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MLB · Final

Padres Dominate Pirates in 5-0 Victory

Monday, April 6, 2026, 6:40 PM ET · PNC Park

San Diego Padres 5, Pittsburgh Pirates 0, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won San Diego Padres vs Pittsburgh Pirates?

San Diego Padres beat Pittsburgh Pirates 5-0 at PNC Park on April 6, 2026.

Who was favored in San Diego Padres vs Pittsburgh Pirates?

Pittsburgh Pirates were the favorite at DraftKings, moneyline -143 (about 59% implied). The underdog won.

The San Diego Padres delivered a commanding performance against the Pittsburgh Pirates, winning decisively 5-0 at PNC Park. This result capped off a three-game series in which the Padres secured two victories, winning the series 2-1. The Pirates entered the game with a home record of 6-4 and were riding a five-game winning streak, showcasing a recent average of 4.6 runs scored per game while allowing 3.8. In contrast, the Padres had a balanced away record of 5-5, averaging 3.7 runs scored and allowing 4.3 runs per game.

In this matchup, the Padres opened the scoring in the fourth inning when Nick Castellanos doubled to left field, bringing home Manny Machado. The fifth inning saw the Padres extend their lead with a ground rule double from Merrill, which scored Ramón Laureano and advanced Fernando Tatis Jr. to third base. Machado then grounded out to first base, allowing Tatis Jr. to score, making it 3-0. The sixth inning featured a double from Jake Cronenworth that brought in Fermin, and Laureano capped off the scoring in the eighth with another double, scoring Fermin.

The Pirates struggled offensively throughout the game, failing to score any runs against the Padres' pitching staff. This loss was particularly disappointing for the Pirates, who had been performing well at home, winning their last five games before this contest. Their home record now stands at 3-1 in their last four games at PNC Park.

In terms of player availability, the Pirates were significantly impacted by injuries, with several key players on the injured list, including Konnor Griffin, Ryan O'Hearn, and Mitch Keller. The Padres also faced injury challenges, with Jason Adam and Lucas Giolito on the 60-day injured list, among others. These absences undoubtedly influenced both teams' performances in this series.

The betting odds from DraftKings indicated the Pirates as the favorites at -143, with a spread of -1.5 and a total set at 8.5. The odds reflected the Pirates' strong home form and recent success, but the Padres' victory highlighted the unpredictability of baseball.

Overall, the Padres' victory was a testament to their offensive capabilities and pitching strength, while the Pirates will need to regroup and address their injury concerns as they move forward in the season.

Odds

BookSpreadTotalMoneyline
DraftKingsPIT -143 8.5 o -110 / u -110 San Diego Padres +119 · Pittsburgh Pirates -143

What these prices pay on $100 · What these numbers mean

Injury report

  • Konnor Griffin60-Day-ILFingerPittsburgh Pirates
  • Ryan O'Hearn10-Day-ILQuadricepsPittsburgh Pirates
  • Kirby Yates15-Day-ILShoulderPittsburgh Pirates
  • Mitch Keller60-Day-ILArmPittsburgh Pirates
  • Endy Rodriguez60-Day-ILHipPittsburgh Pirates
  • Jason Adam60-Day-ILShoulderSan Diego Padres
  • Miguel Andujar10-Day-ILWristSan Diego Padres
  • Gavin Sheets10-Day-ILFootSan Diego Padres
  • Jeremiah Estrada15-Day-ILShoulderSan Diego Padres
  • Lucas Giolito60-Day-ILElbowSan Diego Padres

Recent form

Pittsburgh Pirates

Last 10: 6-4Streak W54.6 scored · 3.8 allowed per game3-0 at home

  • W8-2vs Baltimore OriolesApr 5
  • W3-2vs Baltimore OriolesApr 4
  • W5-4vs Baltimore OriolesApr 3
  • W8-3at Cincinnati RedsApr 1
  • W8-3at Cincinnati RedsMar 31
  • L0-2at Cincinnati RedsMar 30
  • W4-3at New York MetsMar 29
  • L2-4at New York MetsMar 28
  • L7-11at New York MetsMar 26
  • L1-4at Atlanta BravesSep 28

San Diego Padres

Last 10: 5-5Streak W23.7 scored · 4.3 allowed per game2-1 away

  • W8-6at Boston Red SoxApr 5
  • W3-2at Boston Red SoxApr 4
  • L2-5at Boston Red SoxApr 3
  • L3-9vs San Francisco GiantsApr 1
  • L2-3vs San Francisco GiantsMar 31
  • W3-0vs Detroit TigersMar 29
  • L2-5vs Detroit TigersMar 28
  • L2-8vs Detroit TigersMar 26
  • W5-1vs Arizona DiamondbacksSep 28
  • W7-4vs Arizona DiamondbacksSep 27

Standings

TeamGames behindLostStreakWin %Won
Los Angeles-57L2.59082
Arizona967W1.52574
San Diego9.567L2.52173
San Francisco24.582W1.41458
Colorado28.586W2.38654
Milwaukee-53W2.62187
Chicago962L2.55778
St. Louis1770W2.50070
Pittsburgh1972L1.48668
Cincinnati2073W2.47967

How the scoring went

  1. 4th Inning1-0Castellanos doubled to left, Machado scored, Sheets to third.
  2. 5th Inning2-0Merrill hit a ground rule double, Laureano scored, Tatis Jr. to third.
  3. 5th Inning3-0Machado grounded out to first, Tatis Jr. scored, Merrill to third.
  4. 6th Inning4-0Cronenworth doubled to right, Fermin scored.
  5. 8th Inning5-0Laureano doubled to right, Fermin scored.

Win probability

Above the line favours Pittsburgh Pirates, below favours San Diego Padres.

Venue

  • PNC ParkPittsburgh, Pennsylvania
  • Attendance8446
  • OfficialsTripp Gibson, Ryan Blakney, Nick Mahrley, Marvin Hudson

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.