MLB · Final

Cardinals Triumph Over White Sox 7-3 at Busch Stadium

Chicago White Sox75-72

St. Louis Cardinals73-75

Friday, September 11, 2026, 8:15 PM ET · Busch Stadium

Quick answers

Who won Chicago White Sox vs St. Louis Cardinals?

St. Louis Cardinals beat Chicago White Sox 7-3 at Busch Stadium on September 11, 2026.

Who was favored in Chicago White Sox vs St. Louis Cardinals?

Chicago White Sox were the favorite at DraftKings, moneyline -111 (about 53% implied). The underdog won.

The St. Louis Cardinals secured a convincing 7-3 victory over the Chicago White Sox at Busch Stadium, marking their second consecutive win in this series, which they now lead 2-0. The Cardinals, with a home record of 73-75, have been struggling recently, having lost their last three games prior to this matchup. However, they managed to turn their fortunes around against the White Sox, who are now 75-72 for the season and have also faced difficulties, losing their last three games leading up to this contest.

In the game, the Cardinals showcased their offensive prowess, scoring seven runs against the White Sox's pitching staff. The scoring opened in the second inning when Winn grounded into a fielder's choice, allowing Bernal to score. The White Sox quickly responded in the third inning with Meidroth hitting a home run to left center, leveling the game at 2-2. However, the Cardinals regained the lead shortly after, with Báez driving in Walker and later contributing to a series of runs in the fifth inning, where Burleson, Báez, and Bernal all crossed home plate, extending their lead to 6-2. The Cardinals continued to build on their advantage, with Bernal scoring again in the seventh inning. The White Sox managed to add one more run in the eighth inning, but it was not enough to threaten the Cardinals' lead.

The Cardinals' recent form had seen them average 5.7 runs scored and 5.1 runs allowed over their last ten games, which included a record of 5-5. Despite their recent struggles, they were able to capitalize on their home advantage, where they hold a record of 2-1 in their last three home games. The White Sox, on the other hand, have averaged only 3.2 runs scored and 3.7 runs allowed in their last ten games, with a record of 3-7, and they have struggled particularly in away games, holding a 1-3 record in their last four.

In terms of injuries, the Cardinals were missing several key players, including Peter Strzelecki, who is on the 15-Day Injured List due to a forearm issue, and JJ Wetherholt, Everson Pereira, Blaze Jordan, and Hunter Dobbins, all of whom are also on the Injured List with various ailments. The White Sox had their own injury concerns, with Drew Thorpe on the 60-Day Injured List due to an elbow injury, Huascar Brazoban on the 15-Day Injured List with a lat issue, and Tommy Pham on the 10-Day Injured List due to a calf injury, among others.

The betting market reflected a competitive matchup, with DraftKings listing the White Sox at -111 and the Cardinals at -109 on the moneyline. The total for the game was set at 7.5, with the over at -119 and the under at -101. This indicates that the market anticipated a closely contested game, which ultimately played out with the Cardinals emerging as the stronger side.

Conditions at Busch Stadium were favorable for baseball, contributing to an engaging atmosphere for fans. Viewers were treated to a display of offensive talent, particularly from the Cardinals, who effectively capitalized on their scoring opportunities. The game featured several pivotal moments, including key hits from Báez and Bernal that helped secure the victory.

Overall, the Cardinals' performance was a much-needed boost as they look to finish the season strong, while the White Sox will need to regroup after this defeat as they continue their road trip.

What we said beforehand

The St. Louis Cardinals will face off against the Chicago White Sox at Busch Stadium on September 12, 2026. This matchup is particularly interesting as both teams are currently struggling, with the Cardinals holding a record of 72-75 and the White Sox at 75-71. The stakes are high for both teams as they look to improve their standings in the league.

The Cardinals have had a challenging last five games, losing all but one, with their most recent results being a loss to the San Francisco Giants by a score of 2-1, followed by two more losses to the same team, 5-4 in 11 innings and 7-6. Over their last five games, the Cardinals have an average of 4.2 runs scored per game while allowing 5.2 runs. At home, they have a record of 5-5 in their last ten games, but they are currently on a three-game losing streak.

In contrast, the White Sox have also faced difficulties, losing their last three games against the Pittsburgh Pirates, including a 2-0 loss in their latest outing. In their last five games, they have averaged 3.8 runs scored per game and allowed 4.4 runs. Their recent form shows a record of 3-7 over their last ten games, indicating that both teams are in need of a turnaround.

When it comes to home and away performance, the Cardinals have a home record of 2-1 in their last three games, while the White Sox have struggled on the road with a 1-3 record in their last four away games. This could play a significant role in the outcome of the game as the Cardinals aim to leverage their home advantage.

In terms of previous meetings, the Cardinals and White Sox have faced each other three times in the 2025 season, with the Cardinals winning two of those games, including a close 5-4 victory and a dominant 12-2 win. The most recent meeting ended in a draw, 0-0, showcasing the competitive nature of their encounters.

