Clemson Tigers Edge Louisville Cardinals in Close Contest
Friday, November 14, 2025, 7:30 PM ET · L&N Federal Credit Union Stadium
Clemson Tigers 20, Louisville Cardinals 19, final. Our NCAAF picks are sealed as a hash before kickoff and settled in public, losses included.
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Quick answers
Who won Clemson Tigers vs Louisville Cardinals?
Clemson Tigers beat Louisville Cardinals 20-19 at L&N Federal Credit Union Stadium on November 14, 2025.
In a tightly contested matchup at L&N Federal Credit Union Stadium, the Clemson Tigers narrowly defeated the Louisville Cardinals with a final score of 20-19. This game was significant as it showcased the competitive spirit of both teams, with Clemson improving their record to 6-5 while Louisville fell to 7-4.
The Cardinals entered the game with a strong home record of 4-2 and an overall record of 7-3. They had been performing well recently, boasting a record of 8-2 in their last ten games, although they were on a one-game losing streak after falling to the California Golden Bears 26-29 on November 9. Louisville averaged 33.7 points scored per game while allowing 20.9 points, indicating a solid offensive and defensive performance throughout the season.
On the other hand, the Clemson Tigers came into this game with a record of 5-5, having won their last game against the Florida State Seminoles 24-10. Their recent form showed a record of 5-5 in their last ten games, with an average of 28.5 points scored and 23.3 points allowed. Clemson's away record was notably better than their home performance, standing at 3-1 in away games.
Historically, the two teams had met once before in the 2024 season, where Clemson emerged victorious with a score of 33-21. This previous meeting added an extra layer of anticipation to the rematch, as both teams sought to assert their dominance.
In terms of injuries, the block did not provide specific details about player availability, but such factors often play a crucial role in the outcome of games at this level. The conditions for the match were not detailed, but typically, weather can influence gameplay in college football, affecting the strategies employed by both teams.
The betting market had assessed the matchup, with the home team, Louisville, given a home win probability of 0.0, indicating that the odds were not in their favor leading into the game, as attributed to the provider.
Viewers were treated to a display of resilience from both sides, with Clemson's recent momentum playing a pivotal role in their victory. As the game unfolded, it was evident that both teams were fighting hard, and the outcome was uncertain until the final moments.
Leaders
- Passing yardsMiller Moss19/27, 212 YDSLouisville Cardinals
- Rushing yardsKeyjuan Brown15 CAR, 135 YDSLouisville Cardinals
- Receiving yardsChris Bell5 REC, 79 YDSLouisville Cardinals
- Passing yardsCade Klubnik22/34, 187 YDSClemson Tigers
- Rushing yardsAdam Randall15 CAR, 105 YDS, 2 TDClemson Tigers
- Receiving yardsT.J. Moore6 REC, 68 YDSClemson Tigers
Recent form
Louisville Cardinals
Last 10: 8-2Streak L133.7 scored · 20.9 allowed per game4-2 at home
- L26-29vs California Golden BearsNov 9
- W28-16at Virginia Tech HokiesNov 1
- W38-24vs Boston College EaglesOct 25
- W24-21at Miami HurricanesOct 17
- L27-30vs Virginia CavaliersOct 4
- W34-27at Pittsburgh PanthersSep 27
- W40-17vs Bowling Green FalconsSep 20
- W28-14vs James Madison DukesSep 5
- W51-17vs Eastern Kentucky ColonelsAug 30
- W41-14at Kentucky WildcatsNov 30
Clemson Tigers
Last 10: 5-5Streak W128.5 scored · 23.3 allowed per game3-1 away
- W24-10vs Florida State SeminolesNov 9
- L45-46vs Duke Blue DevilsNov 1
- L24-35vs SMU MustangsOct 18
- W41-10at Boston College EaglesOct 11
- W38-10at North Carolina Tar HeelsOct 4
- L21-34vs Syracuse OrangeSep 20
- L21-24at Georgia Tech Yellow JacketsSep 13
- W27-16vs Troy TrojansSep 6
- L10-17vs LSU TigersAug 30
- W34-31at SMU MustangsDec 8
Standings
| Team | Overall | In conference |
|---|---|---|
| Virginia | 1-0 | 1-0 |
| Florida State | 1-0 | 0-0 |
| North Carolina | 1-0 | 0-0 |
| Stanford | 1-0 | 0-0 |
| Boston College | 0-0 | 0-0 |
| California | 0-0 | 0-0 |
| Clemson | 0-0 | 0-0 |
| Duke | 0-0 | 0-0 |
| Georgia Tech | 0-0 | 0-0 |
| Louisville | 0-0 | 0-0 |
| Miami | 0-0 | 0-0 |
| Pittsburgh | 0-0 | 0-0 |
| SMU | 0-0 | 0-0 |
| Syracuse | 0-0 | 0-0 |
| Virginia Tech | 0-0 | 0-0 |
| Wake Forest | 0-0 | 0-0 |
| NC State | 0-1 | 0-1 |
Box score
| Stat | Clemson Tigers | Louisville Cardinals |
|---|---|---|
| First downs | 19 | 16 |
| Third downs | 1-13 | 2-11 |
| Fourth downs | 2-5 | 0-1 |
| Total yards | 308 | 385 |
| Net passing yards | 187 | 214 |
| Completions | 22/34 | 20/29 |
| Yards per pass | 5.5 | 7.4 |
| Rushing yards | 121 | 171 |
| Rushing attempts | 30 | 30 |
| Yards per rush | 4.0 | 5.7 |
| Penalties | 3-30 | 10-84 |
| Turnovers | 1 | 1 |
| Fumbles lost | 1 | 1 |
| Interceptions thrown | 0 | 0 |
| Time of possession | 30:55 | 29:05 |
Win probability
Above the line favours Louisville Cardinals, below favours Clemson Tigers.
Venue
- L&N Federal Credit Union StadiumLouisville, KY
- Attendance51234
Elsewhere
- No. 14 BYU hosts Utah Tech in season opener for the Cougars
- UCLA visits Cal in season opener for former Pac-12 rivals with new coaches
- Hawkeyes host Northern Illinois in season opener at Kinnick Stadium
- No. 23 Houston opens season at home against Oregon State after 10-win campaign in 2025
- Nebraska opens its 4th season under Matt Rhule with home game against Ohio
- No. 7 Miami opens the season with a cross-country trip to face Stanford
Picks for NCAAF
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