Angels Secure Series Win Over Cardinals 5-1
Tuesday, July 21, 2026, 9:38 PM ET · Angel Stadium
Los Angeles Angels 5, St. Louis Cardinals 1, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.
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Quick answers
Who won St. Louis Cardinals vs Los Angeles Angels?
Los Angeles Angels beat St. Louis Cardinals 5-1 at Angel Stadium on July 21, 2026.
Who was favored in St. Louis Cardinals vs Los Angeles Angels?
Los Angeles Angels were the favorite at DraftKings, moneyline -126 (about 56% implied). The favorite won.
In an impressive display, the Los Angeles Angels defeated the St. Louis Cardinals 5-1 at Angel Stadium, clinching the series 2-1. The Angels, with a home record of 41-61, showcased their ability to capitalize on early scoring opportunities, taking a commanding lead in the first inning that they maintained throughout the game.
The Angels' recent form has shown some signs of improvement, with a record of 3-7 over their last ten games. They averaged 3.8 runs scored while allowing 4.9 runs during that stretch. Notably, they had just come off a narrow 3-2 victory against the Cardinals the previous day, which was part of their current streak of one win. In contrast, the Cardinals, with a record of 51-49, have struggled recently, going 4-6 in their last ten games, averaging 3.7 runs scored and 3.7 runs allowed. Their two-game losing streak was extended with this loss to the Angels.
At home, the Angels have recorded a 1-4 record in their last five games, scoring an average of 2.0 runs and allowing 3.6 runs. The Cardinals, meanwhile, have a home record of 2-4 in their last six games, with a more balanced average of 3.8 runs scored and 4.0 runs allowed. The Angels' ability to perform at home against the Cardinals has been evident, as they have won three of their last four meetings.
In terms of injuries, the Angels are dealing with several key players sidelined, including Josh Lowe, who is day-to-day with a neck issue, and Gustavo Campero, Nolan Schanuel, and Sam Bachman, all on the injured list for various ailments. The Cardinals are also facing injury challenges, with Everson Pereira on the 10-day injured list due to a hand issue, while Ramon Urias is day-to-day with an arm injury. Other Cardinals on the injured list include Masyn Winn, Andre Pallante, and JJ Wetherholt.
The betting market, as provided by DraftKings, had the Angels favored at -126 with a spread of -1.5 and a total set at 9.0. The odds for the over were -120, while the under was priced at 100. The Angels' moneyline was -126, indicating a strong belief in their chances to win, especially given their recent performance against the Cardinals.
The weather conditions during the game were conducive to play, allowing both teams to focus on their strategies without external disruptions. Fans watching the game were treated to a showcase of offensive prowess from the Angels, particularly in the first inning. The scoring began with Jorge Soler doubling to left field, bringing in Schanuel and Trout for the first two runs. Grissom followed with a single that allowed Soler to score, making it 3-0. The inning concluded with Adell hitting a home run to left center, scoring Grissom and extending the Angels' lead to 5-0.
The Cardinals managed to get on the board in the fifth inning when Wetherholt grounded into a fielder's choice, allowing Jordan to score. However, the Angels' early dominance proved too much for the Cardinals to overcome, and they secured a definitive win.
Overall, this game highlighted the Angels' ability to capitalize on scoring opportunities and maintain control throughout the matchup, while the Cardinals will need to regroup and address their recent struggles as they continue their season.
Odds
| Book | Spread | Total | Moneyline |
|---|---|---|---|
| DraftKings | LAA -126 | 9 o -120 / u +100 | St. Louis Cardinals +104 · Los Angeles Angels -126 |
Injury report
- Josh LoweDay-To-DayNeckLos Angeles Angels
- Gustavo Campero10-Day-ILHamstringLos Angeles Angels
- Nolan Schanuel10-Day-ILSideLos Angeles Angels
- Sam Bachman15-Day-ILForearmLos Angeles Angels
- Yoan Moncada60-Day-ILKneeLos Angeles Angels
- Everson Pereira10-Day-ILHandSt. Louis Cardinals
- Ramon UriasDay-To-DayArmSt. Louis Cardinals
- Masyn Winn10-Day-ILThumbSt. Louis Cardinals
- Andre Pallante15-Day-ILElbowSt. Louis Cardinals
- JJ Wetherholt10-Day-ILWristSt. Louis Cardinals
Recent form
Los Angeles Angels
Last 10: 3-7Streak W13.8 scored · 4.9 allowed per game1-4 at home
- W3-2vs St. Louis CardinalsJul 21
- L0-7vs Detroit TigersJul 19
- L1-2vs Detroit TigersJul 18
- L2-4at Minnesota TwinsJul 12
- W4-3at Minnesota TwinsJul 11
- L6-7at Texas RangersJul 10
- W13-1at Texas RangersJul 9
- L3-8at Texas RangersJul 8
- L5-7vs Boston Red SoxJul 6
- L1-8vs Boston Red SoxJul 5
St. Louis Cardinals
Last 10: 4-6Streak L23.7 scored · 3.7 allowed per game2-2 away
- L2-3at Los Angeles AngelsJul 21
- L7-8at Arizona DiamondbacksJul 19
- W5-4at Arizona DiamondbacksJul 18
- L3-4vs Atlanta BravesJul 12
- W2-1vs Atlanta BravesJul 11
- L4-8vs Milwaukee BrewersJul 9
- W5-1vs Milwaukee BrewersJul 8
- L3-4vs Milwaukee BrewersJul 7
- L3-4vs Milwaukee BrewersJul 6
- W3-0at Chicago CubsJul 5
Standings
| Team | Games behind | Lost | Streak | Win % | Won |
|---|---|---|---|---|---|
| Milwaukee | - | 53 | W2 | .621 | 87 |
| Chicago | 9 | 62 | L2 | .557 | 78 |
| St. Louis | 17 | 70 | W2 | .500 | 70 |
| Pittsburgh | 19 | 72 | L1 | .486 | 68 |
| Cincinnati | 20 | 73 | W2 | .479 | 67 |
| Houston | - | 69 | W1 | .507 | 71 |
| Texas | 2 | 71 | L1 | .493 | 69 |
| Seattle | 5 | 74 | W2 | .471 | 66 |
| Athletics | 17 | 86 | W1 | .386 | 54 |
| Los Angeles | 18 | 87 | L2 | .379 | 53 |
How the scoring went
- 1st Inning0-2Soler doubled to left, Schanuel and Trout scored.
- 1st Inning0-3Grissom singled to right, Soler scored, Grissom to second.
- 1st Inning0-5Adell homered to left center (405 feet), Grissom scored.
- 5th Inning1-5Wetherholt grounded into fielder's choice to second, Jordan scored, Torres out at second.
Win probability
Above the line favours Los Angeles Angels, below favours St. Louis Cardinals.
Venue
- Angel StadiumAnaheim, California
- Attendance33151
- OfficialsMark Ripperger, Dan Bellino, Dexter Kelley, Shane Livensparger
Elsewhere
Picks for MLB
MLB rules and settlement
These two, other days
- Cardinals Edge Angels in Close ContestJul 22, 2026
- Angels Edge Cardinals in Close Contest at HomeJul 20, 2026