Padres Edge Cardinals in Extra Innings Thriller
Sunday, May 10, 2026, 4:10 PM ET · Petco Park
San Diego Padres 3, St. Louis Cardinals 2, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.
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Quick answers
Who won St. Louis Cardinals vs San Diego Padres?
San Diego Padres beat St. Louis Cardinals 3-2 at Petco Park on May 10, 2026.
Who was favored in St. Louis Cardinals vs San Diego Padres?
San Diego Padres were the favorite at DraftKings, moneyline -137 (about 58% implied). The favorite won.
In a tightly contested matchup at Petco Park, the San Diego Padres triumphed over the St. Louis Cardinals with a final score of 3-2 after ten innings. This victory allowed the Padres to take a crucial lead in the series, now holding a 3-2 advantage against the Cardinals in their recent encounters.
Both teams entered this game with strong records, the Padres boasting a home record of 24-16, while the Cardinals had an away record of 23-17. However, the recent form of each team painted a different picture. The Padres had struggled in their last ten games, posting a record of 3-7, including a two-game losing streak. They averaged 4.0 runs scored per game but allowed 5.9 runs, indicating defensive vulnerabilities. In contrast, the Cardinals were riding a wave of momentum, with a record of 7-2-1 in their last ten games, including a two-game winning streak. They averaged 5.0 runs scored while allowing only 3.2 runs, showcasing a more balanced performance.
At home, the Padres had a record of 1-5 in their last six games, while the Cardinals were 5-0 in their last five away games, emphasizing the disparity in form. The matchup was particularly intriguing as it was the fifth meeting of the season between these two teams, with the series tied at 2-2 prior to this game. The previous encounters had seen the Padres struggle, losing both games leading up to this one.
In terms of injuries, the Padres were significantly impacted, with several key players on the injured list. Jason Adam was on the 60-day injured list due to a shoulder issue, while Miguel Andujar and Gavin Sheets were both on the 10-day injured list with wrist and foot injuries, respectively. Additionally, Jeremiah Estrada was on the 15-day injured list with a shoulder issue, and Lucas Giolito was also on the 60-day injured list due to an elbow injury. The Cardinals faced their own injury challenges, with Everson Pereira on the 10-day injured list due to a hand injury and Masyn Winn also on the 10-day injured list with a thumb issue. Ramon Urias was listed as day-to-day with an arm injury, adding to the uncertainty for the Cardinals.
The betting market reflected the competitive nature of this fixture, with DraftKings pricing the Padres at -137 on the money line, while the Cardinals were at +114. The spread was set at -1.5 for the Padres, with a total of 8.5 runs for the game. The odds for the total indicated a slight lean towards the under, with over odds at -105 and under odds at -114.
The game conditions were typical for San Diego, with clear skies and a slight breeze, providing an excellent backdrop for a night of baseball. Fans were treated to a thrilling contest that showcased both teams' strengths and weaknesses.
The scoring plays highlighted the tension throughout the game. In the fourth inning, Walker hit a home run to left field, scoring Burleson and putting the Cardinals ahead 2-0. The Padres fought back in the ninth inning when Castellanos homered to left-center, bringing Bogaerts home and tying the game at 2-2. The decisive moment came in the tenth inning when Machado hit a sacrifice fly to right field, allowing Laureano to score and sealing the victory for the Padres at 3-2.
This game exemplified the competitive spirit of both teams and set the stage for what promises to be an exciting continuation of this series.
Odds
| Book | Spread | Total | Moneyline |
|---|---|---|---|
| DraftKings | SD -137 | 8.5 o -105 / u -114 | St. Louis Cardinals +114 · San Diego Padres -137 |
Injury report
- Jason Adam60-Day-ILShoulderSan Diego Padres
- Miguel Andujar10-Day-ILWristSan Diego Padres
- Gavin Sheets10-Day-ILFootSan Diego Padres
- Jeremiah Estrada15-Day-ILShoulderSan Diego Padres
- Lucas Giolito60-Day-ILElbowSan Diego Padres
- Everson Pereira10-Day-ILHandSt. Louis Cardinals
- Ramon UriasDay-To-DayArmSt. Louis Cardinals
- Masyn Winn10-Day-ILThumbSt. Louis Cardinals
- Andre Pallante15-Day-ILElbowSt. Louis Cardinals
- JJ Wetherholt10-Day-ILWristSt. Louis Cardinals
Recent form
San Diego Padres
Last 10: 3-7Streak L24 scored · 5.9 allowed per game1-5 at home
- L0-6vs St. Louis CardinalsMay 9
- L1-2vs St. Louis CardinalsMay 8
- W10-5at San Francisco GiantsMay 6
- L2-3at San Francisco GiantsMay 5
- L0-4vs Chicago White SoxMay 3
- L2-8vs Chicago White SoxMay 2
- L3-8vs Chicago CubsApr 29
- W9-7vs Chicago CubsApr 28
- L7-12at Arizona DiamondbacksApr 26
- W6-4at Arizona DiamondbacksApr 25
St. Louis Cardinals
Last 10: 7-2-1Streak W25 scored · 3.2 allowed per game5-0 away
- W6-0at San Diego PadresMay 9
- W2-1at San Diego PadresMay 8
- L2-6vs Milwaukee BrewersMay 6
- D0-0vs Milwaukee BrewersMay 5
- W6-3vs Milwaukee BrewersMay 4
- L1-4vs Los Angeles DodgersMay 3
- W7-2vs Los Angeles DodgersMay 2
- W10-5at Pittsburgh PiratesApr 30
- W5-4at Pittsburgh PiratesApr 29
- W11-7at Pittsburgh PiratesApr 28
Standings
| Team | Games behind | Lost | Streak | Win % | Won |
|---|---|---|---|---|---|
| Milwaukee | - | 53 | W2 | .621 | 87 |
| Chicago | 9 | 62 | L2 | .557 | 78 |
| St. Louis | 17 | 70 | W2 | .500 | 70 |
| Pittsburgh | 19 | 72 | L1 | .486 | 68 |
| Cincinnati | 20 | 73 | W2 | .479 | 67 |
| Los Angeles | - | 57 | L2 | .590 | 82 |
| Arizona | 9 | 67 | W1 | .525 | 74 |
| San Diego | 9.5 | 67 | L2 | .521 | 73 |
| San Francisco | 24.5 | 82 | W1 | .414 | 58 |
| Colorado | 28.5 | 86 | W2 | .386 | 54 |
How the scoring went
- 4th Inning2-0Walker homered to left (425 feet), Burleson scored.
- 9th Inning2-2Castellanos homered to left center (389 feet), Bogaerts scored.
- 10th Inning2-3Machado hit sacrifice fly to right, Laureano scored.
Win probability
Above the line favours San Diego Padres, below favours St. Louis Cardinals.
Venue
- Petco ParkSan Diego, California
- Attendance39795
- OfficialsAndy Fletcher, Alex Tosi, Cory Blaser, Jansen Visconti
Elsewhere
Picks for MLB
MLB rules and settlement
These two, other days
- Padres Triumph Over Cardinals in Final Game of SeriesJun 17, 2026
- Cardinals Edge Padres in Close Contest at Busch StadiumJun 16, 2026
- Cardinals Secure Series Victory Over PadresJun 15, 2026
- Padres Defeat Cardinals 4-2 at Petco ParkMay 9, 2026
- Cardinals Dominate Padres in 6-0 VictoryMay 8, 2026