Injuries are also a factor in this matchup. The Cardinals will be without several key players, including Peter Strzelecki (forearm, 15-Day IL), JJ Wetherholt (wrist, 10-Day IL), Everson Pereira (hand, 10-Day IL), Blaze Jordan (ankle, 10-Day IL), and Hunter Dobbins (elbow, 15-Day IL). The White Sox are missing Drew Thorpe (elbow, 60-Day IL), Huascar Brazoban (lat, 15-Day IL), Tyler Davis (bereavement), Tanner Murray (shoulder, 60-Day IL), and Tommy Pham (calf, 10-Day IL). These injuries could impact both teams' performance and depth.

The betting market, as provided by DraftKings, has set the odds with the Cardinals at -112 and the White Sox at -108, indicating a closely contested matchup. The spread is set at 1.5, with a total of 7.5 runs for the game. The over odds are at -118.0, while the under odds are at -102.0, reflecting the uncertainty surrounding the offensive capabilities of both teams.

Weather conditions for the game are expected to be warm, with a temperature of 81°F and a 75% chance of precipitation, along with wind gusts reaching 7 mph. These factors could influence gameplay, particularly in terms of pitching and fielding.

Viewers should watch for key performances from standout players. For the Cardinals, Alec Burleson leads in batting average at .283 and has 104 runs batted in, while Jordan Walker has hit 28 home runs. For the White Sox, Chase Meidroth has a batting average of .267, Munetaka Murakami leads with 31 home runs, and Colson Montgomery has driven in 83 runs. These players could be pivotal in determining the outcome of this matchup.

Odds

Book	Spread	Total	Moneyline
DraftKings	CHW -111	7.5 o -119 / u -101	Chicago White Sox -111 · St. Louis Cardinals -109

What these prices pay on $100 · What these numbers mean

Injury report

Peter Strzelecki15-Day-ILForearmSt. Louis Cardinals
JJ Wetherholt10-Day-ILWristSt. Louis Cardinals
Everson Pereira10-Day-ILHandSt. Louis Cardinals
Blaze Jordan10-Day-ILAnkleSt. Louis Cardinals
Hunter Dobbins15-Day-ILElbowSt. Louis Cardinals
Drew Thorpe60-Day-ILElbowChicago White Sox
Huascar Brazoban15-Day-ILLatChicago White Sox
Tyler DavisbereavementPersonalChicago White Sox
Tanner Murray60-Day-ILShoulderChicago White Sox
Tommy Pham10-Day-ILCalfChicago White Sox

Recent form

St. Louis Cardinals

Last 10: 5-5Streak L35.7 scored · 5.1 allowed per game2-1 at home

L1-2at San Francisco GiantsSep 9
L4-5at San Francisco GiantsSep 8
L7-10at Colorado RockiesSep 6
W7-6at Colorado RockiesSep 5
L2-3at Los Angeles DodgersSep 4
W8-6at Los Angeles DodgersSep 3
W13-8at Los Angeles DodgersSep 2
L4-5vs Pittsburgh PiratesAug 30
W4-1vs Pittsburgh PiratesAug 29
W7-5vs Baltimore OriolesAug 27

Chicago White Sox

Last 10: 3-7Streak L33.2 scored · 3.7 allowed per game1-3 away

L0-2vs Pittsburgh PiratesSep 10
L2-4vs Pittsburgh PiratesSep 9
L3-9vs Pittsburgh PiratesSep 8
W10-1vs Minnesota TwinsSep 6
L4-6vs Minnesota TwinsSep 5
W4-1vs Minnesota TwinsSep 4
L0-2at Houston AstrosSep 3
W5-1at Houston AstrosSep 2
L3-6at Houston AstrosSep 1
L1-5at Minnesota TwinsAug 30

Standings

Team	Games behind	Lost	Streak	Win %	Won
Chicago	-	72	L4	.510	75
Cleveland	0.5	73	W1	.507	75
Minnesota	6	78	L2	.469	69
Detroit	7	79	W2	.463	68
Kansas City	9.5	82	W2	.446	66
Milwaukee	-	56	W4	.622	92
Chicago	10	66	W1	.554	82
Pittsburgh	18	74	L1	.500	74
St. Louis	19	75	W1	.493	73
Cincinnati	22.5	78	L4	.469	69

How the scoring went

1st Inning1-0Meidroth homered to center (398 feet).
1st Inning1-1Burleson doubled to right, Herrera scored.
2nd Inning1-2Winn grounded into fielder's choice to third, Bernal scored, Saggese out at second.
3rd Inning2-2Meidroth homered to left center (391 feet).
3rd Inning2-3Báez singled to center, Walker scored, Báez to second.
5th Inning2-4Burleson singled to center, Walker scored.
5th Inning2-5Báez doubled to left, Burleson scored.
5th Inning2-6Bernal singled to left, Báez scored.
7th Inning2-7Bernal singled to left, Báez scored.
8th Inning3-7Murakami grounded into fielder's choice to first, Antonacci scored, Teel out at second.