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MLB · Final

Astros Dominate Angels in Final Game of Series

Saturday, September 27, 2025, 9:38 PM ET · Angel Stadium

Houston Astros 6, Los Angeles Angels 1, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Houston Astros vs Los Angeles Angels?

Houston Astros beat Los Angeles Angels 6-1 at Angel Stadium on September 27, 2025.

In a decisive matchup at Angel Stadium, the Houston Astros secured a commanding 6-1 victory over the Los Angeles Angels, concluding the series with a 4-2 advantage. This game showcased the Astros' offensive prowess, highlighted by multiple home runs that set the tone early and maintained pressure throughout.

The Astros, entering this game with an away record of 86-75, have had a challenging recent stretch, losing their last five games prior to this matchup. Despite this, they managed to score an average of 3.3 runs per game over their last ten outings, while allowing an average of 4.6 runs. In contrast, the Angels, with a home record of 72-89, had shown slightly better form recently, winning three out of their last ten games, including a narrow 4-3 victory against the Astros just a day prior. The Angels averaged 3.3 runs scored and allowed 5.7 runs during the same stretch.

The game began with the Astros taking an early lead in the second inning when Cole homered to center field, scoring Diaz. They extended their lead in the fourth inning with back-to-back homers from Walker and Sánchez, which put them ahead 5-0. The Angels managed to score their only run in the sixth inning when Adell doubled to left, bringing Trout home. However, Walker added another homer in the ninth inning, solidifying the Astros' dominance in this contest.

In terms of home and away performance, the Angels struggled at home with a record of 2-2 in their last four home games, while the Astros had a poor away record of 1-4 in their last five games leading up to this match. The head-to-head record favored the Astros, who have won 12 of the last 17 meetings against the Angels, including a notable 8-3 victory earlier in the season.

Injuries played a significant role in this matchup. The Angels were missing several key players, including Josh Lowe, who was day-to-day with a neck issue, and others like Gustavo Campero, Nolan Schanuel, Sam Bachman, and Yoan Moncada, who were on the injured list for various ailments. The Astros also faced injury challenges, with Brice Matthews and Carlos Correa both on the 60-day injured list, along with Mike Burrows and Brandon Walter on the 15-day injured list.

The market had set the odds reflecting the Astros' stronger season performance, though specific betting lines were not provided in the block. Conditions at Angel Stadium were typical for late September, with clear skies and a favorable atmosphere for baseball, contributing to the high-scoring nature of the game.

Viewers were treated to a display of power hitting, with four home runs in total, and the performance of Walker stood out as he not only homered twice but also contributed significantly to the Astros' offensive strategy. The Angels' pitching struggled to contain the Astros' lineup, which capitalized on mistakes and took advantage of scoring opportunities effectively.

Injury report

  • Josh LoweDay-To-DayNeckLos Angeles Angels
  • Gustavo Campero10-Day-ILHamstringLos Angeles Angels
  • Nolan Schanuel10-Day-ILSideLos Angeles Angels
  • Sam Bachman15-Day-ILForearmLos Angeles Angels
  • Yoan Moncada60-Day-ILKneeLos Angeles Angels
  • Brice Matthews60-Day-ILKneeHouston Astros
  • Mike Burrows15-Day-ILElbowHouston Astros
  • Carlos Correa60-Day-ILAnkleHouston Astros
  • Brandon Walter60-Day-ILElbowHouston Astros

Recent form

Los Angeles Angels

Last 10: 3-7Streak W13.3 scored · 5.7 allowed per game2-2 at home

  • W4-3vs Houston AstrosSep 27
  • L4-9vs Kansas City RoyalsSep 26
  • W3-2vs Kansas City RoyalsSep 25
  • L4-8vs Kansas City RoyalsSep 24
  • W3-0at Colorado RockiesSep 21
  • L6-7at Colorado RockiesSep 20
  • L2-5at Milwaukee BrewersSep 18
  • L2-9at Milwaukee BrewersSep 17
  • L2-9at Milwaukee BrewersSep 16
  • L3-5at Seattle MarinersSep 14

Houston Astros

Last 10: 4-6Streak L53.3 scored · 4.6 allowed per game1-4 away

  • L3-4at Los Angeles AngelsSep 27
  • L0-6at AthleticsSep 25
  • L1-5at AthleticsSep 24
  • L3-7vs Seattle MarinersSep 21
  • L0-4vs Seattle MarinersSep 20
  • W5-2vs Texas RangersSep 18
  • W6-5vs Texas RangersSep 17
  • W6-3vs Texas RangersSep 16
  • L3-8at Atlanta BravesSep 14
  • W6-2at Atlanta BravesSep 13

Standings

TeamGames behindLostStreakWin %Won
Houston-69W1.50771
Texas271L1.49369
Seattle574W2.47166
Athletics1786W1.38654
Los Angeles1887L2.37953

How the scoring went

  1. 2nd Inning2-0Cole homered to center (398 feet), Diaz scored.
  2. 4th Inning3-0Walker homered to left (384 feet).
  3. 4th Inning5-0Sánchez homered to right (378 feet), Cole scored.
  4. 6th Inning5-1Adell doubled to left, Trout scored.
  5. 9th Inning6-1Walker homered to left (396 feet).

Win probability

Above the line favours Los Angeles Angels, below favours Houston Astros.

Venue

  • Angel StadiumAnaheim, California
  • Attendance36487
  • OfficialsAndy Fletcher, Malachi Moore, Paul Clemons, Jansen Visconti

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.