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MLB · Final

Cardinals Secure Series Win Over White Sox

Sunday, September 13, 2026, 2:15 PM ET · Busch Stadium

St. Louis Cardinals 3, Chicago White Sox 1, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Chicago White Sox vs St. Louis Cardinals?

St. Louis Cardinals beat Chicago White Sox 3-1 at Busch Stadium on September 13, 2026.

Who was favored in Chicago White Sox vs St. Louis Cardinals?

Chicago White Sox were the favorite at DraftKings, moneyline -120 (about 55% implied). The underdog won.

In a decisive matchup at Busch Stadium, the St. Louis Cardinals defeated the Chicago White Sox with a final score of 3-1, clinching the series 2-1. This victory highlights the Cardinals' ability to capitalize on their home advantage, as they improved their home record to 2-1 in this series. The Cardinals' recent form has shown a balanced performance, with a record of 5-5 over their last ten games and an average of 5.7 runs scored per game while allowing 4.9 runs. Their latest win against the White Sox on September 12, where they triumphed 7-3, set the stage for this game, showcasing their offensive capabilities.

The White Sox, on the other hand, have struggled recently, losing four consecutive games and holding a record of 3-7 in their last ten outings. They have averaged 3.4 runs scored per game while allowing 3.9 runs, indicating a slight struggle in both offensive and defensive aspects. Their last game before facing the Cardinals resulted in a 3-7 loss, further emphasizing their current difficulties.

At home, the Cardinals have performed well, with a home record of 74-76, while the White Sox's away record stands at 76-73. The Cardinals' ability to score runs at home has been a key factor in their recent success, and they managed to demonstrate this again in the sixth inning when Burleson doubled to right, bringing in three runs. This pivotal moment shifted the momentum in favor of the Cardinals, who had been trailing after the second inning when Meidroth's sacrifice fly allowed Benintendi to score for the White Sox.

In terms of head-to-head matchups, the Cardinals have had the upper hand in recent encounters, boasting a record of 3-0-1 against the White Sox over the last two seasons. Their victory on September 12 added to a series of successful outings against Chicago, including a 5-4 win on June 19, 2025, and a dominant 12-2 victory on June 17, 2025.

Injury concerns have affected both teams, with the Cardinals missing several players including Peter Strzelecki, who is on the 15-day injured list due to a forearm issue, and JJ Wetherholt, who is on the 10-day injured list with a wrist injury. Other players like Jose Fermin, Everson Pereira, and Blaze Jordan are also dealing with various injuries, impacting the depth of the roster. The White Sox are similarly affected, with Tyler Davis on bereavement leave, Drew Thorpe on the 60-day injured list with an elbow issue, and Tommy Pham on the 10-day injured list due to a calf injury.

The betting market reflected the competitive nature of this matchup, with DraftKings setting the odds for the White Sox at -120 and the Cardinals at -101. The spread was set at 1.5, with a total of 8.5 runs, indicating expectations of a closely contested game.

Conditions at Busch Stadium were favorable for baseball, contributing to the excitement of the game. Fans were treated to a display of solid pitching and timely hitting, particularly from the Cardinals, who capitalized on their opportunities. As the game progressed, viewers could observe the Cardinals' resilience and strategic approach, especially in high-pressure situations, which ultimately led them to victory.

Overall, this game not only showcased the Cardinals' strengths at home but also highlighted the challenges faced by the White Sox as they continue to navigate a difficult stretch in their season.

What we said beforehand

The upcoming matchup between the St. Louis Cardinals and the Chicago White Sox promises to be an intriguing contest, especially as the series is currently tied 1-1. This game will take place at Busch Stadium on September 13, 2026, with a start time of 18:15 UTC. Both teams are looking to gain an edge in this tightly contested series, making this fixture particularly noteworthy for fans and analysts alike.

The St. Louis Cardinals enter this game with a home record of 73-76, while the Chicago White Sox boast a slightly better away record of 76-72. Recent form shows the Cardinals have struggled, losing four out of their last five games. Their last five results include a win against the White Sox (7-3) and three consecutive losses to the San Francisco Giants (5-4 F/11, 2-1, 7-6). The Cardinals have averaged 5.2 runs scored and allowed 5.2 runs in their last five games.

In contrast, the Chicago White Sox have also faced difficulties, losing four consecutive games in their last five outings. Their recent results include a loss to the Cardinals (7-3) and three losses to the Pittsburgh Pirates (9-3, 4-2, and 2-0). The White Sox have averaged only 3.6 runs scored while allowing 4.6 runs in their last five games, indicating a significant drop in offensive performance.

When it comes to home and away performance, the Cardinals have a balanced record of 5-5 in their last ten home games, with an average of 5.7 runs scored and 4.9 runs allowed. The White Sox, however, have struggled on the road, recording a 3-7 record in their last ten away games, with a lower scoring average of 3.4 runs and 3.9 runs allowed.

