White Sox Defeat Giants 9-4 in Series Finale
Friday, May 22, 2026, 10:15 PM ET · Oracle Park
Chicago White Sox 9, San Francisco Giants 4, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.
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Quick answers
Who won Chicago White Sox vs San Francisco Giants?
Chicago White Sox beat San Francisco Giants 9-4 at Oracle Park on May 22, 2026.
Who was favored in Chicago White Sox vs San Francisco Giants?
Chicago White Sox were the favorite at DraftKings, moneyline -120 (about 55% implied). The favorite won.
The Chicago White Sox secured a decisive victory against the San Francisco Giants, winning 9-4 at Oracle Park. This result allowed the White Sox to take the series 2-1, showcasing their strong form as they continue to compete in the MLB. The White Sox's recent performance has been impressive, boasting a record of 8-2 over their last ten games, with an average of 5.1 runs scored and 4.2 runs allowed per game. Their latest win against the Seattle Mariners on May 20, where they triumphed 2-1, further solidified their momentum.
In contrast, the San Francisco Giants have struggled, recording only 4 wins in their last 10 games, with an average of 3.8 runs scored and 5.5 runs allowed. They have now lost their last two games, including a defeat to the Arizona Diamondbacks prior to facing the White Sox. The Giants' home record stands at 20-31, while the White Sox have performed better on the road, holding a 26-24 record overall.
The game was characterized by a dominant fourth inning for the White Sox, where they scored 5 runs, effectively sealing their victory. Key plays included Quero's fielder's choice that allowed Meidroth to score, followed by Hill's single that brought in Benintendi. Murakami then doubled to left field, scoring Antonacci, Quero, and Hill, pushing the score to 8-0. Vargas capped off the inning with an infield single that resulted in a throwing error, allowing Murakami to score and extending the lead to 9-0.
The Giants managed to respond in the fifth inning, scoring 4 runs, but it was not enough to close the gap. Adames grounded into a fielder's choice that allowed J. Rodríguez to score, followed by Arraez's single that brought Gilbert home. Schmitt's groundout added another run, and J. Rodríguez's groundout in the sixth inning brought the score to 9-4.
In terms of injuries, the Giants were missing several key players, including Victor Bericoto, Marcelo Mayer, JT Brubaker, Keaton Winn, and Matt Gage, all of whom are currently on the injured list. The White Sox also faced injury challenges with Chris Murphy, Kyle Teel, Tanner Murray, Drew Thorpe, and Huascar Brazoban sidelined.
The betting odds from DraftKings favored the White Sox at -120, with a spread of 1.5 and a total set at 7.5. The conditions at Oracle Park were conducive to baseball, as fans witnessed an engaging matchup between two teams with contrasting recent performances.
Overall, the White Sox's offensive prowess and the Giants' struggles were on full display, making this game a notable fixture in the MLB schedule.
Odds
| Book | Spread | Total | Moneyline |
|---|---|---|---|
| DraftKings | CHW -120 | 7.5 o +100 / u -120 | Chicago White Sox -120 · San Francisco Giants +100 |
Injury report
- Victor Bericoto10-Day-ILKneeSan Francisco Giants
- Marcelo Mayer10-Day-ILForearmSan Francisco Giants
- JT Brubaker15-Day-ILRibsSan Francisco Giants
- Keaton Winn15-Day-ILElbowSan Francisco Giants
- Matt Gage60-Day-ILElbowSan Francisco Giants
- Chris Murphy15-Day-ILForearmChicago White Sox
- Kyle Teel10-Day-ILAnkleChicago White Sox
- Tanner Murray60-Day-ILShoulderChicago White Sox
- Drew Thorpe60-Day-ILElbowChicago White Sox
- Huascar Brazoban15-Day-ILLatChicago White Sox
Recent form
San Francisco Giants
Last 10: 4-6Streak L23.8 scored · 5.5 allowed per game1-1 at home
- L3-5at Arizona DiamondbacksMay 20
- L2-12at Arizona DiamondbacksMay 19
- W6-4at AthleticsMay 17
- L2-5at AthleticsMay 16
- L2-5at Los Angeles DodgersMay 15
- L0-4at Los Angeles DodgersMay 14
- W6-2at Los Angeles DodgersMay 13
- W9-3at Los Angeles DodgersMay 12
- L3-13vs Pittsburgh PiratesMay 10
- W5-2vs Pittsburgh PiratesMay 9
Chicago White Sox
Last 10: 8-2Streak W15.1 scored · 4.2 allowed per game1-1 away
- W2-1at Seattle MarinersMay 20
- L1-6at Seattle MarinersMay 19
- W9-8vs Chicago CubsMay 17
- W8-3vs Chicago CubsMay 16
- L5-10vs Chicago CubsMay 15
- W6-2vs Kansas City RoyalsMay 14
- W6-5vs Kansas City RoyalsMay 13
- W6-5vs Kansas City RoyalsMay 12
- W2-1vs Seattle MarinersMay 10
- W6-1vs Seattle MarinersMay 9
Standings
| Team | Games behind | Lost | Streak | Win % | Won |
|---|---|---|---|---|---|
| Chicago | - | 66 | L1 | .525 | 73 |
| Cleveland | 3 | 69 | L1 | .504 | 70 |
| Minnesota | 6.5 | 73 | L1 | .479 | 67 |
| Detroit | 9 | 75 | W1 | .460 | 64 |
| Kansas City | 11.5 | 78 | L3 | .443 | 62 |
| Los Angeles | - | 57 | L2 | .590 | 82 |
| Arizona | 9 | 67 | W1 | .525 | 74 |
| San Diego | 9.5 | 67 | L2 | .521 | 73 |
| San Francisco | 24.5 | 82 | W1 | .414 | 58 |
| Colorado | 28.5 | 86 | W2 | .386 | 54 |
How the scoring went
- 4th Inning1-0Meidroth walked, Antonacci scored, Montgomery to second, Murakami to third.
- 4th Inning3-0Benintendi doubled to center, Murakami scored and Montgomery scored, Meidroth to third.
- 4th Inning4-0Quero grounded into fielder's choice to second, Meidroth scored, Benintendi third.
- 4th Inning5-0Hill singled to right, Benintendi scored, Quero to second.
- 4th Inning8-0Murakami doubled to left, Antonacci scored, Quero scored and Hill scored.
- 4th Inning9-0Vargas reached on infield single to shortstop, Murakami scored on throwing error by shortstop Adames.
- 5th Inning9-1Adames grounded into fielder's choice to shortstop, J. Rodríguez scored, Bader out at second, Gilbert to third.
- 5th Inning9-2Arraez singled to left, Gilbert scored, Adames to second.
- 5th Inning9-3Schmitt grounded out to shortstop, Adames scored, Arraez to third.
- 6th Inning9-4J. Rodríguez grounded out to third, Chapman scored.
Win probability
Above the line favours San Francisco Giants, below favours Chicago White Sox.
Venue
- Oracle ParkSan Francisco, California
- Attendance37524
- OfficialsNestor Ceja, Louie Krupa, Chris Guccione, David Rackley