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MLB · Final

Cleveland Guardians Dominate Chicago White Sox 12-3

Thursday, March 5, 2026, 8:05 PM ET · Camelback Ranch - Glendale

Cleveland Guardians 12, Chicago White Sox 3, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Cleveland Guardians vs Chicago White Sox?

Cleveland Guardians beat Chicago White Sox 12-3 at Camelback Ranch - Glendale on March 5, 2026.

In a decisive matchup at Camelback Ranch - Glendale, the Cleveland Guardians overwhelmed the Chicago White Sox with a final score of 12-3. This game marked the third encounter of the series, leaving it tied at 1-1 after the previous two contests. The Guardians showcased their offensive strength, particularly in the seventh inning, where they scored a staggering eight runs, effectively sealing the game.

The Guardians entered this game on a two-game winning streak, having won seven of their last ten games, with an average of 4.2 runs scored and only 3.3 runs allowed per game. Their recent form reflects a strong performance, particularly against teams like the Texas Rangers, whom they defeated in their last two outings. In contrast, the White Sox have struggled recently, winning only three of their last ten games, with an average of 3.9 runs scored and 4.7 runs allowed per game. This stark contrast in form was evident throughout the game.

At home, the White Sox have recorded a 1-3 record in their last four games, while the Guardians have fared better on the road with a 3-1 record in their last four away games. Historically, the Guardians have dominated this matchup, with a record of 10 wins, 2 losses, and 1 tie against the White Sox in their last 13 meetings.

In terms of injuries, the White Sox faced significant challenges with multiple players on the injured list, including Chris Murphy (forearm), Kyle Teel (ankle), Tanner Murray (shoulder), Drew Thorpe (elbow), and Huascar Brazoban (lat). The Guardians also had their share of injuries, with Slade Cecconi (arm), Rhys Hoskins (back), and Shawn Armstrong (calf) unable to participate.

The betting market reflected the Guardians' stronger recent performance, with odds favoring them significantly, suggesting a high probability of a win for Cleveland. The conditions at Camelback Ranch were conducive to a high-scoring game, which was evident in the Guardians' offensive explosion.

Key moments in the game included a series of impressive scoring plays in the seventh inning, where Genao doubled to center, allowing Rodríguez to score, followed by a home run from Tolentino that brought in two more runs. The Guardians continued their offensive barrage with additional runs from Antunez and Kieboom, leading to a commanding 11-0 lead before the White Sox managed to score their first run in the same inning.

Despite the White Sox's efforts in the ninth inning, where they scored two runs, it was too little, too late as the Guardians had already established a significant lead. The final score of 12-3 underscored the Guardians' dominance in this matchup, showcasing their ability to capitalize on scoring opportunities while the White Sox struggled to keep pace.

Injury report

  • Chris Murphy15-Day-ILForearmChicago White Sox
  • Kyle Teel10-Day-ILAnkleChicago White Sox
  • Tanner Murray60-Day-ILShoulderChicago White Sox
  • Drew Thorpe60-Day-ILElbowChicago White Sox
  • Huascar Brazoban15-Day-ILLatChicago White Sox
  • Slade Cecconi15-Day-ILArmCleveland Guardians
  • Rhys Hoskins10-Day-ILBackCleveland Guardians
  • Shawn Armstrong60-Day-ILCalfCleveland Guardians

Recent form

Chicago White Sox

Last 10: 3-7Streak W13.9 scored · 4.7 allowed per game1-3 at home

  • W8-0at Washington NationalsSep 28
  • L5-6at Washington NationalsSep 27
  • W10-9at Washington NationalsSep 26
  • L3-5at New York YankeesSep 25
  • L1-8at New York YankeesSep 24
  • L2-3at New York YankeesSep 23
  • L2-3vs San Diego PadresSep 21
  • L3-7vs San Diego PadresSep 20
  • W4-3vs San Diego PadresSep 19
  • L1-3vs Baltimore OriolesSep 17

Cleveland Guardians

Last 10: 7-3Streak W24.2 scored · 3.3 allowed per game3-1 away

  • W9-8vs Texas RangersSep 28
  • W3-2vs Texas RangersSep 27
  • L3-7vs Texas RangersSep 26
  • L2-4vs Detroit TigersSep 25
  • W5-1vs Detroit TigersSep 24
  • W5-2vs Detroit TigersSep 23
  • L2-6at Minnesota TwinsSep 21
  • W6-2at Minnesota TwinsSep 20
  • W3-1at Detroit TigersSep 18
  • W4-0at Detroit TigersSep 17

Standings

TeamGames behindLostStreakWin %Won
Chicago-66L1.52573
Cleveland369L1.50470
Minnesota6.573L1.47967
Detroit975W1.46064
Kansas City11.578L3.44362

How the scoring went

  1. 1st Inning1-0Rocchio doubled to right, A. Martinez scored.
  2. 1st Inning2-0Valera doubled to center, Rocchio scored.
  3. 1st Inning4-0Kayfus homered to center (429 feet), Valera scored.
  4. 7th Inning5-0Genao doubled to center, John. Rodríguez scored.
  5. 7th Inning8-0Tolentino homered to right center (377 feet), Genao scored and Chourio scored.
  6. 7th Inning9-0Antunez singled to center, Huff scored.
  7. 7th Inning11-0Kieboom homered to left (404 feet), Antunez scored.
  8. 7th Inning11-1Dru Baker tripled to right, Dru Baker scored on throwing error by shortstop Tolentino.
  9. 9th Inning12-1Mooney singled to center, Huff scored, Mooney out stretching at second.
  10. 9th Inning12-2Weber singled to right, Da. Baker scored, Galanie to third.
  11. 9th Inning12-3Connor singled to left, Galanie scored, Weber to second.

Win probability

Above the line favours Chicago White Sox, below favours Cleveland Guardians.

Venue

  • Camelback Ranch - GlendalePhoenix, Arizona
  • Attendance3933
  • OfficialsDillon Wilson, Mark Ripperger, Ryan Blakney, Sean Sparling

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.