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MLB · Final

Diamondbacks Outlast White Sox in High-Scoring Affair

Wednesday, April 22, 2026, 9:40 PM ET · Chase Field

Arizona Diamondbacks 11, Chicago White Sox 7, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Chicago White Sox vs Arizona Diamondbacks?

Arizona Diamondbacks beat Chicago White Sox 11-7 at Chase Field on April 22, 2026.

Who was favored in Chicago White Sox vs Arizona Diamondbacks?

Arizona Diamondbacks were the favorite at DraftKings, moneyline -149 (about 60% implied). The favorite won.

The Arizona Diamondbacks triumphed over the Chicago White Sox with a final score of 11-7 at Chase Field, marking an exciting conclusion to their three-game series, which the White Sox won 2-1. This game showcased a high-scoring affair, with both teams combining for 18 runs, a testament to their offensive capabilities.

The Diamondbacks entered the game with a home record of 14-10 and had been performing well recently, boasting a record of 7-3 in their last ten games, although they were on a one-game losing streak. They averaged 5.5 runs scored and allowed 4.5 runs per game during that stretch. Their last game before this one was a loss to the White Sox, where they fell 5-11. In contrast, the White Sox, with a record of 9-15, were 5-5 in their last ten games and riding a three-game winning streak. They averaged 4.6 runs scored and allowed 4.1 runs per game over their last ten games.

At home, the Diamondbacks had a record of 2-1 in their last three games, while the White Sox struggled on the road, holding a 0-3 record in their last three away games. The matchup was particularly noteworthy as it was the second meeting of the series, following the White Sox's victory the previous day.

In terms of head-to-head matchups, the Diamondbacks and White Sox have faced each other four times in the past two seasons, with a balanced record of 2-2. The most recent encounter before this game was on April 22, 2026, where the Diamondbacks lost to the White Sox 5-11.

Injuries played a significant role in this matchup. The Diamondbacks were missing several key players, including Tommy Troy (10-Day IL, shoulder), Ryne Nelson (60-Day IL, elbow), Zac Gallen (60-Day IL, elbow), Michael Soroka (15-Day IL, shoulder), and Corbin Burnes (60-Day IL, elbow). The White Sox also had their share of injuries, with Chris Murphy (15-Day IL, forearm), Kyle Teel (10-Day IL, ankle), Tanner Murray (60-Day IL, shoulder), Drew Thorpe (60-Day IL, elbow), and Huascar Brazoban (15-Day IL, lat) unavailable for the game.

The betting market, as reported by DraftKings, opened with the Diamondbacks favored at -149 on the money line, with a spread of -1.5 and a total set at 9.0 runs. The over odds were at -108.0, while the under odds were at -112.0, indicating a competitive expectation for the game's scoring.

As for the conditions during the game, it was played at Chase Field, known for its favorable hitting environment, which likely contributed to the offensive outburst. Fans were treated to several exciting moments, including a notable homer by Montgomery in the fourth inning, which was a highlight of the game.

The scoring plays were dynamic, with the Diamondbacks taking control early and maintaining their lead throughout. In the fourth inning, Montgomery homered to right center, followed by a series of runs that included Carroll scoring on a balk and Arenado's single that brought in Perdomo. The Diamondbacks capitalized on their opportunities, with a significant triple from Perdomo in the seventh inning that allowed Carroll to score, solidifying their lead.

Overall, this game was a thrilling showcase of baseball, with both teams demonstrating their offensive prowess amid the backdrop of injuries and competitive stakes. The Diamondbacks' victory not only avenged their previous loss but also highlighted their ability to bounce back in a high-pressure situation.

