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MLB · Final

Twins Secure Series Win Against Astros with 4-1 Victory

Wednesday, May 20, 2026, 1:40 PM ET · Target Field

Minnesota Twins 4, Houston Astros 1, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Houston Astros vs Minnesota Twins?

Minnesota Twins beat Houston Astros 4-1 at Target Field on May 20, 2026.

Who was favored in Houston Astros vs Minnesota Twins?

Minnesota Twins were the favorite at DraftKings, moneyline -136 (about 58% implied). The favorite won.

The Minnesota Twins triumphed over the Houston Astros with a final score of 4-1 at Target Field, concluding the series with a 2-1 victory over the Astros. This win is significant not only for the Twins as they aim to improve their standing but also for the Astros, who have struggled on the road this season.

In terms of recent form, the Twins have shown a mixed performance, with a record of 6-4 over their last ten games, though they are currently on a one-game losing streak. They averaged 3.9 runs scored per game while allowing 2.9 runs. Their home record stands at 4-4 in the last ten games, while their overall record at home is 23-27. The Astros, on the other hand, have a record of 4-6 in their last ten games, recently snapping a losing streak with a win against the Twins on May 19. They have averaged just 2.5 runs scored per game during this stretch, while allowing 3.9 runs. Their away record is 20-31, indicating difficulties in securing wins outside of their home venue.

The matchup at Target Field was marked by notable scoring plays. The Astros initially took the lead in the second inning when Vázquez singled to center, allowing Dezenzo to score. However, the Twins quickly responded with a home run from Caratini, leveling the game at 1-1. The pivotal moment came in the fourth inning when Kreidler hit a home run to left center, bringing in Caratini and Gray to score, pushing the Twins ahead 4-1.

In terms of head-to-head performance, the Twins have struggled against the Astros recently, holding a record of 2-5 in their last seven meetings. This series showcased the Twins’ ability to bounce back after losing the previous game to the Astros just a day prior.

Injury concerns have also affected both teams. The Twins were without key players including Byron Buxton, Joe Ryan, Austin Martin, Mike Paredes, and Mick Abel, all of whom are currently on the injured list. The Astros are also dealing with injuries to Brice Matthews, Mike Burrows, Carlos Correa, and Brandon Walter, which have impacted their lineup depth.

The market for this matchup, as provided by DraftKings, had the Twins favored at -136 on the money line, with a total set at 7.5 runs. The spread was -1.5 in favor of the Twins, reflecting expectations of a competitive game.

Conditions at Target Field were suitable for baseball, contributing to an engaging atmosphere for fans. Viewers were encouraged to watch for the Twins' offensive capabilities, particularly how they capitalized on the Astros' pitching mistakes, as well as the overall defensive strategies employed by both teams.

With this victory, the Twins not only secured the series win but also showcased their potential to compete effectively, despite the challenges presented by injuries and previous struggles against the Astros.

Odds

BookSpreadTotalMoneyline
DraftKingsMIN -136 7.5 o -114 / u -105 Houston Astros +113 · Minnesota Twins -136

What these prices pay on $100 · What these numbers mean

Injury report

  • Byron Buxton10-Day-ILHipMinnesota Twins
  • Joe Ryan15-Day-ILLower BodyMinnesota Twins
  • Austin Martin10-Day-ILHamstringMinnesota Twins
  • Mike Paredes60-Day-ILObliqueMinnesota Twins
  • Mick Abel60-Day-ILElbowMinnesota Twins
  • Brice Matthews60-Day-ILKneeHouston Astros
  • Mike Burrows15-Day-ILElbowHouston Astros
  • Carlos Correa60-Day-ILAnkleHouston Astros
  • Brandon Walter60-Day-ILElbowHouston Astros

Recent form

Minnesota Twins

Last 10: 6-4Streak L13.9 scored · 2.9 allowed per game4-4 at home

  • L1-2vs Houston AstrosMay 19
  • W6-3vs Houston AstrosMay 18
  • W5-4vs Milwaukee BrewersMay 17
  • L1-2vs Milwaukee BrewersMay 16
  • L2-3vs Milwaukee BrewersMay 15
  • W9-1vs Miami MarlinsMay 14
  • L5-9vs Miami MarlinsMay 13
  • W3-0vs Miami MarlinsMay 12
  • W5-4at Cleveland GuardiansMay 10
  • W2-1at Cleveland GuardiansMay 9

Houston Astros

Last 10: 4-6Streak W12.5 scored · 3.9 allowed per game2-3 away

  • W2-1at Minnesota TwinsMay 19
  • L3-6at Minnesota TwinsMay 18
  • L0-8vs Texas RangersMay 17
  • W2-0vs Texas RangersMay 16
  • W4-3vs Seattle MarinersMay 14
  • L2-10vs Seattle MarinersMay 13
  • L1-3vs Seattle MarinersMay 12
  • L0-5at Cincinnati RedsMay 10
  • L1-3at Cincinnati RedsMay 9
  • W10-0at Cincinnati RedsMay 8

Standings

TeamGames behindLostStreakWin %Won
Houston-69W1.50771
Texas271L1.49369
Seattle574W2.47166
Athletics1786W1.38654
Los Angeles1887L2.37953
Chicago-66L1.52573
Cleveland369L1.50470
Minnesota6.573L1.47967
Detroit975W1.46064
Kansas City11.578L3.44362

How the scoring went

  1. 2nd Inning1-0Vázquez singled to center, Dezenzo scored, Smith to second.
  2. 2nd Inning1-1Caratini homered to center (406 feet).
  3. 4th Inning1-4Kreidler homered to left center (416 feet), Caratini scored and Gray scored.

Win probability

Above the line favours Minnesota Twins, below favours Houston Astros.

Venue

  • Target FieldMinneapolis, Minnesota
  • Attendance23522
  • OfficialsGabe Morales, Emil Jimenez, Marvin Hudson, Doug Eddings

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.