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MLB · Final

Astros Defeat Padres 6-3 in Series Finale

Friday, August 7, 2026, 9:40 PM ET · Petco Park

Houston Astros 6, San Diego Padres 3, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Houston Astros vs San Diego Padres?

Houston Astros beat San Diego Padres 6-3 at Petco Park on August 7, 2026.

Who was favored in Houston Astros vs San Diego Padres?

San Diego Padres were the favorite at DraftKings, moneyline -108 (about 52% implied). The underdog won.

In a decisive matchup at Petco Park, the Houston Astros triumphed over the San Diego Padres with a final score of 6-3, securing the series 2-1. This victory not only showcased the Astros' strong performance but also highlighted the competitive nature of both teams, each entering the game with identical records of 60-57.

The game began with the Astros taking an early lead when Smith homered to left center in the second inning, putting Houston up 1-0. The Astros continued to build on their lead in the third inning, with Walker's single bringing in two runs, followed by Alvarez's single in the fourth, which pushed the score to 4-0. The Padres responded in the same inning with a triple from Merrill that allowed Machado to score, followed by a groundout from Sheets that brought another run home, narrowing the gap to 4-2.

The Padres, known for their recent form, had a record of 7-3 over their last ten games, averaging 5.3 runs scored and 4.1 runs allowed. Their home record stood at 3-1 during this stretch. Conversely, the Astros had been on a strong run, boasting an 8-2 record in their last ten games with an impressive scoring average of 5.8 runs and only 3.8 runs allowed. The Astros' away record in this span was 5-1, showcasing their ability to perform well on the road.

In terms of historical context, the teams had met twice earlier in the 2025 season, splitting the games with one win each. The Astros had previously won 3-2 on April 20, while the Padres took a 6-4 victory the day before.

Injuries played a role in the matchup, particularly for the Padres, who were missing several key players. Jason Adam, Miguel Andujar, Gavin Sheets, Jeremiah Estrada, and Lucas Giolito were all on the injured list, impacting the team's depth and performance. The Astros also had injury concerns, with Brice Matthews, Mike Burrows, Carlos Correa, and Brandon Walter unavailable for the game.

The betting market, as reported by DraftKings, had the Padres at -108 and the Astros at +101, with a total set at 8.5 runs. The spread was 1.5, indicating a closely contested game was anticipated.

As the game progressed, the Padres attempted to mount a comeback. Tatis Jr. hit a homer in the fifth inning, bringing the score to 4-3. However, the Astros responded with another run in the sixth when Smith homered again, extending their lead to 5-3. In the eighth inning, Peña's groundout allowed Smith to score, finalizing the score at 6-3.

The conditions at Petco Park were conducive for baseball, and fans witnessed a competitive game filled with notable plays and strategic moments. The Astros' ability to capitalize on scoring opportunities ultimately led to their victory, while the Padres fought hard but fell short.

This game not only showcased the talent on both rosters but also underscored the importance of depth and health as the season progresses. With the Astros now having won the series, both teams will look to build on their performances in the coming games.

Odds

BookSpreadTotalMoneyline
DraftKingsSD -108 8.5 o -116 / u -104 Houston Astros +101 · San Diego Padres -108

What these prices pay on $100 · What these numbers mean

Injury report

  • Jason Adam60-Day-ILShoulderSan Diego Padres
  • Miguel Andujar10-Day-ILWristSan Diego Padres
  • Gavin Sheets10-Day-ILFootSan Diego Padres
  • Jeremiah Estrada15-Day-ILShoulderSan Diego Padres
  • Lucas Giolito60-Day-ILElbowSan Diego Padres
  • Brice Matthews60-Day-ILKneeHouston Astros
  • Mike Burrows15-Day-ILElbowHouston Astros
  • Carlos Correa60-Day-ILAnkleHouston Astros
  • Brandon Walter60-Day-ILElbowHouston Astros

Recent form

San Diego Padres

Last 10: 7-3Streak W15.3 scored · 4.1 allowed per game3-1 at home

  • W5-1at Arizona DiamondbacksAug 7
  • L4-10at Arizona DiamondbacksAug 6
  • W9-4at Arizona DiamondbacksAug 5
  • L1-5at Arizona DiamondbacksAug 4
  • W6-5vs San Francisco GiantsAug 2
  • W7-0vs San Francisco GiantsAug 1
  • L1-4vs San Francisco GiantsJul 31
  • W8-7vs Colorado RockiesJul 29
  • W5-3at Miami MarlinsJul 26
  • W7-2at Miami MarlinsJul 25

Houston Astros

Last 10: 8-2Streak W15.8 scored · 3.8 allowed per game5-1 away

  • W7-2vs Toronto Blue JaysAug 5
  • L1-3vs Toronto Blue JaysAug 4
  • W7-3vs Texas RangersAug 2
  • W11-2vs Texas RangersAug 1
  • W7-4at Los Angeles AngelsJul 30
  • W3-2at Los Angeles AngelsJul 29
  • W6-4at Los Angeles AngelsJul 28
  • L3-12at Chicago White SoxJul 26
  • W4-1at Chicago White SoxJul 25
  • W9-5at Chicago White SoxJul 24

Standings

TeamGames behindLostStreakWin %Won
Houston-69W2.51172
Texas271W1.49670
Seattle675L1.46866
Athletics1786W2.39055
Los Angeles18.587L2.37953
Los Angeles-57W1.59383
Arizona9.567W1.52574
San Diego1067L2.52173
San Francisco25.583L1.41158
Colorado2986W2.38654

How the scoring went

  1. 2nd Inning1-0Smith homered to left center (383 feet).
  2. 3rd Inning3-0Walker singled to center, Alvarez scored and Paredes scored, Altuve to second.
  3. 4th Inning4-0Alvarez singled to right, Meyers scored, Peña to third.
  4. 4th Inning4-1Merrill tripled to right, Machado scored.
  5. 4th Inning4-2Sheets grounded into double play, first to shortstop, Merrill scored, Campusano out at second.
  6. 5th Inning4-3Tatis Jr. homered to left (400 feet).
  7. 6th Inning5-3Smith homered to left (392 feet).
  8. 8th Inning6-3Peña grounded into double play, second to first to shortstop, Smith scored, Meyers out at second.

Win probability

Above the line favours San Diego Padres, below favours Houston Astros.

Venue

  • Petco ParkSan Diego, California
  • Attendance40958
  • OfficialsJim Wolf, Alex Mackay, Jacob Metz, Roberto Ortiz

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.