Historically, the Cardinals have had the upper hand in recent meetings, holding a record of 3-0-1 against the White Sox in their last four encounters, including a win in their most recent game on September 12, 2026. The previous meetings this season have seen the Cardinals winning decisively, including a 12-2 victory in June 2025.

In terms of injuries, the Cardinals will be without Peter Strzelecki (forearm, 15-Day IL), JJ Wetherholt (wrist, 10-Day IL), and Everson Pereira (hand, 10-Day IL). Additionally, Jose Fermin is listed as day-to-day with an undisclosed issue, and Blaze Jordan is also on the 10-Day IL due to an ankle injury. The White Sox are dealing with their own injury concerns, including Tyler Davis (bereavement), Drew Thorpe (elbow, 60-Day IL), Tommy Pham (calf, 10-Day IL), Huascar Brazoban (lat, 15-Day IL), and Tanner Murray (shoulder, 60-Day IL).

The betting market reflects the competitive nature of this matchup, with DraftKings listing the White Sox as slight favorites at -117 on the moneyline, while the Cardinals are priced at -103. The spread is set at 1.5, with a total of 8.5 runs for the game. The odds for the over are -120, while the under is at -101.

Weather conditions at Busch Stadium are expected to be favorable for baseball, with a temperature of 81°F and no precipitation forecasted. Wind gusts may reach up to 9 mph, which could affect gameplay but are not expected to be significant.

As this game unfolds, viewers should keep an eye on the performance of key players. For the Cardinals, Alec Burleson leads in batting average at .282 and has driven in 106 runs, while Jordan Walker has hit 28 home runs. For the White Sox, Sam Antonacci holds a batting average of .269, and Munetaka Murakami has contributed 31 home runs this season. The outcomes of these individual performances could play a crucial role in determining the winner of this tightly contested series.

Odds

BookSpreadTotalMoneyline
DraftKingsCHW -120 8.5 o -122 / u +101 Chicago White Sox -120 · St. Louis Cardinals -101

What these prices pay on $100 · What these numbers mean

Injury report

  • Peter Strzelecki15-Day-ILForearmSt. Louis Cardinals
  • JJ Wetherholt10-Day-ILWristSt. Louis Cardinals
  • Jose FerminDay-To-DayUndisclosedSt. Louis Cardinals
  • Everson Pereira10-Day-ILHandSt. Louis Cardinals
  • Blaze Jordan10-Day-ILAnkleSt. Louis Cardinals
  • Tyler DavisbereavementPersonalChicago White Sox
  • Drew Thorpe60-Day-ILElbowChicago White Sox
  • Tommy Pham10-Day-ILCalfChicago White Sox
  • Huascar Brazoban15-Day-ILLatChicago White Sox
  • Tanner Murray60-Day-ILShoulderChicago White Sox

Recent form

St. Louis Cardinals

Last 10: 5-5Streak W15.7 scored · 4.9 allowed per game2-1 at home

  • W7-3vs Chicago White SoxSep 12
  • L1-2at San Francisco GiantsSep 9
  • L4-5at San Francisco GiantsSep 8
  • L7-10at Colorado RockiesSep 6
  • W7-6at Colorado RockiesSep 5
  • L2-3at Los Angeles DodgersSep 4
  • W8-6at Los Angeles DodgersSep 3
  • W13-8at Los Angeles DodgersSep 2
  • L4-5vs Pittsburgh PiratesAug 30
  • W4-1vs Pittsburgh PiratesAug 29

Chicago White Sox

Last 10: 3-7Streak L43.4 scored · 3.9 allowed per game1-3 away

  • L3-7at St. Louis CardinalsSep 12
  • L0-2vs Pittsburgh PiratesSep 10
  • L2-4vs Pittsburgh PiratesSep 9
  • L3-9vs Pittsburgh PiratesSep 8
  • W10-1vs Minnesota TwinsSep 6
  • L4-6vs Minnesota TwinsSep 5
  • W4-1vs Minnesota TwinsSep 4
  • L0-2at Houston AstrosSep 3
  • W5-1at Houston AstrosSep 2
  • L3-6at Houston AstrosSep 1

Standings

TeamGames behindLostStreakWin %Won
Chicago-73L1.51076
Cleveland174L1.50375
Minnesota5.578W1.47370
Detroit679W4.47070
Kansas City1083L1.44366
Milwaukee-57L1.62093
Chicago9.566W2.55783
Pittsburgh18.575L2.49774
St. Louis1976W1.49374
Cincinnati22.579W1.47070

How the scoring went

  1. 2nd Inning1-0Meidroth hit sacrifice fly to center, Benintendi scored.
  2. 6th Inning1-3Burleson doubled to right, Church scored, Herrera scored and Winn scored.

Win probability

Above the line favours St. Louis Cardinals, below favours Chicago White Sox.

Venue

  • Busch StadiumSt. Louis, Missouri
  • Attendance34609
  • OfficialsMike Estabrook, Malachi Moore, Edwin Jimenez, Alfonso Marquez

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.