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MLB · Final

Padres Sweep Twins with 6-2 Victory at Petco Park

Friday, August 21, 2026, 9:40 PM ET · Petco Park

San Diego Padres 6, Minnesota Twins 2, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Minnesota Twins vs San Diego Padres?

San Diego Padres beat Minnesota Twins 6-2 at Petco Park on August 21, 2026.

Who was favored in Minnesota Twins vs San Diego Padres?

San Diego Padres were the favorite at DraftKings, moneyline -119 (about 54% implied). The favorite won.

In a decisive matchup at Petco Park, the San Diego Padres secured a 6-2 victory over the Minnesota Twins, completing a three-game sweep of the series. This win marks a significant achievement for the Padres, who have shown resilience and skill throughout the series, ultimately finishing with a 3-0 record against the Twins.

The Padres entered this game with a home record of 69-60, while the Twins had an away record of 63-66. The Padres' recent form had been mixed, with a record of 6-4 over their last ten games, but they were coming off a loss to the New York Mets just days prior. Their scoring average at home was 4.5 runs per game, while they allowed an average of 3.1 runs. In contrast, the Twins had a balanced record of 5-5 in their last ten games, riding a three-game winning streak into this contest. They averaged 4.2 runs scored but allowed 4.9 runs per game.

In terms of home and away performance, the Padres had a strong home record of 3-1 in their last four games, while the Twins struggled on the road, with a record of 0-1 in their last away game. The recent head-to-head meetings between these two teams had favored the Twins, who had won both encounters in the previous season, but the Padres turned the tide in this series.

Injuries played a role in the matchup, particularly for the Padres, who were missing several key players. Jason Adam was on the 60-day injured list due to a shoulder issue, while Miguel Andujar and Gavin Sheets were both on the 10-day injured list with wrist and foot injuries, respectively. Additionally, Jeremiah Estrada and Lucas Giolito were also sidelined with shoulder and elbow injuries. The Twins faced their own injury challenges, with Byron Buxton and Austin Martin on the 10-day injured list due to hip and hamstring injuries, while Joe Ryan, Mike Paredes, and Mick Abel were on the 15-day and 60-day injured lists with various ailments.

The betting market reflected the Padres' status as slight favorites, with DraftKings pricing them at -119 on the money line, while the Twins were at +111. The spread was set at -1.5 for the Padres, with a total of 8.0 runs for the game. The odds for the over were -118, and for the under, -102.

The game conditions were favorable for baseball, contributing to an engaging atmosphere at Petco Park. Fans were treated to a thrilling performance, particularly from Padres' players. The scoring began in the first inning when Ty France homered to left center, bringing in Manny Machado and putting the Padres ahead 2-0. The Twins responded in the fourth inning with a triple from Clemens, allowing Byron Buxton and Bell to score, leveling the game at 2-2.

However, the Padres regained control in the fifth inning with a series of hits that led to four runs. Fernando Tatis Jr. singled to right, bringing in Hays, followed by Rengifo's single that scored Cronenworth, and Machado's single that brought Tatis Jr. home. France capped off the inning with a sacrifice fly that allowed Rengifo to score, extending the Padres' lead to 6-2.

In the end, the Padres demonstrated their offensive prowess and solid pitching, securing a comfortable win and showcasing their potential as they head deeper into the season. This victory not only solidified their dominance over the Twins in this series but also provided a much-needed boost to their confidence as they continue to compete in the league.

Odds

BookSpreadTotalMoneyline
DraftKingsSD -119 8 o -118 / u -102 Minnesota Twins +111 · San Diego Padres -119

What these prices pay on $100 · What these numbers mean

Injury report

  • Jason Adam60-Day-ILShoulderSan Diego Padres
  • Miguel Andujar10-Day-ILWristSan Diego Padres
  • Gavin Sheets10-Day-ILFootSan Diego Padres
  • Jeremiah Estrada15-Day-ILShoulderSan Diego Padres
  • Lucas Giolito60-Day-ILElbowSan Diego Padres
  • Byron Buxton10-Day-ILHipMinnesota Twins
  • Austin Martin10-Day-ILHamstringMinnesota Twins
  • Joe Ryan15-Day-ILLower BodyMinnesota Twins
  • Mike Paredes60-Day-ILObliqueMinnesota Twins
  • Mick Abel60-Day-ILElbowMinnesota Twins

Recent form

San Diego Padres

Last 10: 6-4Streak L14.5 scored · 3.1 allowed per game3-1 at home

  • L2-4at New York MetsAug 19
  • W5-2at New York MetsAug 18
  • L1-2at New York MetsAug 17
  • W5-0at Cleveland GuardiansAug 16
  • L1-6at Cleveland GuardiansAug 15
  • W7-5at Cleveland GuardiansAug 14
  • W11-2vs Milwaukee BrewersAug 12
  • W3-2vs Milwaukee BrewersAug 11
  • W7-2vs Houston AstrosAug 10
  • L3-6vs Houston AstrosAug 8

Minnesota Twins

Last 10: 5-5Streak W34.2 scored · 4.9 allowed per game0-1 away

  • W6-4vs Atlanta BravesAug 19
  • W4-1vs Atlanta BravesAug 18
  • W4-2vs Atlanta BravesAug 17
  • L5-7vs Philadelphia PhilliesAug 16
  • L1-9vs Philadelphia PhilliesAug 15
  • L1-7vs Philadelphia PhilliesAug 13
  • W7-5vs Baltimore OriolesAug 12
  • L2-5vs Baltimore OriolesAug 11
  • W9-5vs Baltimore OriolesAug 10
  • L3-4at Milwaukee BrewersAug 9

Standings

TeamGames behindLostStreakWin %Won
Chicago-67L2.52173
Cleveland370L2.50070
Minnesota673L1.47967
Detroit8.575W1.46064
Kansas City10.578W1.44763
Los Angeles-57W1.59383
Arizona9.567W1.52574
San Diego1067L2.52173
San Francisco25.583L1.41158
Colorado2986W2.38654

How the scoring went

  1. 1st Inning0-2France homered to left center (421 feet), Machado scored.
  2. 4th Inning2-2Clemens tripled to right, Buxton scored and Bell scored.
  3. 5th Inning2-3Tatis Jr. singled to right, Hays scored, Cronenworth to third.
  4. 5th Inning2-4Rengifo singled to left, Cronenworth scored, Tatis Jr. to second.
  5. 5th Inning2-5Machado singled to right, Tatis Jr. scored, Rengifo to third.
  6. 5th Inning2-6France hit sacrifice fly to right, Rengifo scored, Machado to second.

Win probability

Above the line favours San Diego Padres, below favours Minnesota Twins.

Venue

  • Petco ParkSan Diego, California
  • Attendance44293
  • OfficialsBrian Walsh, Chad Fairchild, Bill Miller, Chad Whitson

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.