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MLB · Final

Orioles Secure Series Win Over Astros with 5-3 Victory

Tuesday, April 28, 2026, 6:35 PM ET · Oriole Park at Camden Yards

Baltimore Orioles 5, Houston Astros 3, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Houston Astros vs Baltimore Orioles?

Baltimore Orioles beat Houston Astros 5-3 at Oriole Park at Camden Yards on April 28, 2026.

Who was favored in Houston Astros vs Baltimore Orioles?

Baltimore Orioles were the favorite at DraftKings, moneyline -131 (about 57% implied). The favorite won.

The Baltimore Orioles triumphed over the Houston Astros with a final score of 5-3, clinching the series 2-1 at Oriole Park at Camden Yards. This victory is particularly noteworthy as it showcases the Orioles' ability to bounce back after recent struggles, having lost their last two games prior to this matchup.

In their last ten games, the Orioles recorded a record of 4-6, with an average of 4.8 runs scored and 6.2 runs allowed per game. Their recent performance at home has been less than stellar, with a home record of 1-2 in their last three games. In contrast, the Astros have shown a more balanced form, finishing their last ten games with a 5-5 record, averaging 4.8 runs scored and 5.2 runs allowed. The Astros' away record stands at 2-1 in their last three games, indicating a slight edge in their recent performances compared to the Orioles.

The scoring in this game began in the first inning when Adley Rutschman singled to left field, allowing Gunnar Henderson to score, followed by a double from Samuel Basallo that brought Rutschman home, giving the Orioles an early 2-0 lead. The Astros responded in the fifth inning with a homer from Brice Matthews, narrowing the gap to 2-1. However, the Orioles quickly regained control with a two-run homer from Pete Alonso, extending their lead to 4-1.

Rutschman further solidified the Orioles' advantage in the seventh inning with another single that scored Henderson, making it 5-1. The Astros attempted a comeback in the eighth inning, as Harris tripled to right field, scoring Walker, and Matthews added a single that brought Harris home, reducing the deficit to 5-3. Despite the late surge, the Orioles maintained their lead to secure the victory.

In terms of injuries, the Orioles are currently without several key players, including Tyler O'Neill (10-Day IL, shoulder), Felix Bautista (60-Day IL, shoulder), Christian Franklin (10-Day IL, hand), Ryan Helsley (60-Day IL, elbow), and Ryan Mountcastle (60-Day IL, oblique). The Astros also face challenges with Brice Matthews (60-Day IL, knee), Mike Burrows (15-Day IL, elbow), Carlos Correa (60-Day IL, ankle), and Brandon Walter (60-Day IL, elbow) on the injured list.

The betting odds from DraftKings reflected the competitive nature of the matchup, with the Orioles favored at -131, while the Astros were priced at +109. The spread was set at -1.5 for the Orioles, with a total of 9.0 runs for the game, indicating expectations of a moderately high-scoring affair.

The conditions for the game were typical for a late-April evening in Baltimore, with fans witnessing an engaging contest that highlighted both teams' strengths and weaknesses. Viewers should have noted the Orioles' ability to capitalize on scoring opportunities, particularly through Rutschman's contributions, and the Astros' resilience in fighting back late in the game.

Overall, this game served as a significant moment for the Orioles as they look to build momentum in the season, while the Astros will need to regroup and address their recent inconsistencies.

Odds

BookSpreadTotalMoneyline
DraftKingsBAL -131 9 o -115 / u -105 Houston Astros +109 · Baltimore Orioles -131

What these prices pay on $100 · What these numbers mean

Injury report

  • Tyler O'Neill10-Day-ILShoulderBaltimore Orioles
  • Felix Bautista60-Day-ILShoulderBaltimore Orioles
  • Christian Franklin10-Day-ILHandBaltimore Orioles
  • Ryan Helsley60-Day-ILElbowBaltimore Orioles
  • Ryan Mountcastle60-Day-ILObliqueBaltimore Orioles
  • Brice Matthews60-Day-ILKneeHouston Astros
  • Mike Burrows15-Day-ILElbowHouston Astros
  • Carlos Correa60-Day-ILAnkleHouston Astros
  • Brandon Walter60-Day-ILElbowHouston Astros

Recent form

Baltimore Orioles

Last 10: 4-6Streak L24.8 scored · 6.2 allowed per game1-2 at home

  • L3-5vs Boston Red SoxApr 26
  • L1-17vs Boston Red SoxApr 25
  • W10-3vs Boston Red SoxApr 24
  • W8-6at Kansas City RoyalsApr 22
  • L5-6at Kansas City RoyalsApr 21
  • W7-5at Kansas City RoyalsApr 20
  • L4-8at Cleveland GuardiansApr 19
  • L2-4at Cleveland GuardiansApr 18
  • W6-4at Cleveland GuardiansApr 17
  • L2-4at Cleveland GuardiansApr 16

Houston Astros

Last 10: 5-5Streak W14.8 scored · 5.2 allowed per game2-1 away

  • W7-4vs New York YankeesApr 26
  • L4-12vs New York YankeesApr 25
  • W2-0at Cleveland GuardiansApr 22
  • L5-8at Cleveland GuardiansApr 21
  • W9-2at Cleveland GuardiansApr 20
  • L5-7vs St. Louis CardinalsApr 19
  • L4-9vs St. Louis CardinalsApr 18
  • L2-3vs Colorado RockiesApr 17
  • W3-1vs Colorado RockiesApr 16
  • W7-6vs Colorado RockiesApr 15

Standings

TeamGames behindLostStreakWin %Won
Houston-69W1.50771
Texas271L1.49369
Seattle574W2.47166
Athletics1786W1.38654
Los Angeles1887L2.37953
Tampa Bay-56L1.59783
New York3.560W2.57180
Boston8.565L2.53675
Toronto14.571W1.49369
Baltimore14.571L2.49369

How the scoring went

  1. 1st Inning0-1Rutschman singled to left, Henderson scored.
  2. 1st Inning0-2Basallo doubled to right, Rutschman scored.
  3. 5th Inning1-2Matthews homered to right center (387 feet).
  4. 5th Inning1-4Alonso homered to right center (380 feet), Ward scored.
  5. 7th Inning1-5Rutschman singled to center, Henderson scored.
  6. 8th Inning2-5Harris tripled to right, Walker scored.
  7. 8th Inning3-5Matthews singled to right, Harris scored.

Win probability

Above the line favours Baltimore Orioles, below favours Houston Astros.

Venue

  • Oriole Park at Camden YardsBaltimore, Maryland
  • Attendance13233
  • OfficialsJordan Baker, Rob Drake, Stu Scheurwater, Junior Valentine

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.