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MLB · Final

White Sox Dominate Astros in Series Finale

Sunday, July 26, 2026, 2:10 PM ET · Rate Field

Chicago White Sox 12, Houston Astros 3, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Houston Astros vs Chicago White Sox?

Chicago White Sox beat Houston Astros 12-3 at Rate Field on July 26, 2026.

Who was favored in Houston Astros vs Chicago White Sox?

Chicago White Sox were the favorite at DraftKings, moneyline -123 (about 55% implied). The favorite won.

In a decisive victory, the Chicago White Sox defeated the Houston Astros 12-3 at Rate Field, concluding the series with the Astros winning 2-1. This match showcased the White Sox’s offensive prowess, particularly in the latter innings, where they scored a significant portion of their runs. The White Sox, now holding a record of 55-49, have demonstrated a solid home performance this season, although they recently faced challenges, losing their last two games against the Astros prior to this matchup.

The White Sox entered this game with a 6-4 record over their last ten games, but were on a two-game losing streak. They had averaged 4.5 runs scored per game while allowing 3.4 runs. Their recent form included losses against the Astros in the two previous games of the series, with scores of 1-4 and 5-9. At home, their record stands at 2-2 in their last four games, while they have fared better away with a 4-2 record.

The Astros, on the other hand, came into this game with a 52-55 record and a 5-5 record over their last ten games, riding a five-game winning streak prior to this loss. They had also averaged 4.5 runs scored per game, but matched that with an equal average of 4.5 runs allowed. Their recent victories included two wins against the Miami Marlins before facing the White Sox, where they had previously secured wins of 4-1 and 9-5.

In terms of head-to-head matchups, the Astros have had the upper hand recently, winning five of the last eight encounters against the White Sox. The most recent games prior to this one saw the White Sox struggle, with losses in both games played in this series. The White Sox's last victory against the Astros was on June 11, 2025, where they won 4-2.

Injury concerns for the White Sox included Chris Murphy (forearm), Kyle Teel (ankle), Tanner Murray (shoulder), Drew Thorpe (elbow), and Huascar Brazoban (lat), all of whom were on the injured list. The Astros also faced challenges with injuries, having Brice Matthews (knee), Mike Burrows (elbow), Carlos Correa (ankle), and Brandon Walter (elbow) on the injured list.

The betting odds from DraftKings indicated the White Sox as the favorites at -123, with a spread of 1.5 and a total set at 9.0. The odds for the over were -111.0, while the under was priced at -109. The money line for the White Sox was -123, while the Astros were at +102.

Conditions for the game were typical for a summer evening in Chicago, providing a favorable environment for baseball. The White Sox capitalized on this, with notable scoring plays throughout the game. Key moments included a homer from Vargas in the sixth inning, which put the White Sox ahead 5-3, and a series of runs in the seventh inning that extended their lead significantly. The scoring continued into the eighth inning with homers from Perez and Murakami, culminating in a dominant 12-run performance.

Viewers should have noted the offensive strategy employed by the White Sox, particularly their ability to capitalize on mistakes and leverage their power hitting in crucial moments. The White Sox's ability to score in bursts, especially late in the game, was a significant factor in their victory. This game not only highlighted the White Sox's strengths but also showcased the Astros' vulnerabilities, particularly in their pitching during the latter innings.

Odds

BookSpreadTotalMoneyline
DraftKingsCHW -123 9 o -111 / u -109 Houston Astros +102 · Chicago White Sox -123

What these prices pay on $100 · What these numbers mean

Injury report

  • Chris Murphy15-Day-ILForearmChicago White Sox
  • Kyle Teel10-Day-ILAnkleChicago White Sox
  • Tanner Murray60-Day-ILShoulderChicago White Sox
  • Drew Thorpe60-Day-ILElbowChicago White Sox
  • Huascar Brazoban15-Day-ILLatChicago White Sox
  • Brice Matthews60-Day-ILKneeHouston Astros
  • Mike Burrows15-Day-ILElbowHouston Astros
  • Carlos Correa60-Day-ILAnkleHouston Astros
  • Brandon Walter60-Day-ILElbowHouston Astros

Recent form

Chicago White Sox

Last 10: 6-4Streak L24.5 scored · 3.4 allowed per game2-2 at home

  • L1-4vs Houston AstrosJul 25
  • L5-9vs Houston AstrosJul 24
  • W4-2at Texas RangersJul 23
  • L0-10at Texas RangersJul 22
  • W10-3at Texas RangersJul 21
  • W3-0at Toronto Blue JaysJul 19
  • L0-1at Toronto Blue JaysJul 18
  • W12-4at Toronto Blue JaysJul 17
  • W9-1vs AthleticsJul 12
  • W1-0vs AthleticsJul 11

Houston Astros

Last 10: 5-5Streak W54.5 scored · 4.5 allowed per game2-3 away

  • W4-1at Chicago White SoxJul 25
  • W9-5at Chicago White SoxJul 24
  • W5-2vs Miami MarlinsJul 23
  • W5-3vs Miami MarlinsJul 22
  • W8-5vs Miami MarlinsJul 21
  • L2-5vs Baltimore OriolesJul 19
  • L2-3vs Baltimore OriolesJul 18
  • L5-6at Texas RangersJul 12
  • L3-7at Texas RangersJul 11
  • L2-8at Washington NationalsJul 8

Standings

TeamGames behindLostStreakWin %Won
Houston-69W1.50771
Texas271L1.49369
Seattle574W2.47166
Athletics1786W1.38654
Los Angeles1887L2.37953
Chicago-66L1.52573
Cleveland369L1.50470
Minnesota6.573L1.47967
Detroit975W1.46064
Kansas City11.578L3.44362

How the scoring went

  1. 1st Inning1-0Peña homered to left (393 feet).
  2. 1st Inning1-2Murakami homered to left (385 feet), Antonacci scored.
  3. 3rd Inning2-2Peña homered to right center (394 feet).
  4. 3rd Inning2-3Murakami grounded out to second, Romo scored, Antonacci to third.
  5. 5th Inning3-3Trammell homered to center (426 feet).
  6. 6th Inning3-5Vargas homered to left (393 feet), Antonacci scored.
  7. 7th Inning3-6Meidroth homered to left center (382 feet).
  8. 7th Inning3-8Murakami singled to center, Romo scored and Perez scored.
  9. 7th Inning3-9Benintendi singled to left, Murakami scored, B. Montgomery to second.
  10. 8th Inning3-11Perez homered to left (376 feet), Meidroth scored.
  11. 8th Inning3-12Murakami homered to right center (398 feet).

Win probability

Above the line favours Chicago White Sox, below favours Houston Astros.

Venue

  • Rate FieldChicago, Illinois
  • Attendance32581
  • OfficialsMark Ripperger, Dan Bellino, Dexter Kelley, Shane Livensparger

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.