Odds

BookSpreadTotalMoneyline
DraftKingsARI -149 9 o -108 / u -112 Chicago White Sox +123 · Arizona Diamondbacks -149

What these prices pay on $100 · What these numbers mean

Injury report

  • Tommy Troy10-Day-ILShoulderArizona Diamondbacks
  • Ryne Nelson60-Day-ILElbowArizona Diamondbacks
  • Zac Gallen60-Day-ILElbowArizona Diamondbacks
  • Michael Soroka15-Day-ILShoulderArizona Diamondbacks
  • Corbin Burnes60-Day-ILElbowArizona Diamondbacks
  • Chris Murphy15-Day-ILForearmChicago White Sox
  • Kyle Teel10-Day-ILAnkleChicago White Sox
  • Tanner Murray60-Day-ILShoulderChicago White Sox
  • Drew Thorpe60-Day-ILElbowChicago White Sox
  • Huascar Brazoban15-Day-ILLatChicago White Sox

Recent form

Arizona Diamondbacks

Last 10: 7-3Streak L15.5 scored · 4.5 allowed per game2-1 at home

  • L5-11vs Chicago White SoxApr 22
  • W6-2vs Toronto Blue JaysApr 19
  • W6-3vs Toronto Blue JaysApr 18
  • W8-5at Baltimore OriolesApr 15
  • W4-3at Baltimore OriolesApr 14
  • L7-9at Baltimore OriolesApr 13
  • W4-3at Philadelphia PhilliesApr 12
  • L3-4at Philadelphia PhilliesApr 11
  • W5-4at Philadelphia PhilliesApr 10
  • W7-1at New York MetsApr 9

Chicago White Sox

Last 10: 5-5Streak W34.6 scored · 4.1 allowed per game5-2 away

  • W11-5at Arizona DiamondbacksApr 22
  • W7-4at AthleticsApr 19
  • W9-2at AthleticsApr 18
  • L3-5vs Tampa Bay RaysApr 16
  • L3-8vs Tampa Bay RaysApr 15
  • L5-8vs Tampa Bay RaysApr 14
  • W6-5at Kansas City RoyalsApr 12
  • L0-2at Kansas City RoyalsApr 11
  • L0-2at Kansas City RoyalsApr 10
  • W2-0at Kansas City RoyalsApr 9

Standings

TeamGames behindLostStreakWin %Won
Chicago-66L1.52573
Cleveland369L1.50470
Minnesota6.573L1.47967
Detroit975W1.46064
Kansas City11.578L3.44362
Los Angeles-57L2.59082
Arizona967W1.52574
San Diego9.567L2.52173
San Francisco24.582W1.41458
Colorado28.586W2.38654

How the scoring went

  1. 1st Inning1-0Quero walked, Meidroth scored, Pereira to second, Vargas to third.
  2. 1st Inning2-0Montgomery grounded into fielder's choice to second, Vargas scored, Quero out at second, Pereira to third.
  3. 2nd Inning2-3Vargas homered to left (420 feet), Fernandez scored and Arenado scored.
  4. 2nd Inning2-4Carroll singled to right, Marte scored.
  5. 3rd Inning3-4Vargas homered to left center (428 feet).
  6. 3rd Inning3-6Vargas homered to left center (405 feet), Arenado scored.
  7. 4th Inning4-6Montgomery homered to right center (423 feet).
  8. 4th Inning4-7Carroll scored on a balk, Perdomo to second on a balk.
  9. 4th Inning4-7Carroll scored on a balk, Perdomo to second on a balk.
  10. 4th Inning4-8Arenado singled to center, Perdomo scored, Fernandez to third.
  11. 6th Inning5-8Benintendi grounded out to second, Peters scored.
  12. 6th Inning5-10Arenado homered to left center (411 feet), Fernandez scored.
  13. 7th Inning7-10Murakami homered to center (451 feet), Vargas scored.
  14. 7th Inning7-11Perdomo tripled to left, Carroll scored.

Win probability

Above the line favours Arizona Diamondbacks, below favours Chicago White Sox.

Venue

  • Chase FieldPhoenix, Arizona
  • Attendance20799
  • OfficialsJeremie Rehak, Cory Blaser, Adam Beck, Doug Eddings

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.