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MLB · Final

Mariners Dominate Astros in 10-2 Victory

Tuesday, May 12, 2026, 8:10 PM ET · Daikin Park

Seattle Mariners 10, Houston Astros 2, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Seattle Mariners vs Houston Astros?

Seattle Mariners beat Houston Astros 10-2 at Daikin Park on May 12, 2026.

Who was favored in Seattle Mariners vs Houston Astros?

Seattle Mariners were the favorite at DraftKings, moneyline -180 (about 64% implied). The favorite won.

The Seattle Mariners delivered a commanding performance against the Houston Astros, winning 10-2 at Daikin Park. This victory marks the Mariners' continued dominance over the Astros in their recent series, as they have now won three out of four matchups in this season's encounters. The Mariners' triumph was highlighted by a strong offensive display, with key contributions from players like Randy Arozarena and Josh Canzone.

In terms of recent form, the Astros have struggled, recording a 4-6 record over their last ten games and currently on a three-game losing streak. They have averaged 3.0 runs scored per game while allowing 3.7 runs during this stretch. In their last game prior to this matchup, the Astros lost to the Mariners 1-3, further emphasizing their difficulties against this opponent. At home, the Astros have a record of 16-27, with a home record of 1-2 in their last three games.

Conversely, the Mariners have been more consistent, posting a 5-5 record in their last ten games and coming off a win against the Astros. They have averaged 4.4 runs scored per game while allowing 3.8 runs. Seattle's recent form includes a victory against the Chicago White Sox, and they have a better away record of 21-22 compared to the Astros' home struggles.

In their head-to-head meetings, the Mariners have historically performed well against the Astros, holding a 10-3 record in their last 13 matchups. This season alone, the Mariners have won three of the four encounters, including the last two games. The Astros have not won a game against the Mariners since April 11, 2026.

Injuries have also played a significant role in the Astros' struggles. They are missing key players, including Brice Matthews (60-Day IL, knee), Mike Burrows (15-Day IL, elbow), Carlos Correa (60-Day IL, ankle), and Brandon Walter (60-Day IL, elbow). The Mariners are also dealing with injuries, including Brendan Donovan (7-Day IL, concussion), Cole Wilcox (15-Day IL, oblique), Matt Brash (60-Day IL, lat), Will Wilson (60-Day IL, thumb), and Emerson Hancock (15-Day IL, groin).

The betting market, as provided by DraftKings, favored the Mariners with odds of SEA -180, indicating a strong expectation for their performance. The spread was set at 1.5, with a total of 9.0 runs for the game. The over odds were listed at 101.0, while the under odds were at -121.0. The moneyline for the home team, the Astros, was at 148.0, while the Mariners were at -180.

Game conditions were favorable for a high-scoring affair, and the Mariners took full advantage. They scored consistently throughout the game, starting with Arozarena's homer in the second inning, which set the tone. The Mariners continued to build their lead with a strong fourth inning, highlighted by Canzone's grand slam that brought in four runs. The Astros managed to score two runs but were unable to keep pace with the Mariners' offensive onslaught.

Viewers should have noted the Mariners' ability to capitalize on scoring opportunities, as they executed well in crucial moments, including multiple hits with runners in scoring position. The Astros, on the other hand, struggled to maintain momentum and failed to convert their chances into significant runs.

In summary, the Mariners' 10-2 victory over the Astros underscores their current superiority in this matchup, as they continue to build on their successful season while the Astros face ongoing challenges.

Odds

BookSpreadTotalMoneyline
DraftKingsSEA -180 9 o +101 / u -121 Seattle Mariners -180 · Houston Astros +148

What these prices pay on $100 · What these numbers mean

Injury report

  • Brice Matthews60-Day-ILKneeHouston Astros
  • Mike Burrows15-Day-ILElbowHouston Astros
  • Carlos Correa60-Day-ILAnkleHouston Astros
  • Brandon Walter60-Day-ILElbowHouston Astros
  • Brendan Donovan7-Day ILConcussionSeattle Mariners
  • Cole Wilcox15-Day-ILObliqueSeattle Mariners
  • Matt Brash60-Day-ILLatSeattle Mariners
  • Will Wilson60-Day-ILThumbSeattle Mariners
  • Emerson Hancock15-Day-ILGroinSeattle Mariners

Recent form

Houston Astros

Last 10: 4-6Streak L33 scored · 3.7 allowed per game1-2 at home

  • L1-3vs Seattle MarinersMay 12
  • L0-5at Cincinnati RedsMay 10
  • L1-3at Cincinnati RedsMay 9
  • W10-0at Cincinnati RedsMay 8
  • W2-1vs Los Angeles DodgersMay 6
  • L3-8vs Los Angeles DodgersMay 5
  • W3-1at Boston Red SoxMay 3
  • W6-3at Boston Red SoxMay 2
  • L1-3at Boston Red SoxMay 1
  • L3-10at Baltimore OriolesApr 30

Seattle Mariners

Last 10: 5-5Streak W14.4 scored · 3.8 allowed per game4-2 away

  • W3-1at Houston AstrosMay 12
  • L1-2at Chicago White SoxMay 10
  • L1-6at Chicago White SoxMay 9
  • W12-8at Chicago White SoxMay 8
  • L2-3vs Atlanta BravesMay 6
  • W5-4vs Atlanta BravesMay 5
  • L2-3vs Kansas City RoyalsMay 3
  • L6-7vs Kansas City RoyalsMay 2
  • W5-3at Minnesota TwinsApr 29
  • W7-1at Minnesota TwinsApr 28

Standings

TeamGames behindLostStreakWin %Won
Houston-69W1.50771
Texas271L1.49369
Seattle574W2.47166
Athletics1786W1.38654
Los Angeles1887L2.37953

How the scoring went

  1. 2nd Inning2-0Arozarena homered to left (369 feet), Raleigh scored.
  2. 2nd Inning2-1Shewmake singled to center, Dezenzo scored.
  3. 3rd Inning2-2Walker doubled to left, Altuve scored, Alvarez to third.
  4. 4th Inning6-2Canzone homered to right (381 feet), Arozarena scored, Raley scored and Crawford scored.
  5. 5th Inning7-2Crawford singled to left, Arozarena scored.
  6. 7th Inning8-2Arozarena doubled to right, Raleigh scored.
  7. 9th Inning9-2Crawford walked, Raleigh scored, Raley to second, Arozarena to third.
  8. 9th Inning10-2Canzone hit sacrifice fly to right, Arozarena scored, Raley to third.

Win probability

Above the line favours Houston Astros, below favours Seattle Mariners.

Venue

  • Daikin ParkHouston, Texas
  • Attendance28829
  • OfficialsJim Wolf, Roberto Ortiz, Alex Mackay, Willie Traynor

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.