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MLB · Final

White Sox Defeat Astros 6-3 in MLB Showdown

Tuesday, September 29, 2026, 5:00 PM ET · Daikin Park

Quick answers

Who won Chicago White Sox vs Houston Astros?

Chicago White Sox beat Houston Astros 6-3 at Daikin Park on September 29, 2026.

Who was favored in Chicago White Sox vs Houston Astros?

Houston Astros were the favorite at DraftKings, moneyline -123 (about 55% implied). The underdog won.

In a decisive matchup at Daikin Park, the Chicago White Sox emerged victorious against the Houston Astros with a final score of 6-3. This victory gives the White Sox a 2-0 lead in their series against the Astros, having previously won their first meeting earlier this season. The White Sox's recent form has shown some inconsistency, but they managed to capitalize on their opportunities in this game. Over their last ten games, the White Sox recorded a 3-7 record, averaging 3.9 runs scored and allowing 4.7 runs per game. Their last five games saw them slightly improve to a 2-3 record with an average of 5.4 runs scored and 5.6 runs allowed. In contrast, the Astros finished the season with an 81-81 record and have struggled recently, going 4-6 in their last ten games, with an average of 3.3 runs scored and 4.5 runs allowed. They have been particularly challenged at home, where they have a 3-2 record in their last five games.

The game began with the White Sox taking an early lead in the first inning when Murakami hit a sacrifice fly to right, allowing Antonacci to score. The second inning saw the White Sox extend their lead to 3-0, as Antonacci singled to left, scoring both B. Montgomery and Meidroth. C. Montgomery added to the score in the fourth inning with a home run that traveled 432 feet, making it 4-0. The Astros managed to get on the board in the fifth inning, with Velázquez hitting a home run of his own, but the White Sox responded immediately, with Meidroth reaching on an infield single that allowed Murakami to score, pushing the lead to 5-2.

In the seventh inning, the White Sox increased their lead to 6-2, as Murakami scored on a wild pitch by Sousa. The Astros attempted a late rally in the eighth inning, with Peña scoring on a throwing error by third baseman Vargas, but it was not enough to overcome the deficit. The White Sox's pitching and timely hitting proved to be the difference in this game.

In terms of injuries, the Astros were missing several key players, including Mike Burrows, who is on the 60-day injured list with an elbow issue, and Steven Okert, who is on the 15-day injured list due to a hamstring injury. Other players affected included Ethan Pecko, Daulton Varsho, and Brice Matthews, all of whom were sidelined with various injuries. The White Sox also faced challenges, with Jake Rogers absent for personal reasons, and several players, including Prelander Berroa and Joey Bart, on the injured list.

The betting odds from DraftKings indicated that the Astros were favored at -123, with a spread of -1.5 and a total set at 8.5. The White Sox's money line was priced at 102. The conditions for the game were typical for late September, with players needing to adapt to the cooler weather as the season winds down.

Overall, viewers should have watched for the White Sox's ability to capitalize on scoring opportunities and how their pitching staff managed to contain the Astros' lineup. The game showcased the White Sox's resilience and ability to perform under pressure, while the Astros will need to regroup and reassess their strategy moving forward.

What we said beforehand

The Houston Astros will face the Chicago White Sox at Daikin Park on September 29, 2026, in a matchup that is significant as the Astros look to improve their standing in the league. The Astros have won the series against the White Sox 5-2, which adds an intriguing layer to this contest. Both teams have had their ups and downs recently, making this game worth watching.

In their last five games, the Astros have a record of 3-2, with their most recent results showing a mix of performances. They lost to the Seattle Mariners 6-5 in a tightly contested game that went into extra innings, followed by a win against the Athletics, where they triumphed 7-5. However, they also faced setbacks against the Athletics, losing 6-5 before bouncing back with dominant victories of 13-2 and 9-0 in subsequent games. Overall, the Astros have averaged 5.2 runs scored per game in their last five outings.

Conversely, the White Sox have a record of 3-2 in their last five games as well. They began with a narrow loss to the Kansas City Royals, falling 5-4, but quickly rebounded with a decisive 9-1 victory over the same team. They then faced the Colorado Rockies, winning one game 6-1 but losing two others with scores of 9-6 and 4-2. The White Sox have averaged 4.4 runs scored per game in their recent performances.

When considering home versus away performance, the Astros have a home record of 81-81, while the White Sox have an away record of 84-78. This suggests that the White Sox have been slightly more successful on the road compared to the Astros at home. The Astros have struggled recently at home, going 4-6 in their last ten games, with an average of 3.3 runs scored and 4.5 runs allowed. In contrast, the White Sox have a record of 3-7 in their last ten away games, averaging 3.9 runs scored and allowing 4.7 runs.

