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MLB · Final/10

Cardinals Edge Guardians in Extra Innings Thriller

Tuesday, April 14, 2026, 7:45 PM ET · Busch Stadium

St. Louis Cardinals 6, Cleveland Guardians 5, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Cleveland Guardians vs St. Louis Cardinals?

St. Louis Cardinals beat Cleveland Guardians 6-5 at Busch Stadium on April 14, 2026.

Who was favored in Cleveland Guardians vs St. Louis Cardinals?

Cleveland Guardians were the favorite at DraftKings, moneyline -131 (about 57% implied). The underdog won.

In a dramatic finish, the St. Louis Cardinals triumphed over the Cleveland Guardians with a score of 6-5 after ten innings at Busch Stadium. This victory allowed the Cardinals to win the series 2-1 against the Guardians. The game showcased a back-and-forth battle, highlighted by key home runs and clutch hits that kept fans on the edge of their seats.

Both teams entered the game with slightly different recent forms. The Cardinals had a record of 5-5 in their last ten games, but they were on a two-game losing streak, having lost their previous two games against the Guardians and the Boston Red Sox. Their average runs scored during this stretch was 4.1, while they allowed an average of 5.5 runs per game. In contrast, the Guardians had a record of 5-4-1 in their last ten games, with a recent win against the Cardinals after a tough loss to the Atlanta Braves. The Guardians averaged 3.9 runs scored and allowed 3.6 runs during this period.

When looking at their home and away performances, the Cardinals had a home record of 2-2 in their last four games at Busch Stadium, while their away record stood at 3-3. The Guardians, on the other hand, had a home record of 3-2 and an away record of 2-2 in their recent games, indicating a balanced performance regardless of location.

In terms of head-to-head matchups, the Cardinals had won three out of their last four encounters with the Guardians, including a decisive 7-0 victory in June 2025. However, the Guardians had recently bested the Cardinals 9-3 just a day prior to this game, indicating that the series was highly competitive.

Injuries played a significant role in the game, particularly for the Cardinals, who were missing several key players. Masyn Winn, Everson Pereira, Andre Pallante, JJ Wetherholt, and Peter Strzelecki were all on the injured list, impacting the team's depth. The Guardians were also dealing with injuries, including Slade Cecconi, Rhys Hoskins, and Shawn Armstrong, which affected their lineup as well.

The betting market reflected the competitive nature of the matchup, with DraftKings listing the Guardians as the favorites at -131, while the Cardinals were priced at +109 for the money line. The spread was set at 1.5, and the total runs were pegged at 9.0, with odds for the over at -108 and the under at -112.

The game conditions were favorable for baseball, with clear skies and a temperature that allowed players to perform at their best. Fans were treated to a showcase of power hitting, as both teams connected for home runs. Notably, Wetherholt hit two home runs during the game, contributing significantly to the Cardinals’ scoring efforts.

The scoring plays were pivotal in shaping the game's outcome. The Cardinals initially fell behind when Schneemann homered in the second inning, but they quickly responded with Wetherholt's home run in the third. The Guardians extended their lead in the eighth inning with a double from Valera, followed by a critical two-run double from Martínez, putting them ahead 5-2. However, the Cardinals rallied back in the ninth inning, tying the game at 5-5 thanks to a double from Pozo that brought in Winn.

Ultimately, the decisive moment came in the tenth inning when Church hit a sacrifice fly that allowed Saggese to score, sealing the victory for the Cardinals. This game not only showcased the resilience of the Cardinals but also highlighted the competitive spirit of the Guardians, making it a thrilling encounter for fans of both teams.

Odds

BookSpreadTotalMoneyline
DraftKingsCLE -131 9 o -108 / u -112 Cleveland Guardians -131 · St. Louis Cardinals +109

What these prices pay on $100 · What these numbers mean

Injury report

  • Masyn Winn10-Day-ILThumbSt. Louis Cardinals
  • Everson Pereira10-Day-ILHandSt. Louis Cardinals
  • Andre Pallante15-Day-ILElbowSt. Louis Cardinals
  • JJ Wetherholt10-Day-ILWristSt. Louis Cardinals
  • Peter Strzelecki15-Day-ILForearmSt. Louis Cardinals
  • Slade Cecconi15-Day-ILArmCleveland Guardians
  • Rhys Hoskins10-Day-ILBackCleveland Guardians
  • Shawn Armstrong60-Day-ILCalfCleveland Guardians

Recent form

St. Louis Cardinals

Last 10: 5-5Streak L24.1 scored · 5.5 allowed per game2-2 at home

  • L3-9vs Cleveland GuardiansApr 13
  • L3-9vs Boston Red SoxApr 12
  • W3-2vs Boston Red SoxApr 11
  • W6-1at Washington NationalsApr 8
  • W7-6at Washington NationalsApr 7
  • L6-9at Washington NationalsApr 6
  • W5-3at Detroit TigersApr 5
  • L6-11at Detroit TigersApr 4
  • L0-4at Detroit TigersApr 3
  • W2-1vs New York MetsApr 1

Cleveland Guardians

Last 10: 5-4-1Streak W13.9 scored · 3.6 allowed per game2-2 away

  • W9-3at St. Louis CardinalsApr 13
  • L1-13at Atlanta BravesApr 12
  • W6-0at Atlanta BravesApr 11
  • L5-11at Atlanta BravesApr 10
  • W10-2vs Kansas City RoyalsApr 8
  • W2-1vs Kansas City RoyalsApr 7
  • L2-4vs Kansas City RoyalsApr 6
  • L0-1vs Chicago CubsApr 5
  • D0-0vs Chicago CubsApr 4
  • W4-1vs Chicago CubsApr 3

Standings

TeamGames behindLostStreakWin %Won
Chicago-66L1.52573
Cleveland369L1.50470
Minnesota6.573L1.47967
Detroit975W1.46064
Kansas City11.578L3.44362
Milwaukee-53W2.62187
Chicago962L2.55778
St. Louis1770W2.50070
Pittsburgh1972L1.48668
Cincinnati2073W2.47967

How the scoring went

  1. 1st Inning1-0Ramírez homered to right (398 feet).
  2. 1st Inning1-1Herrera homered to left (401 feet).
  3. 2nd Inning2-1Schneemann homered to center (424 feet).
  4. 3rd Inning2-2Wetherholt homered to right center (396 feet).
  5. 8th Inning3-2Valera doubled to left, Ramírez scored, Manzardo to third.
  6. 8th Inning5-2Martínez doubled to right, Brito scored and Manzardo scored.
  7. 8th Inning5-4Wetherholt homered to left (366 feet), Fermín scored.
  8. 9th Inning5-5Pozo doubled to right, Winn scored.
  9. 10th Inning5-6Church hit sacrifice fly to right, Saggese scored.

Win probability

Above the line favours St. Louis Cardinals, below favours Cleveland Guardians.

Venue

  • Busch StadiumSt. Louis, Missouri
  • Attendance20772
  • OfficialsRoberto Ortiz, Alex Mackay, Alan Porter, Jim Wolf

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.