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MLB · Final

Cardinals Secure Series Win Against Royals 4-2

Saturday, May 16, 2026, 2:15 PM ET · Busch Stadium

St. Louis Cardinals 4, Kansas City Royals 2, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Kansas City Royals vs St. Louis Cardinals?

St. Louis Cardinals beat Kansas City Royals 4-2 at Busch Stadium on May 16, 2026.

Who was favored in Kansas City Royals vs St. Louis Cardinals?

St. Louis Cardinals were the favorite at DraftKings, moneyline -114 (about 53% implied). The favorite won.

In a decisive matchup at Busch Stadium, the St. Louis Cardinals triumphed over the Kansas City Royals with a final score of 4-2, clinching the series 2-1. This victory is particularly significant as it highlights the Cardinals' ability to capitalize on home-field advantage, maintaining a strong record of 27-18 for the season.

The Cardinals entered this game with a mixed recent form, having recorded a 5-4-1 record in their last ten games. They had an average of 3.4 runs scored per game while allowing only 2.9. However, they were on a one-game losing streak, having lost to the Oakland Athletics just two days prior. In contrast, the Royals have struggled recently, with a 4-6 record in their last ten games and a current four-game losing streak. They averaged 4.1 runs scored but allowed 4.4 runs, indicating a need for improvement on the mound.

When considering home versus away performance, the Cardinals have shown resilience at home with a record of 2-2 in their last four home games. The Royals, on the other hand, have struggled significantly on the road, losing all three of their most recent away games. This disparity in performance likely played a role in the Cardinals' confidence heading into this matchup.

Historically, the Cardinals have had the upper hand in recent meetings with the Royals, holding a record of 3-2-1 against them in their last six encounters. In their previous matchups last season, the Cardinals secured a win, a draw, and a loss, suggesting a competitive rivalry.

In terms of injuries, the Cardinals faced several challenges, including Everson Pereira and Masyn Winn on the 10-Day Injured List due to hand and thumb injuries, respectively. Ramon Urias was listed as day-to-day with an arm issue, while Andre Pallante and JJ Wetherholt were also on the injured list. The Royals were not without their own injury woes, with Maikel Garcia on the 10-Day IL due to a hamstring injury and Connor Seabold on the 60-Day IL for a lat issue, among others.

The betting market, provided by DraftKings, had the Cardinals favored at -114, with a spread of 1.5 and a total set at 9.0. The odds for the over were -112.0, while the under was at -108.0, reflecting a competitive outlook for the game.

The conditions at Busch Stadium were favorable for baseball, contributing to an engaging atmosphere for fans and players alike. Viewers were treated to a series of notable scoring plays, beginning with a sacrifice fly from Burleson in the first inning that brought Herrera home. The Royals tied the game in the fifth inning when Pasquantino singled to center, scoring Garcia. However, the Cardinals responded effectively, scoring three runs in the fifth inning, including another sacrifice fly, this time from Winn, and a critical error that allowed Burleson to reach second base safely.

The game concluded with a late home run from Caglianone for the Royals in the ninth inning, but it was not enough to change the outcome. The Cardinals' defense held strong, ensuring their victory and solidifying their position in the league standings. This game not only showcased the Cardinals' home dominance but also highlighted the ongoing struggles of the Royals as they seek to turn their season around.

Odds

BookSpreadTotalMoneyline
DraftKingsSTL -114 9 o -112 / u -108 Kansas City Royals -106 · St. Louis Cardinals -114

What these prices pay on $100 · What these numbers mean

Injury report

  • Everson Pereira10-Day-ILHandSt. Louis Cardinals
  • Ramon UriasDay-To-DayArmSt. Louis Cardinals
  • Masyn Winn10-Day-ILThumbSt. Louis Cardinals
  • Andre Pallante15-Day-ILElbowSt. Louis Cardinals
  • JJ Wetherholt10-Day-ILWristSt. Louis Cardinals
  • Maikel Garcia10-Day-ILHamstringKansas City Royals
  • Connor Seabold60-Day-ILLatKansas City Royals
  • Tony Gonsolin15-Day-ILElbowKansas City Royals
  • James McArthur60-Day-ILElbowKansas City Royals
  • Beck Way15-Day-ILShoulderKansas City Royals

Recent form

St. Louis Cardinals

Last 10: 5-4-1Streak L13.4 scored · 2.9 allowed per game2-2 at home

  • L2-6at AthleticsMay 14
  • W6-4at AthleticsMay 13
  • L2-3at San Diego PadresMay 10
  • W6-0at San Diego PadresMay 9
  • W2-1at San Diego PadresMay 8
  • L2-6vs Milwaukee BrewersMay 6
  • D0-0vs Milwaukee BrewersMay 5
  • W6-3vs Milwaukee BrewersMay 4
  • L1-4vs Los Angeles DodgersMay 3
  • W7-2vs Los Angeles DodgersMay 2

Kansas City Royals

Last 10: 4-6Streak L44.1 scored · 4.4 allowed per game0-3 away

  • L2-6at Chicago White SoxMay 14
  • L5-6at Chicago White SoxMay 13
  • L5-6at Chicago White SoxMay 12
  • L3-6vs Detroit TigersMay 10
  • W5-1vs Detroit TigersMay 9
  • W4-3vs Detroit TigersMay 8
  • L5-8vs Cleveland GuardiansMay 7
  • L1-3vs Cleveland GuardiansMay 6
  • W5-3vs Cleveland GuardiansMay 5
  • W6-2vs Cleveland GuardiansMay 4

Standings

TeamGames behindLostStreakWin %Won
Chicago-66L1.52573
Cleveland369L1.50470
Minnesota6.573L1.47967
Detroit975W1.46064
Kansas City11.578L3.44362
Milwaukee-53W2.62187
Chicago962L2.55778
St. Louis1770W2.50070
Pittsburgh1972L1.48668
Cincinnati2073W2.47967

How the scoring went

  1. 1st Inning0-1Burleson hit sacrifice fly to right, Herrera scored.
  2. 5th Inning1-1Pasquantino singled to center, Garcia scored.
  3. 5th Inning1-2Scott II grounded into fielder's choice to first, Saggese scored, Church third.
  4. 5th Inning1-3Winn hit sacrifice fly to center, Church scored.
  5. 8th Inning1-4Burleson singled to left, Winn scored on error, Burleson safe at second on throwing error by catcher Díaz, Herrera safe at third on error.
  6. 9th Inning2-4Caglianone homered to right (428 feet).

Win probability

Above the line favours St. Louis Cardinals, below favours Kansas City Royals.

Venue

  • Busch StadiumSt. Louis, Missouri
  • Attendance32379
  • OfficialsRyan Additon, Ryan Wills, Lance Barksdale, Will Little

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.