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MLB · Final

Cubs Dominate Cardinals in 12-1 Victory at Wrigley Field

Friday, September 26, 2025, 2:20 PM ET · Wrigley Field

Chicago Cubs 12, St. Louis Cardinals 1, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won St. Louis Cardinals vs Chicago Cubs?

Chicago Cubs beat St. Louis Cardinals 12-1 at Wrigley Field on September 26, 2025.

The Chicago Cubs delivered a commanding performance against the St. Louis Cardinals, winning the game 12-1 at Wrigley Field. This victory not only showcased the Cubs' offensive prowess but also solidified their dominance over the Cardinals this season, with the Cubs winning the series 5-1. The Cubs entered this game with a home record of 90-70, while the Cardinals finished the season at 78-82.

In terms of recent form, the Cubs have been inconsistent, holding a record of 5-5 in their last ten games, but they managed to snap a four-game losing streak with this win, averaging 4.4 runs scored and allowing 3.5 runs in their last ten outings. They had previously faced the New York Mets, securing a 10-3 victory just a day before this match. At home, the Cubs have a record of 2-1 in their last three games, while their away record stands at 3-4 in the same span.

The Cardinals, on the other hand, have also been 5-5 in their last ten games, but they are currently on a one-game losing streak. They averaged 5.1 runs scored and 5.3 runs allowed in their recent games. Their last outing resulted in a narrow 4-3 loss to the San Francisco Giants, and they have struggled on the road with a 2-3 record in their last five away games.

Historically, the Cubs and Cardinals have had a competitive rivalry, with the Cubs holding an overall record of 8-10-1 against the Cardinals in their last few meetings spanning the 2024 and 2025 seasons. The most recent matchups saw the Cubs winning decisively at home, including an 11-0 victory on July 6, 2025.

In terms of injuries, the Cubs are dealing with several key players on the injured list. Edward Cabrera is on the 15-Day Injured List due to a finger issue, and Shelby Miller is on the 60-Day Injured List with an elbow injury. Jacob Webb and Pedro Ramirez are both day-to-day with arm and back issues, respectively, while Gavin Hollowell is also on the 15-Day Injured List with a shoulder injury. The Cardinals have their own injury concerns, with Everson Pereira on the 10-Day Injured List due to a hand injury, and Ramon Urias day-to-day with an arm issue. Additionally, Masyn Winn is on the 10-Day Injured List with a thumb injury, Andre Pallante is on the 15-Day Injured List with an elbow injury, and JJ Wetherholt is on the 10-Day Injured List with a wrist injury.

The market had priced the Cubs as heavy favorites, reflecting their strong home record and recent form, with a home win probability of 1.0.

Weather conditions at Wrigley Field were conducive to a high-scoring game, and the Cubs took full advantage. The scoring began in the fourth inning when Crow-Armstrong homered to right center, bringing Tucker home and putting the Cubs ahead 3-0. The fifth inning saw Busch hit a homer to center, extending the lead to 4-0. The Cardinals managed to get on the board in the seventh inning with a single from Walker, scoring Gorman, but the Cubs responded emphatically.

The seventh inning was particularly explosive for the Cubs, as they scored several runs, including a triple from Shaw that brought Swanson home, a double from Busch that scored Shaw, and an infield single from Happ that allowed Busch to cross the plate. Suzuki capped off the scoring for the Cubs with a three-run homer to left center, bringing Hoerner and Happ home, pushing the score to 11-1. The final run for the Cubs came in the eighth inning when Alcántara singled to right, scoring Ballesteros and sealing the game at 12-1.

Overall, this game was a testament to the Cubs' offensive capabilities and their ability to capitalize on the Cardinals' struggles, particularly in the latter innings. Fans watching the game were treated to a display of power hitting and strategic plays that highlighted the Cubs' strengths as they head into the postseason.

Injury report

  • Edward Cabrera15-Day-ILFingerChicago Cubs
  • Shelby Miller60-Day-ILElbowChicago Cubs
  • Jacob WebbDay-To-DayArmChicago Cubs
  • Pedro RamirezDay-To-DayBackChicago Cubs
  • Gavin Hollowell15-Day-ILShoulderChicago Cubs
  • Everson Pereira10-Day-ILHandSt. Louis Cardinals
  • Ramon UriasDay-To-DayArmSt. Louis Cardinals
  • Masyn Winn10-Day-ILThumbSt. Louis Cardinals
  • Andre Pallante15-Day-ILElbowSt. Louis Cardinals
  • JJ Wetherholt10-Day-ILWristSt. Louis Cardinals

Recent form

Chicago Cubs

Last 10: 5-5Streak W14.4 scored · 3.5 allowed per game2-1 at home

  • W10-3vs New York MetsSep 25
  • L7-9vs New York MetsSep 23
  • L0-1at Cincinnati RedsSep 21
  • L3-6at Cincinnati RedsSep 20
  • L4-7at Cincinnati RedsSep 19
  • L0-1at Cincinnati RedsSep 18
  • W8-4at Pittsburgh PiratesSep 17
  • W4-1at Pittsburgh PiratesSep 16
  • W4-0at Pittsburgh PiratesSep 15
  • W4-3vs Tampa Bay RaysSep 14

St. Louis Cardinals

Last 10: 5-5Streak L15.1 scored · 5.3 allowed per game2-3 away

  • L3-4at San Francisco GiantsSep 25
  • W9-8at San Francisco GiantsSep 24
  • W6-5at San Francisco GiantsSep 23
  • W5-1vs Milwaukee BrewersSep 21
  • W7-1vs Milwaukee BrewersSep 20
  • L2-6vs Cincinnati RedsSep 17
  • W3-0vs Cincinnati RedsSep 16
  • L6-11vs Cincinnati RedsSep 15
  • L8-9at Milwaukee BrewersSep 14
  • L2-8at Milwaukee BrewersSep 13

Standings

TeamGames behindLostStreakWin %Won
Milwaukee-53W2.62187
Chicago962L2.55778
St. Louis1770W2.50070
Pittsburgh1972L1.48668
Cincinnati2073W2.47967

How the scoring went

  1. 1st Inning0-1Hoerner homered to center (412 feet).
  2. 4th Inning0-3Crow-Armstrong homered to right center (396 feet), Tucker scored.
  3. 5th Inning0-4Busch homered to center (414 feet).
  4. 7th Inning1-4Walker singled to left, Gorman scored, Saggese to second.
  5. 7th Inning1-5Shaw tripled to left, Swanson scored.
  6. 7th Inning1-6Busch doubled to right, Shaw scored.
  7. 7th Inning1-7Happ reached on infield single to shortstop, Busch scored, Hoerner to second.
  8. 7th Inning1-11Suzuki homered to left center (392 feet), Hoerner scored, Happ scored and Tucker scored.
  9. 8th Inning1-12Alcántara singled to right, Ballesteros scored.

Win probability

Above the line favours Chicago Cubs, below favours St. Louis Cardinals.

Venue

  • Wrigley FieldChicago, Illinois
  • Attendance35611
  • OfficialsBill Miller, Roberto Ortiz, Ben May, Chad Fairchild

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.