Cardinals Edge Astros in Close Contest
Sunday, February 22, 2026, 1:05 PM ET · CACTI Park of the Palm Beaches
St. Louis Cardinals 6, Houston Astros 5, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.
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Quick answers
Who won St. Louis Cardinals vs Houston Astros?
St. Louis Cardinals beat Houston Astros 6-5 at CACTI Park of the Palm Beaches on February 22, 2026.
In a tightly contested game at CACTI Park of the Palm Beaches, the St. Louis Cardinals triumphed over the Houston Astros with a final score of 6-5. This victory extends the Cardinals' lead in the series to 2-0, having previously won their first meeting in April 2025. The game showcased a blend of solid offensive plays and critical moments that ultimately determined the outcome.
The Astros entered this matchup with a home record of 0-2 in the current series and a recent form of 4-6 over their last ten games, including a streak of one win. They averaged 3.3 runs scored per game while allowing 4.5 runs. In their last five games, their scoring average dipped to 2.6 runs, indicating struggles at the plate. The Astros' recent performances included a win against the Los Angeles Angels, but they faced multiple losses against teams like the Athletics and the Seattle Mariners.
On the other hand, the Cardinals had a record of 1-1 in the series and were 5-5 over their last ten games, though they were currently on a four-game losing streak. Their scoring average stood at 3.9 runs per game, with an average of 4.6 runs allowed. The Cardinals' recent form included a notable win against the San Francisco Giants, but they also suffered defeats against the Chicago Cubs, highlighting their inconsistency.
In terms of home and away performance, the Astros had a home record of 3-2 and an away record of 1-4, while the Cardinals boasted a home record of 3-1 and an away record of 2-4. This disparity in performance could have played a role in the game’s dynamics.
Injuries were a significant factor for both teams. The Astros were missing key players, including Brice Matthews and Carlos Correa, both on the 60-day injured list, along with Mike Burrows and Brandon Walter, who were also sidelined. The Cardinals faced their own challenges with Everson Pereira on the 10-day injured list and Ramon Urias listed as day-to-day. Masyn Winn, Andre Pallante, and JJ Wetherholt were also unavailable, impacting the Cardinals' depth.
The game itself featured several pivotal moments. The Cardinals took an early lead in the third inning with a series of scoring plays, including a double by Pozo that brought in two runs. They extended their lead further in the fifth inning, capitalizing on defensive errors by the Astros. The Astros managed to rally in the later innings, scoring three runs in the ninth, but ultimately fell short.
Betting lines from the market indicated a low probability for the Astros to win, with a final home win probability of 0.0, suggesting that the Cardinals were favored in this matchup.
Conditions during the game were typical for the venue, contributing to the overall competitive atmosphere. Viewers could watch for the Astros' struggle to capitalize on scoring opportunities and the Cardinals' ability to maintain their lead despite late-game pressure.
Overall, this game highlighted the challenges both teams face as they navigate through the season, with the Cardinals emerging victorious and gaining momentum in the series.
Injury report
- Brice Matthews60-Day-ILKneeHouston Astros
- Mike Burrows15-Day-ILElbowHouston Astros
- Carlos Correa60-Day-ILAnkleHouston Astros
- Brandon Walter60-Day-ILElbowHouston Astros
- Everson Pereira10-Day-ILHandSt. Louis Cardinals
- Ramon UriasDay-To-DayArmSt. Louis Cardinals
- Masyn Winn10-Day-ILThumbSt. Louis Cardinals
- Andre Pallante15-Day-ILElbowSt. Louis Cardinals
- JJ Wetherholt10-Day-ILWristSt. Louis Cardinals
Recent form
Houston Astros
Last 10: 4-6Streak W13.3 scored · 4.5 allowed per game3-2 at home
- W6-1at Los Angeles AngelsSep 28
- L3-4at Los Angeles AngelsSep 27
- L0-6at AthleticsSep 25
- L1-5at AthleticsSep 24
- L3-7vs Seattle MarinersSep 21
- L0-4vs Seattle MarinersSep 20
- W5-2vs Texas RangersSep 18
- W6-5vs Texas RangersSep 17
- W6-3vs Texas RangersSep 16
- L3-8at Atlanta BravesSep 14
St. Louis Cardinals
Last 10: 5-5Streak L43.9 scored · 4.6 allowed per game2-4 away
- L0-2at Chicago CubsSep 28
- L3-7at Chicago CubsSep 27
- L1-12at Chicago CubsSep 26
- L3-4at San Francisco GiantsSep 25
- W9-8at San Francisco GiantsSep 24
- W6-5at San Francisco GiantsSep 23
- W5-1vs Milwaukee BrewersSep 21
- W7-1vs Milwaukee BrewersSep 20
- L2-6vs Cincinnati RedsSep 17
- W3-0vs Cincinnati RedsSep 16
Standings
| Team | Games behind | Lost | Streak | Win % | Won |
|---|---|---|---|---|---|
| Milwaukee | - | 53 | W2 | .621 | 87 |
| Chicago | 9 | 62 | L2 | .557 | 78 |
| St. Louis | 17 | 70 | W2 | .500 | 70 |
| Pittsburgh | 19 | 72 | L1 | .486 | 68 |
| Cincinnati | 20 | 73 | W2 | .479 | 67 |
| Houston | - | 69 | W1 | .507 | 71 |
| Texas | 2 | 71 | L1 | .493 | 69 |
| Seattle | 5 | 74 | W2 | .471 | 66 |
| Athletics | 17 | 86 | W1 | .386 | 54 |
| Los Angeles | 18 | 87 | L2 | .379 | 53 |
How the scoring went
- 2nd Inning0-1Winkler homered to left (397 feet).
- 3rd Inning1-1Saggese singled to center, Rodriguez scored.
- 3rd Inning3-1Pozo doubled to left, Saggese scored and Walker scored, Velázquez to third.
- 3rd Inning4-1Prieto grounded out to first, Velázquez scored, Pozo to third.
- 5th Inning5-1Prieto grounded out to second, Walker scored, Petrutz to second, Velázquez to third.
- 5th Inning6-1Velázquez scored, Rodriguez safe at first on fielding error by first baseman Price, Jordan to second, Petrutz out at home in rundown.
- 6th Inning6-2Meyers singled to right, Janek scored, Trammell to third.
- 9th Inning6-3Garcia hit sacrifice fly to left, Ferreras scored.
- 9th Inning6-4Unroe singled to center, Ramirez scored, Daudet to third.
- 9th Inning6-5Wakefield singled to left, Daudet scored, Unroe to second.
Win probability
Above the line favours Houston Astros, below favours St. Louis Cardinals.
Venue
- CACTI Park of the Palm BeachesPalm Beach, Florida
- Attendance2598
- OfficialsRyan Additon, Ron Kulpa, Carlos Torres, John Bacon
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- Rangers begin 4-game series against the Rays
- Astros face the White Sox leading series 2-1
- Orioles begin 4-game series with the Red Sox
- Guardians and Blue Jays play with series tied 1-1
Picks for MLB
MLB rules and settlement
These two, other days
- Cardinals Edge Astros in Extra Innings ShowdownApr 19, 2026
- Cardinals Complete Sweep Over Astros in Close ContestApr 18, 2026
- Cardinals Sweep Astros in Impressive Series FinaleApr 17, 2026
- Cardinals Edge Astros in Close ContestMar 22, 2026
- Cardinals Defeat Astros 4-1 in MLB ClashMar 18, 2026