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MLB · Final

Nationals Defeat Cardinals 6-2 in Season Opener

Saturday, February 21, 2026, 1:05 PM ET · Roger Dean Chevrolet Stadium

Washington Nationals 6, St. Louis Cardinals 2, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Washington Nationals vs St. Louis Cardinals?

Washington Nationals beat St. Louis Cardinals 6-2 at Roger Dean Chevrolet Stadium on February 21, 2026.

The Washington Nationals secured a decisive 6-2 victory over the St. Louis Cardinals at Roger Dean Chevrolet Stadium, marking their second consecutive win of the season and extending their lead in the series to 1-0. This match was particularly notable as it showcased the Nationals' ability to capitalize on their offensive opportunities, while the Cardinals struggled to maintain momentum after a recent downturn in form.

In terms of recent performance, the Cardinals entered the game with a home record of 0-1 and a troubling four-game losing streak, having averaged 3.9 runs scored and 4.6 runs allowed over their last ten games. Their last five games saw them average just 3.2 runs while allowing 6.6, indicating significant defensive issues. In contrast, the Nationals had a better away record of 2-0, with an average of 4.4 runs scored and 6.6 runs allowed over their last ten games, despite a recent loss that snapped a brief winning streak.

The game began with the Cardinals taking an early lead in the second inning when Church homered to right, putting them up 1-0. However, the Nationals quickly responded in the third inning with Lipscomb's single, allowing Petersen to score and leveling the game at 1-1. The fourth inning saw a flurry of scoring; Ford's single brought in Rogers for the Nationals, giving them a 2-1 lead, but a wild pitch by Yean allowed Wetherholt to score, tying the game again at 2-2.

The Nationals regained control in the fifth inning. Alcántara's single brought Mervis home, and shortly after, Romero Jr. hit a significant home run, scoring Glasser and Alcántara, which solidified their lead at 6-2. The Cardinals were unable to respond effectively, and the game concluded with the Nationals firmly in control.

In terms of injuries, the Cardinals were notably affected, with several key players sidelined. Everson Pereira and Masyn Winn were both on the 10-Day Injured List, while Ramon Urias was listed as Day-To-Day with an arm issue. The Nationals also faced injury challenges, with Keibert Ruiz listed as Day-To-Day due to a head injury, and Richard Lovelady on the 60-Day Injured List for triceps issues.

The betting market reflected the competitive nature of the matchup, with the Cardinals having a home win probability of 0.0 at the conclusion of the game, indicating a lack of confidence in their ability to secure a victory. The conditions at Roger Dean Chevrolet Stadium were typical for a February evening, providing a solid backdrop for the season opener.

Overall, this game highlighted the Nationals' offensive strength and the Cardinals' ongoing struggles, setting the stage for an intriguing series ahead. Fans should watch for how the Cardinals respond in their next game, particularly in addressing their recent scoring difficulties and defensive lapses.

Injury report

  • Everson Pereira10-Day-ILHandSt. Louis Cardinals
  • Ramon UriasDay-To-DayArmSt. Louis Cardinals
  • Masyn Winn10-Day-ILThumbSt. Louis Cardinals
  • Andre Pallante15-Day-ILElbowSt. Louis Cardinals
  • JJ Wetherholt10-Day-ILWristSt. Louis Cardinals
  • Keibert RuizDay-To-DayHeadWashington Nationals
  • Richard Lovelady60-Day-ILTricepsWashington Nationals
  • Cade CavalliDay-To-DayLower LegWashington Nationals
  • Josiah Gray60-Day-ILElbowWashington Nationals
  • DJ Herz60-Day-ILElbowWashington Nationals

Recent form

St. Louis Cardinals

Last 10: 5-5Streak L43.9 scored · 4.6 allowed per game3-1 at home

  • L0-2at Chicago CubsSep 28
  • L3-7at Chicago CubsSep 27
  • L1-12at Chicago CubsSep 26
  • L3-4at San Francisco GiantsSep 25
  • W9-8at San Francisco GiantsSep 24
  • W6-5at San Francisco GiantsSep 23
  • W5-1vs Milwaukee BrewersSep 21
  • W7-1vs Milwaukee BrewersSep 20
  • L2-6vs Cincinnati RedsSep 17
  • W3-0vs Cincinnati RedsSep 16

Washington Nationals

Last 10: 4-6Streak L14.4 scored · 6.6 allowed per game3-3 away

  • L0-8vs Chicago White SoxSep 28
  • W6-5vs Chicago White SoxSep 27
  • L9-10vs Chicago White SoxSep 26
  • W4-3at Atlanta BravesSep 24
  • L2-3at Atlanta BravesSep 23
  • L5-11at Atlanta BravesSep 22
  • W3-2at New York MetsSep 21
  • W5-3at New York MetsSep 20
  • L6-12at New York MetsSep 19
  • L4-9vs Atlanta BravesSep 17

Standings

TeamGames behindLostStreakWin %Won
Atlanta-57W1.59383
Philadelphia461L1.56479
Miami1269W2.50771
Washington1775L1.47267
New York2077W1.45063
Milwaukee-53W2.62187
Chicago962L2.55778
St. Louis1770W2.50070
Pittsburgh1972L1.48668
Cincinnati2073W2.47967

How the scoring went

  1. 2nd Inning0-1Church homered to right (374 feet).
  2. 3rd Inning1-1Lipscomb singled to left, Petersen scored, Ford to third.
  3. 4th Inning2-1Ford singled to right, Rogers scored, Petersen to third.
  4. 4th Inning2-2Wetherholt scored on Yean wild pitch, Fermín to third on wild pitch by Yean.
  5. 4th Inning2-2Wetherholt scored on Yean wild pitch, Fermín to third.
  6. 5th Inning3-2Alcántara singled to left, Mervis scored, Glasser to second.
  7. 5th Inning6-2Romero Jr. homered to right (402 feet), Glasser scored and Alcántara scored.

Win probability

Above the line favours St. Louis Cardinals, below favours Washington Nationals.

Venue

  • Roger Dean Chevrolet StadiumJupiter, Florida
  • Attendance4267
  • OfficialsJames Jean, Ramon De Jesus, Ron Kulpa, Edwin Moscoso

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.