Cardinals Edge Angels in Close Contest
Wednesday, July 22, 2026, 4:07 PM ET · Angel Stadium
St. Louis Cardinals 1, Los Angeles Angels 0, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.
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Quick answers
Who won St. Louis Cardinals vs Los Angeles Angels?
St. Louis Cardinals beat Los Angeles Angels 1-0 at Angel Stadium on July 22, 2026.
Who was favored in St. Louis Cardinals vs Los Angeles Angels?
Los Angeles Angels were the favorite at DraftKings, moneyline -149 (about 60% implied). The underdog won.
In a tightly contested game at Angel Stadium, the St. Louis Cardinals triumphed over the Los Angeles Angels with a final score of 1-0. This victory allowed the Cardinals to win the series 2-1, showcasing their ability to perform under pressure. The game was marked by a pivotal moment in the sixth inning when JJ Wetherholt hit a solo home run to center field, measuring 409 feet, which proved to be the only run of the game.
The Angels entered this matchup with a home record of 41-62 and had recently struggled, winning only 3 of their last 10 games, with an average of 3.8 runs scored and 4.9 runs allowed during that stretch. Their most recent game before this one was a hard-fought 3-2 victory against the Cardinals on July 21, 2026. However, their overall performance at home has been less than stellar, with a record of 1-4 in their last five home games and an average of just 2.0 runs scored in that time.
On the other hand, the Cardinals came into this game with an away record of 52-49 and had a mixed performance, winning 4 of their last 10 games, averaging 3.7 runs scored and 3.7 runs allowed. Their last game resulted in a 2-3 loss to the Angels, but they had shown resilience with a previous win against the Arizona Diamondbacks just prior to that.
In terms of injuries, the Angels faced several challenges, including Josh Lowe, who was listed as day-to-day with a neck issue, and three players on the injured list: Gustavo Campero (hamstring), Nolan Schanuel (side), and Sam Bachman (forearm). The Cardinals also dealt with injuries, with Everson Pereira on the 10-day injured list due to a hand injury, and Ramon Urias listed as day-to-day with an arm issue.
The betting market, as provided by DraftKings, set the odds for this game with the Angels at -149 and the Cardinals at +123. The spread was set at -1.5, with a total of 8.5 runs for the game, indicating expectations for a low-scoring affair, which ultimately came to fruition.
Conditions for the game were typical for a summer evening in Los Angeles, with clear skies and a temperature conducive to baseball, though the focus remained on the pitchers and defensive plays that contributed to the low score.
Viewers were advised to watch for the pitching duels, as both teams showcased strong performances on the mound. The Cardinals' ability to capitalize on a single scoring opportunity ultimately made the difference in this closely contested matchup, reflecting the ongoing competitive nature of both teams in the league.
Odds
| Book | Spread | Total | Moneyline |
|---|---|---|---|
| DraftKings | LAA -149 | 8.5 o -119 / u -101 | St. Louis Cardinals +123 · Los Angeles Angels -149 |
Injury report
- Josh LoweDay-To-DayNeckLos Angeles Angels
- Gustavo Campero10-Day-ILHamstringLos Angeles Angels
- Nolan Schanuel10-Day-ILSideLos Angeles Angels
- Sam Bachman15-Day-ILForearmLos Angeles Angels
- Yoan Moncada60-Day-ILKneeLos Angeles Angels
- Everson Pereira10-Day-ILHandSt. Louis Cardinals
- Ramon UriasDay-To-DayArmSt. Louis Cardinals
- Masyn Winn10-Day-ILThumbSt. Louis Cardinals
- Andre Pallante15-Day-ILElbowSt. Louis Cardinals
- JJ Wetherholt10-Day-ILWristSt. Louis Cardinals
Recent form
Los Angeles Angels
Last 10: 3-7Streak W13.8 scored · 4.9 allowed per game1-4 at home
- W3-2vs St. Louis CardinalsJul 21
- L0-7vs Detroit TigersJul 19
- L1-2vs Detroit TigersJul 18
- L2-4at Minnesota TwinsJul 12
- W4-3at Minnesota TwinsJul 11
- L6-7at Texas RangersJul 10
- W13-1at Texas RangersJul 9
- L3-8at Texas RangersJul 8
- L5-7vs Boston Red SoxJul 6
- L1-8vs Boston Red SoxJul 5
St. Louis Cardinals
Last 10: 4-6Streak L23.7 scored · 3.7 allowed per game2-2 away
- L2-3at Los Angeles AngelsJul 21
- L7-8at Arizona DiamondbacksJul 19
- W5-4at Arizona DiamondbacksJul 18
- L3-4vs Atlanta BravesJul 12
- W2-1vs Atlanta BravesJul 11
- L4-8vs Milwaukee BrewersJul 9
- W5-1vs Milwaukee BrewersJul 8
- L3-4vs Milwaukee BrewersJul 7
- L3-4vs Milwaukee BrewersJul 6
- W3-0at Chicago CubsJul 5
Standings
| Team | Games behind | Lost | Streak | Win % | Won |
|---|---|---|---|---|---|
| Milwaukee | - | 53 | W2 | .621 | 87 |
| Chicago | 9 | 62 | L2 | .557 | 78 |
| St. Louis | 17 | 70 | W2 | .500 | 70 |
| Pittsburgh | 19 | 72 | L1 | .486 | 68 |
| Cincinnati | 20 | 73 | W2 | .479 | 67 |
| Houston | - | 69 | W1 | .507 | 71 |
| Texas | 2 | 71 | L1 | .493 | 69 |
| Seattle | 5 | 74 | W2 | .471 | 66 |
| Athletics | 17 | 86 | W1 | .386 | 54 |
| Los Angeles | 18 | 87 | L2 | .379 | 53 |
How the scoring went
- 6th Inning1-0Wetherholt homered to center (409 feet).
Win probability
Above the line favours Los Angeles Angels, below favours St. Louis Cardinals.
Venue
- Angel StadiumAnaheim, California
- Attendance25187
- OfficialsDan Bellino, Dexter Kelley, Shane Livensparger, Mark Ripperger
Elsewhere
Picks for MLB
MLB rules and settlement
These two, other days
- Angels Secure Series Win Over Cardinals 5-1Jul 21, 2026
- Angels Edge Cardinals in Close Contest at HomeJul 20, 2026