In terms of injuries, the Astros will be missing several key players, including Mike Burrows (elbow, 60-Day IL), Steven Okert (hamstring, 15-Day IL), Daulton Varsho (wrist, 10-Day IL), Brice Matthews (knee, 10-Day IL), and Ethan Pecko (hip, day-to-day). The White Sox will also be without Jake Rogers (personal, paternity), Prelander Berroa (elbow, 60-Day IL), Joey Bart (hand, 10-Day IL), Tanner Murray (shoulder, 60-Day IL), and Luis Castillo (shoulder, 15-Day IL).

The betting market has priced the Astros at -123 according to DraftKings, with a spread of -1.5 and a total set at 8.0. The odds for the over are -118, while the under sits at -102. This indicates a competitive matchup where the Astros are slightly favored to win.

Weather conditions for the game are expected to be warm, with a temperature of 79°F and a 90% chance of precipitation. Wind gusts could reach up to 23 mph, potentially impacting gameplay.

Key players to watch include Yordan Alvarez for the Astros, who leads the team with a batting average of .316, 42 home runs, and 106 runs batted in. For the White Sox, Sam Antonacci boasts a batting average of .277, while Munetaka Murakami has hit 35 home runs, and Miguel Vargas has driven in 93 runs. Their performances could be pivotal in determining the outcome of this matchup.

Odds

BookSpreadTotalMoneyline
DraftKingsHOU -123 8.5 o -106 / u -114 Chicago White Sox +102 · Houston Astros -123

What these prices pay on $100 · What these numbers mean

Injury report

  • Mike Burrows60-Day-ILElbowHouston Astros
  • Steven Okert15-Day-ILHamstringHouston Astros
  • Ethan PeckoDay-To-DayHipHouston Astros
  • Daulton Varsho10-Day-ILWristHouston Astros
  • Brice Matthews10-Day-ILKneeHouston Astros
  • Jake RogerspaternityPersonalChicago White Sox
  • Prelander Berroa60-Day-ILElbowChicago White Sox
  • Joey Bart10-Day-ILHandChicago White Sox
  • Tanner Murray60-Day-ILShoulderChicago White Sox
  • Luis Castillo15-Day-ILShoulderChicago White Sox

Recent form

Houston Astros

Last 10: 4-6Streak W13.3 scored · 4.5 allowed per game3-2 at home

  • W6-1at Los Angeles AngelsSep 28
  • L3-4at Los Angeles AngelsSep 27
  • L0-6at AthleticsSep 25
  • L1-5at AthleticsSep 24
  • L3-7vs Seattle MarinersSep 21
  • L0-4vs Seattle MarinersSep 20
  • W5-2vs Texas RangersSep 18
  • W6-5vs Texas RangersSep 17
  • W6-3vs Texas RangersSep 16
  • L3-8at Atlanta BravesSep 14

Chicago White Sox

Last 10: 3-7Streak W13.9 scored · 4.7 allowed per game2-4 away

  • W8-0at Washington NationalsSep 28
  • L5-6at Washington NationalsSep 27
  • W10-9at Washington NationalsSep 26
  • L3-5at New York YankeesSep 25
  • L1-8at New York YankeesSep 24
  • L2-3at New York YankeesSep 23
  • L2-3vs San Diego PadresSep 21
  • L3-7vs San Diego PadresSep 20
  • W4-3vs San Diego PadresSep 19
  • L1-3vs Baltimore OriolesSep 17

Standings

TeamGames behindLostStreakWin %Won
Cleveland-77L1.52585
Chicago178W1.51984
Minnesota885W1.47577
Detroit986L1.46976
Kansas City1693W1.42669
Houston-81W2.50081
Texas182L1.49480
Seattle586W2.46976
Athletics1798L2.39564
Los Angeles19100L2.38362

How the scoring went

  1. 1st Inning1-0Murakami hit sacrifice fly to right, Antonacci scored.
  2. 2nd Inning3-0Antonacci singled to left, B. Montgomery scored and Meidroth scored, C. Montgomery to second.
  3. 4th Inning4-0C. Montgomery homered to center (432 feet).
  4. 5th Inning5-0Meidroth reached on infield single to shortstop, Murakami scored, B. Montgomery to second, Peters to third.
  5. 5th Inning5-2Velázquez homered to left (388 feet), Spence scored.
  6. 7th Inning6-2Murakami scored on Sousa wild pitch, Grichuk to third on wild pitch by Sousa.
  7. 7th Inning6-2Murakami scored on Sousa wild pitch, Grichuk to third.
  8. 8th Inning6-3Peña scored, Altuve safe at first on throwing error by third baseman Vargas, Alvarez to second. Chicago White Sox challenged: call on the field was upheld.

Win probability

Above the line favours Houston Astros, below favours Chicago White Sox.

Venue

  • Daikin ParkHouston, Texas
  • Attendance34011
  • OfficialsAlex MacKay, Alex Tosi, Ryan Additon, Alan Porter, Edwin Moscoso, Paul Clemons

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.