • W6-4at Los Angeles DodgersApr 25
  • W8-7vs Philadelphia PhilliesApr 23
  • W7-2vs Philadelphia PhilliesApr 22
  • W7-4vs Philadelphia PhilliesApr 21
  • W5-1vs Philadelphia PhilliesApr 20
  • W2-1vs New York MetsApr 19
  • W4-2vs New York MetsApr 18
  • W12-4vs New York MetsApr 17

Standings

TeamGames behindLostStreakWin %Won
Milwaukee-53W2.62187
Chicago962L2.55778
St. Louis1770W2.50070
Pittsburgh1972L1.48668
Cincinnati2073W2.47967
Los Angeles-57L2.59082
Arizona967W1.52574
San Diego9.567L2.52173
San Francisco24.582W1.41458
Colorado28.586W2.38654

How the scoring went

  1. 2nd Inning1-0Amaya singled to center, Conforto scored.
  2. 4th Inning3-0Crow-Armstrong homered to right (357 feet), Shaw scored.
  3. 5th Inning3-1Andujar homered to left (387 feet).
  4. 5th Inning3-3Castellanos homered to left center (405 feet), Cronenworth scored.
  5. 6th Inning4-3Crow-Armstrong grounded out to first, Conforto scored, Shaw to third.
  6. 8th Inning5-3Shaw homered to left (351 feet).
  7. 8th Inning5-4Tatis Jr. hit sacrifice fly to center, Castellanos scored, Johnson to third.

Win probability

Above the line favours San Diego Padres, below favours Chicago Cubs.

Venue

  • Petco ParkSan Diego, California
  • Attendance36513
  • OfficialsMark Ripperger, Shane Livensparger, Dan Merzel, Dan Bellino

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.