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MLB · Final

White Sox Dominate Padres in 8-2 Victory

Friday, May 1, 2026, 9:40 PM ET · Petco Park

Chicago White Sox 8, San Diego Padres 2, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Chicago White Sox vs San Diego Padres?

Chicago White Sox beat San Diego Padres 8-2 at Petco Park on May 1, 2026.

Who was favored in Chicago White Sox vs San Diego Padres?

San Diego Padres were the favorite at DraftKings, moneyline -149 (about 60% implied). The underdog won.

In a decisive matchup at Petco Park, the Chicago White Sox triumphed over the San Diego Padres with a final score of 8-2. This victory allowed the White Sox to win the series 2-1 against the Padres, showcasing their strength in recent games. The White Sox have been on a roll, boasting a record of 7-3 in their last ten games, including a three-game winning streak. They have averaged 5.9 runs scored per game while allowing only 4.5, highlighting their offensive prowess and solid pitching.

In contrast, the Padres have struggled recently, with a record of 6-4 over their last ten games and a current losing streak of one. They have averaged 4.5 runs scored per game but have allowed 5.6, indicating defensive challenges that have contributed to their recent form. The Padres' home record stands at 19-12, while the White Sox have a 15-17 record away from home.

The game began with the White Sox taking control in the second inning, scoring six runs. Antonacci kicked off the scoring with a single that brought Montgomery home, followed by Hays scoring on a fielder's choice. Benintendi added to the lead with a sacrifice fly, and Murakami capped the inning with a powerful home run that scored Peters and Romo. By the end of the second inning, the White Sox had established a commanding 6-0 lead.

The White Sox continued to put pressure on the Padres, with Montgomery hitting another home run in the fifth inning, extending the lead to 7-0. The Padres managed to score their first run in the eighth inning when Andujar reached on an infield single, allowing Johnson to cross home plate. Machado followed suit, bringing Tatis Jr. home, but it was not enough to close the gap significantly.

In terms of injuries, the Padres were missing several key players, including Jason Adam, who is on the 60-day injured list with a shoulder injury, and Miguel Andujar, who is on the 10-day injured list due to a wrist issue. The White Sox also faced injury challenges, with Chris Murphy on the 15-day injured list for a forearm issue and Tanner Murray on the 60-day injured list with a shoulder injury.

The betting odds from DraftKings indicated the Padres as -149 favorites, with a spread of -1.5 and a total set at 8.0. The over odds were at -117, while the under odds were at -103. The conditions at Petco Park were conducive to a competitive game, but the White Sox's early offensive explosion set the tone.

This matchup was noteworthy not only for the scoreline but also for the implications it has on both teams moving forward. The White Sox's ability to capitalize on scoring opportunities and their strong pitching will be crucial as they look to maintain their momentum. Meanwhile, the Padres will need to address their defensive lapses and find ways to improve their scoring efficiency if they hope to bounce back in upcoming games.

Odds

BookSpreadTotalMoneyline
DraftKingsSD -149 8 o -117 / u -103 Chicago White Sox +124 · San Diego Padres -149

What these prices pay on $100 · What these numbers mean

Injury report

  • Jason Adam60-Day-ILShoulderSan Diego Padres
  • Miguel Andujar10-Day-ILWristSan Diego Padres
  • Gavin Sheets10-Day-ILFootSan Diego Padres
  • Jeremiah Estrada15-Day-ILShoulderSan Diego Padres
  • Lucas Giolito60-Day-ILElbowSan Diego Padres
  • Chris Murphy15-Day-ILForearmChicago White Sox
  • Kyle Teel10-Day-ILAnkleChicago White Sox
  • Tanner Murray60-Day-ILShoulderChicago White Sox
  • Drew Thorpe60-Day-ILElbowChicago White Sox
  • Huascar Brazoban15-Day-ILLatChicago White Sox

Recent form

San Diego Padres

Last 10: 6-4Streak L14.5 scored · 5.6 allowed per game3-1 at home

  • L3-8vs Chicago CubsApr 29
  • W9-7vs Chicago CubsApr 28
  • L7-12at Arizona DiamondbacksApr 26
  • W6-4at Arizona DiamondbacksApr 25
  • L3-8at Colorado RockiesApr 23
  • W1-0at Colorado RockiesApr 22
  • W4-1at Los Angeles AngelsApr 19
  • L0-8at Los Angeles AngelsApr 18
  • W5-2vs Seattle MarinersApr 17
  • W7-6vs Seattle MarinersApr 16

Chicago White Sox

Last 10: 7-3Streak W35.9 scored · 4.5 allowed per game3-1 away

  • W3-2vs Los Angeles AngelsApr 29
  • W5-2vs Los Angeles AngelsApr 28
  • W8-7vs Los Angeles AngelsApr 27
  • L1-2vs Washington NationalsApr 26
  • L3-6vs Washington NationalsApr 25
  • W5-4vs Washington NationalsApr 24
  • L7-11at Arizona DiamondbacksApr 23
  • W11-5at Arizona DiamondbacksApr 22
  • W7-4at AthleticsApr 19
  • W9-2at AthleticsApr 18

Standings

TeamGames behindLostStreakWin %Won
Chicago-66L1.52573
Cleveland369L1.50470
Minnesota6.573L1.47967
Detroit975W1.46064
Kansas City11.578L3.44362
Los Angeles-57L2.59082
Arizona967W1.52574
San Diego9.567L2.52173
San Francisco24.582W1.41458
Colorado28.586W2.38654

How the scoring went

  1. 2nd Inning1-0Antonacci singled to right, Montgomery scored, Meidroth to third.
  2. 2nd Inning2-0Hays grounded into fielder's choice to third, Meidroth scored, Antonacci out at second.
  3. 2nd Inning3-0Benintendi hit sacrifice fly to center, Hays scored, Peters to third.
  4. 2nd Inning6-0Murakami homered to right center (413 feet), Peters scored and Romo scored.
  5. 5th Inning7-0Montgomery homered to right center (385 feet).
  6. 8th Inning8-0Peters singled to center, Antonacci scored, Hays to second.
  7. 8th Inning8-1Andujar reached on infield single to shortstop, Johnson scored, Tatis Jr. to second.
  8. 8th Inning8-2Machado singled to left, Tatis Jr. scored, Andujar to second.

Win probability

Above the line favours San Diego Padres, below favours Chicago White Sox.

Venue

  • Petco ParkSan Diego, California
  • Attendance43638
  • OfficialsJames Hoye, Sean Barber, John Libka, D.J. Reyburn

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.