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MLB · Final

White Sox Defeat Padres 4-0 in San Diego

Saturday, May 2, 2026, 8:40 PM ET · Petco Park

Chicago White Sox 4, San Diego Padres 0, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Chicago White Sox vs San Diego Padres?

Chicago White Sox beat San Diego Padres 4-0 at Petco Park on May 2, 2026.

Who was favored in Chicago White Sox vs San Diego Padres?

San Diego Padres were the favorite at DraftKings, moneyline -192 (about 66% implied). The underdog won.

In a decisive victory, the Chicago White Sox defeated the San Diego Padres 4-0 at Petco Park, clinching the series 2-1. This match showcased the White Sox's recent strong form, extending their winning streak to five games. They have recorded a 7-3 record over their last ten games, averaging 5.8 runs scored while allowing just 4.5 runs per game. In contrast, the Padres have struggled, finishing their last ten games with a 5-5 record and experiencing a two-game losing streak. The Padres averaged 4.0 runs scored and allowed 5.8 runs during this stretch.

The game saw the White Sox capitalize on their scoring opportunities, with key plays coming in the sixth and seventh innings. In the sixth, Vargas singled to right, bringing Peters and Benintendi across the plate. The seventh inning saw Quero single to right, scoring Meidroth, followed by a sacrifice bunt by Peters that allowed Antonacci to score, bringing the total to four runs for Chicago.

The White Sox's away record stands at 16-17, while the Padres have a home record of 19-13. Historically, the teams are now tied 2-2 in their last four meetings, with the most recent encounter on May 2, 2026, also resulting in a win for the White Sox, who took that game 8-2.

In terms of injuries, the Padres are facing significant challenges with multiple players on the injured list, including Jason Adam (60-Day IL, Shoulder), Miguel Andujar (10-Day IL, Wrist), Gavin Sheets (10-Day IL, Foot), and Jeremiah Estrada (15-Day IL, Shoulder). The White Sox are also dealing with injuries, with Chris Murphy (15-Day IL, Forearm), Kyle Teel (10-Day IL, Ankle), Tanner Murray (60-Day IL, Shoulder), Drew Thorpe (60-Day IL, Elbow), and Huascar Brazoban (15-Day IL, Lat) unavailable.

The betting market, as reported by DraftKings, had the Padres favored at -192 with a spread of -1.5 and a total set at 8.0. The odds for the over were -107, while the under was -113. The White Sox were priced at +157 on the money line.

The game was played under clear conditions, which typically favor offense in baseball. Viewers should have noted the White Sox's ability to execute in critical moments, as well as the Padres' struggles to capitalize on their opportunities, which ultimately led to their shutout in this matchup.

Odds

BookSpreadTotalMoneyline
DraftKingsSD -192 8 o -107 / u -113 Chicago White Sox +157 · San Diego Padres -192

What these prices pay on $100 · What these numbers mean

Injury report

  • Jason Adam60-Day-ILShoulderSan Diego Padres
  • Miguel Andujar10-Day-ILWristSan Diego Padres
  • Gavin Sheets10-Day-ILFootSan Diego Padres
  • Jeremiah Estrada15-Day-ILShoulderSan Diego Padres
  • Lucas Giolito60-Day-ILElbowSan Diego Padres
  • Chris Murphy15-Day-ILForearmChicago White Sox
  • Kyle Teel10-Day-ILAnkleChicago White Sox
  • Tanner Murray60-Day-ILShoulderChicago White Sox
  • Drew Thorpe60-Day-ILElbowChicago White Sox
  • Huascar Brazoban15-Day-ILLatChicago White Sox

Recent form

San Diego Padres

Last 10: 5-5Streak L24 scored · 5.8 allowed per game2-2 at home

  • L2-8vs Chicago White SoxMay 2
  • L3-8vs Chicago CubsApr 29
  • W9-7vs Chicago CubsApr 28
  • L7-12at Arizona DiamondbacksApr 26
  • W6-4at Arizona DiamondbacksApr 25
  • L3-8at Colorado RockiesApr 23
  • W1-0at Colorado RockiesApr 22
  • W4-1at Los Angeles AngelsApr 19
  • L0-8at Los Angeles AngelsApr 18
  • W5-2vs Seattle MarinersApr 17

Chicago White Sox

Last 10: 7-3Streak W45.8 scored · 4.5 allowed per game3-1 away

  • W8-2at San Diego PadresMay 2
  • W3-2vs Los Angeles AngelsApr 29
  • W5-2vs Los Angeles AngelsApr 28
  • W8-7vs Los Angeles AngelsApr 27
  • L1-2vs Washington NationalsApr 26
  • L3-6vs Washington NationalsApr 25
  • W5-4vs Washington NationalsApr 24
  • L7-11at Arizona DiamondbacksApr 23
  • W11-5at Arizona DiamondbacksApr 22
  • W7-4at AthleticsApr 19

Standings

TeamGames behindLostStreakWin %Won
Chicago-66L1.52573
Cleveland369L1.50470
Minnesota6.573L1.47967
Detroit975W1.46064
Kansas City11.578L3.44362
Los Angeles-57L2.59082
Arizona967W1.52574
San Diego9.567L2.52173
San Francisco24.582W1.41458
Colorado28.586W2.38654

How the scoring went

  1. 6th Inning2-0Vargas singled to right, Peters scored and Benintendi scored.
  2. 7th Inning3-0Quero singled to right, Meidroth scored, Antonacci to third.
  3. 7th Inning4-0Peters hit sacrifice bunt to first, Antonacci scored, Quero to second.

Win probability

Above the line favours San Diego Padres, below favours Chicago White Sox.

Venue

  • Petco ParkSan Diego, California
  • Attendance42758
  • OfficialsSean Barber, John Libka, D.J. Reyburn, James Hoye

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.