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MLB · Final

Cubs Dominate Cardinals in 10-2 Victory

Tuesday, July 28, 2026, 7:45 PM ET · Busch Stadium

Chicago Cubs 10, St. Louis Cardinals 2, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Chicago Cubs vs St. Louis Cardinals?

Chicago Cubs beat St. Louis Cardinals 10-2 at Busch Stadium on July 28, 2026.

Who was favored in Chicago Cubs vs St. Louis Cardinals?

St. Louis Cardinals were the favorite at DraftKings, moneyline -112 (about 53% implied). The underdog won.

In a decisive matchup at Busch Stadium, the Chicago Cubs defeated the St. Louis Cardinals 10-2, marking a significant win in their series, which they took 3-1. This game showcased the Cubs' offensive prowess, as they scored in multiple innings, with a particularly strong second inning where they put up seven runs.

The Cubs entered the game with a record of 61-46, having won six of their last ten games, and were on a one-game winning streak. They averaged 6.6 runs scored and 3.8 runs allowed during this stretch. Their recent form included a victory over the Cardinals the previous day, where they won 7-3. In contrast, the Cardinals struggled with a record of 53-54, having lost eight of their last ten games, including seven in a row. Their average runs scored during this period was 3.4, while they allowed 5.1 runs per game. This stark difference in form was evident in the game, as the Cardinals could only muster two runs against a potent Cubs lineup.

At home, the Cardinals had a record of 1-5 in their last six games, while the Cubs were 4-1 in their last five away games. The head-to-head record between the two teams stood at 9-9, indicating a competitive rivalry, but the Cubs had dominated the recent meetings, winning three of the last four encounters. This game added to that trend, as the Cubs continued their successful run against the Cardinals.

In terms of injuries, the Cardinals faced challenges with several players on the injured list. Everson Pereira and Masyn Winn were both on the 10-Day Injured List, while Ramon Urias was listed as day-to-day with an arm issue. Andre Pallante was on the 15-Day Injured List due to an elbow problem, and JJ Wetherholt was also on the 10-Day IL with a wrist injury. The Cubs, too, had injury concerns, with Edward Cabrera on the 15-Day IL due to a finger issue, Shelby Miller on the 60-Day IL with an elbow injury, and Gavin Hollowell on the 15-Day IL with a shoulder problem. Jacob Webb and Pedro Ramirez were both listed as day-to-day, adding to the uncertainty surrounding their lineup.

The betting odds provided by DraftKings reflected the competitive nature of the matchup, with the Cardinals at -112 on the money line and the Cubs slightly behind at -108. The spread was set at 1.5, with a total of 8.5 runs for the game, indicating expectations of a relatively high-scoring affair. The over was priced at -119, while the under was at -101, suggesting that bookmakers anticipated a game that could see a significant number of runs.

The conditions at Busch Stadium were conducive to scoring, which played a role in the Cubs' offensive explosion. They capitalized on their opportunities, particularly in the second inning, where they scored seven runs, including a double from Seiya Suzuki that set the tone for the inning. Other key plays included a single from Christopher Morel and a sacrifice fly from Jordan Church that contributed to the Cubs' lead.

The Cardinals managed to score two runs, with a ground rule double from Masyn Winn in the ninth inning providing a small consolation. However, the game was largely dominated by the Cubs, who showcased their ability to capitalize on mistakes and create scoring opportunities.

Overall, this game highlighted the contrasting fortunes of the two teams, with the Cubs solidifying their position in the playoff race while the Cardinals continued to struggle. The performance of both teams in this matchup will likely have implications for their respective seasons moving forward.

Odds

BookSpreadTotalMoneyline
DraftKingsSTL -112 8.5 o -119 / u -101 Chicago Cubs -108 · St. Louis Cardinals -112

What these prices pay on $100 · What these numbers mean

Injury report

  • Everson Pereira10-Day-ILHandSt. Louis Cardinals
  • Ramon UriasDay-To-DayArmSt. Louis Cardinals
  • Masyn Winn10-Day-ILThumbSt. Louis Cardinals
  • Andre Pallante15-Day-ILElbowSt. Louis Cardinals
  • JJ Wetherholt10-Day-ILWristSt. Louis Cardinals
  • Edward Cabrera15-Day-ILFingerChicago Cubs
  • Shelby Miller60-Day-ILElbowChicago Cubs
  • Jacob WebbDay-To-DayArmChicago Cubs
  • Pedro RamirezDay-To-DayBackChicago Cubs
  • Gavin Hollowell15-Day-ILShoulderChicago Cubs

Recent form

St. Louis Cardinals

Last 10: 2-8Streak L73.4 scored · 5.1 allowed per game1-5 at home

  • L3-7vs Chicago CubsJul 27
  • L3-5vs Cincinnati RedsJul 26
  • L2-4vs Cincinnati RedsJul 25
  • L6-10vs Arizona DiamondbacksJul 23
  • L1-5at Los Angeles AngelsJul 22
  • L2-3at Los Angeles AngelsJul 21
  • L7-8at Arizona DiamondbacksJul 19
  • W5-4at Arizona DiamondbacksJul 18
  • L3-4vs Atlanta BravesJul 12
  • W2-1vs Atlanta BravesJul 11

Chicago Cubs

Last 10: 6-4Streak W16.6 scored · 3.8 allowed per game4-1 away

  • W7-3at St. Louis CardinalsJul 27
  • L7-8at Pittsburgh PiratesJul 26
  • W11-0at Pittsburgh PiratesJul 25
  • W3-2at Pittsburgh PiratesJul 24
  • L1-5vs Detroit TigersJul 23
  • W11-2vs Detroit TigersJul 22
  • L6-8vs Detroit TigersJul 21
  • W10-1vs Minnesota TwinsJul 19
  • L2-5vs Minnesota TwinsJul 18
  • W8-4at Cincinnati RedsJul 12

Standings

TeamGames behindLostStreakWin %Won
Milwaukee-53W2.62187
Chicago962L2.55778
St. Louis1770W2.50070
Pittsburgh1972L1.48668
Cincinnati2073W2.47967

How the scoring went

  1. 1st Inning2-0Happ doubled to right, Bregman scored and Suzuki scored.
  2. 2nd Inning3-0Crow-Armstrong hit sacrifice fly to center, Conforto scored, Kelly to third.
  3. 2nd Inning4-0Suzuki doubled to left, Kelly scored.
  4. 2nd Inning5-0Busch singled to right, Suzuki scored.
  5. 2nd Inning7-0Hoerner singled to right, Bregman scored and Busch scored, Happ to third.
  6. 4th Inning7-1Church hit sacrifice fly to right, Burleson scored.
  7. 5th Inning8-1Ramirez reached on infield single to third, Hoerner scored.
  8. 8th Inning9-1Suzuki singled to center, Ramirez scored.
  9. 9th Inning10-1Kelly singled to center, Happ scored, Dean to third.
  10. 9th Inning10-2Winn hit a ground rule double, Nootbaar scored.

Win probability

Above the line favours St. Louis Cardinals, below favours Chicago Cubs.

Venue

  • Busch StadiumSt. Louis, Missouri
  • Attendance29097
  • OfficialsAdam Hamari, Todd Tichenor, Tyler Jones, Clint Vondrak

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.