Cardinals Edge Padres in Close Contest at Petco Park
Thursday, May 7, 2026, 10:00 PM ET · Petco Park
St. Louis Cardinals 2, San Diego Padres 1, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.
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Quick answers
Who won St. Louis Cardinals vs San Diego Padres?
St. Louis Cardinals beat San Diego Padres 2-1 at Petco Park on May 7, 2026.
Who was favored in St. Louis Cardinals vs San Diego Padres?
San Diego Padres were the favorite at DraftKings, moneyline -169 (about 63% implied). The underdog won.
In a tightly contested game at Petco Park, the St. Louis Cardinals triumphed over the San Diego Padres with a final score of 2-1. This victory not only allowed the Cardinals to take a lead in the series, which is now tied at 2-2, but also showcased their resilience and ability to perform under pressure. Both teams entered the match with identical records of 22-15, emphasizing the competitive nature of this matchup.
The Padres have struggled recently, holding a record of 4-6 in their last ten games, with an average of 4.3 runs scored per game and 5.9 runs allowed. Their most recent game saw them secure a win against the San Francisco Giants on May 6, with a score of 10-5. However, prior to that, they faced a series of defeats, including a 0-4 loss to the Chicago White Sox on May 3 and a 2-8 loss to the same team the day before. At home, the Padres have struggled, with a home record of 1-3 in their last four games, averaging only 3.4 runs scored while allowing 5.6 runs.
Conversely, the Cardinals have fared better in their recent outings, achieving a record of 6-3-1 over their last ten games, with an average of 4.8 runs scored and 3.6 runs allowed. Their last game resulted in a loss to the Milwaukee Brewers, where they fell 2-6 on May 6. Prior to that, they enjoyed a successful stretch, including a 6-3 victory against the Brewers on May 4 and a 7-2 win against the Los Angeles Dodgers on May 2. The Cardinals have performed well on the road, boasting a perfect away record of 4-0 in their last four games.
In terms of previous meetings, the Cardinals and Padres have faced each other six times in the last season, with both teams winning three games each. Their last encounter before this game was on August 3, 2025, where the Padres lost 5-8 at home. The history between these two teams adds an intriguing layer to their matchups, as they are closely matched.
Injuries have impacted both rosters, with the Padres missing several key players. Jason Adam is on the 60-day injured list due to a shoulder issue, while Miguel Andujar and Gavin Sheets are both on the 10-day injured list with wrist and foot injuries, respectively. Jeremiah Estrada is also on the 15-day injured list with a shoulder problem, and Lucas Giolito is dealing with an elbow injury, also on the 60-day injured list. The Cardinals have their own injury concerns, with Everson Pereira on the 10-day injured list due to a hand injury and Masyn Winn also on the 10-day injured list with a thumb issue. Ramon Urias is listed as day-to-day with an arm injury, while Andre Pallante and JJ Wetherholt are on the 15-day and 10-day injured lists, respectively, with elbow and wrist injuries.
The betting market, as provided by DraftKings, favored the Padres with odds of -169 on the moneyline, while the Cardinals were set at +139. The spread was -1.5 for the Padres, with a total set at 8.0, and both the over and under odds were listed at -110. These odds reflect the competitive nature of the matchup and the expectations surrounding both teams.
The weather conditions during the game were typical for San Diego, providing a favorable environment for baseball, which likely contributed to the performance of both teams.
Key moments in the game included an early score from the Padres in the first inning when Xander Bogaerts singled to right, allowing Manny Machado to score and Fernando Tatis Jr. to advance to third. The Cardinals responded in the fourth inning with a homer from Burleson, bringing the score to 1-1. The decisive moment came in the seventh inning when Winn tripled to right, scoring Walker and giving the Cardinals a 2-1 lead that they would hold onto until the end.
As the game concluded, the Padres' chances of winning were effectively diminished, with a final home win probability of 0.0%. This match not only highlighted the strengths and weaknesses of both teams but also set the stage for their continued rivalry in the series.
Odds
| Book | Spread | Total | Moneyline |
|---|---|---|---|
| DraftKings | SD -169 | 8 o -110 / u -110 | St. Louis Cardinals +139 · San Diego Padres -169 |
Injury report
- Jason Adam60-Day-ILShoulderSan Diego Padres
- Miguel Andujar10-Day-ILWristSan Diego Padres
- Gavin Sheets10-Day-ILFootSan Diego Padres
- Jeremiah Estrada15-Day-ILShoulderSan Diego Padres
- Lucas Giolito60-Day-ILElbowSan Diego Padres
- Everson Pereira10-Day-ILHandSt. Louis Cardinals
- Ramon UriasDay-To-DayArmSt. Louis Cardinals
- Masyn Winn10-Day-ILThumbSt. Louis Cardinals
- Andre Pallante15-Day-ILElbowSt. Louis Cardinals
- JJ Wetherholt10-Day-ILWristSt. Louis Cardinals
Recent form
San Diego Padres
Last 10: 4-6Streak W14.3 scored · 5.9 allowed per game1-3 at home
- W10-5at San Francisco GiantsMay 6
- L2-3at San Francisco GiantsMay 5
- L0-4vs Chicago White SoxMay 3
- L2-8vs Chicago White SoxMay 2
- L3-8vs Chicago CubsApr 29
- W9-7vs Chicago CubsApr 28
- L7-12at Arizona DiamondbacksApr 26
- W6-4at Arizona DiamondbacksApr 25
- L3-8at Colorado RockiesApr 23
- W1-0at Colorado RockiesApr 22
St. Louis Cardinals
Last 10: 6-3-1Streak L14.8 scored · 3.6 allowed per game4-0 away
- L2-6vs Milwaukee BrewersMay 6
- D0-0vs Milwaukee BrewersMay 5
- W6-3vs Milwaukee BrewersMay 4
- L1-4vs Los Angeles DodgersMay 3
- W7-2vs Los Angeles DodgersMay 2
- W10-5at Pittsburgh PiratesApr 30
- W5-4at Pittsburgh PiratesApr 29
- W11-7at Pittsburgh PiratesApr 28
- W4-2at Pittsburgh PiratesApr 27
- L2-3vs Seattle MarinersApr 26
Standings
| Team | Games behind | Lost | Streak | Win % | Won |
|---|---|---|---|---|---|
| Milwaukee | - | 53 | W2 | .621 | 87 |
| Chicago | 9 | 62 | L2 | .557 | 78 |
| St. Louis | 17 | 70 | W2 | .500 | 70 |
| Pittsburgh | 19 | 72 | L1 | .486 | 68 |
| Cincinnati | 20 | 73 | W2 | .479 | 67 |
| Los Angeles | - | 57 | L2 | .590 | 82 |
| Arizona | 9 | 67 | W1 | .525 | 74 |
| San Diego | 9.5 | 67 | L2 | .521 | 73 |
| San Francisco | 24.5 | 82 | W1 | .414 | 58 |
| Colorado | 28.5 | 86 | W2 | .386 | 54 |
How the scoring went
- 1st Inning0-1Bogaerts singled to right, Machado scored, Tatis Jr. to third.
- 4th Inning1-1Burleson homered to right (378 feet).
- 7th Inning2-1Winn tripled to right, Walker scored.
Win probability
Above the line favours San Diego Padres, below favours St. Louis Cardinals.
Venue
- Petco ParkSan Diego, California
- Attendance44966
- OfficialsAlex Tosi, Cory Blaser, Jansen Visconti, Andy Fletcher