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MLB · Final

Pirates Secure Series Win Over Cardinals

Thursday, September 24, 2026, 12:35 PM ET · PNC Park

Quick answers

Who won St. Louis Cardinals vs Pittsburgh Pirates?

Pittsburgh Pirates beat St. Louis Cardinals 2-1 at PNC Park on September 24, 2026.

Who was favored in St. Louis Cardinals vs Pittsburgh Pirates?

Pittsburgh Pirates were the favorite at DraftKings, moneyline -167 (about 63% implied). The favorite won.

In a tightly contested game, the Pittsburgh Pirates triumphed over the St. Louis Cardinals with a final score of 2-1 at PNC Park. This victory allowed the Pirates to clinch the series 2-1 against their division rivals, showcasing their resilience in the late stages of the season. The game featured a notable performance from both teams, with the Pirates managing to secure the win despite facing several injuries.

The Pirates entered this game with a home record of 81-78, having recently gone 6-4 in their last ten games, although they were on a one-game losing streak after falling to the Cardinals 5-1 the previous day. Their scoring average at home was 4.0 runs per game, while they allowed an average of 3.9 runs. In contrast, the Cardinals, with a record of 77-82, had a mixed performance lately, going 5-5 in their last ten games, but they were coming off a win against the Pirates. The Cardinals averaged 3.2 runs scored per game on the road, while allowing 3.8 runs.

The game began with a strong start from the Cardinals, as Burleson homered to right center in the first inning, giving St. Louis an early 1-0 lead. However, the Pirates quickly responded, with Lowe hitting a single that allowed Cruz to score, leveling the game at 1-1. The decisive moment came in the eighth inning when Horwitz hit a sacrifice fly to center, bringing Simon home and securing the Pirates' 2-1 lead.

In terms of injuries, the Pirates were significantly affected, as they had several players on the injured list, including Esmerlyn Valdez (10-Day IL, hamstring), Isaac Mattson (15-Day IL, hip), Mitch Keller (60-Day IL, shoulder), Braxton Ashcraft (15-Day IL, arm), and Endy Rodriguez (60-Day IL, hip). The Cardinals also faced injury challenges, with Everson Pereira (10-Day IL, hand), Blaze Jordan (10-Day IL, ankle), Joshua Baez (10-Day IL, oblique), Hunter Dobbins (15-Day IL, elbow), and Max Rajcic (60-Day IL, elbow) out of the lineup.

The betting odds provided by DraftKings indicated that the Pirates were favored at -167, with a spread of -1.5 and a total set at 7.0. The over and under were both priced at -110. The conditions at PNC Park were conducive to baseball, and fans were treated to a competitive atmosphere as both teams vied for crucial late-season victories.

Overall, this game highlighted the Pirates' ability to perform under pressure, especially with their recent injury struggles. The victory not only secured a series win but also provided a morale boost as they approach the end of the season. The Cardinals, despite the loss, demonstrated their competitive spirit, especially with their early lead. As the season progresses, both teams will look to build on their performances and address their injury concerns.

What we said beforehand

The upcoming matchup between the Pittsburgh Pirates and the St. Louis Cardinals is set to take place at PNC Park on September 24, 2026, with the series currently tied 1-1. The Pirates hold a home record of 80-78, while the Cardinals come in with a 77-81 away record. This game is significant as both teams look to gain an advantage in their ongoing rivalry, which has seen the Pirates win 11 of the last 24 meetings against the Cardinals in recent seasons.

In their last five games, the Pirates have had a strong showing, winning four out of five, including a recent victory against the Cardinals on September 22, where they won 2-0. However, they faced a setback in their most recent game on September 23, losing 5-1 to the same opponent. Over the last ten games at home, the Pirates have a record of 6-4, averaging 4.0 runs scored and allowing 3.9 runs per game, though they are currently on a one-game losing streak.

Conversely, the Cardinals have shown mixed form, winning three of their last five games, including a victory against the Pirates in their latest encounter on September 23. Their recent performance has given them a 5-5 record over their last ten games, with an average of 3.2 runs scored and 3.8 runs allowed. They are currently on a one-game winning streak, which could provide them with momentum heading into this matchup.

At home, the Pirates have fared well with a 5-3 record over their last ten games, while the Cardinals have struggled on the road, holding a 1-2 record in their last three away games. This could play a crucial role in the outcome of the game as the Pirates look to capitalize on their home advantage.

In terms of injuries, the Pirates will be missing several key players, including Esmerlyn Valdez (10-Day IL, hamstring), Isaac Mattson (15-Day IL, hip), Mitch Keller (60-Day IL, shoulder), Braxton Ashcraft (15-Day IL, arm), and Endy Rodriguez (60-Day IL, hip). The Cardinals also face injury challenges with Everson Pereira (10-Day IL, hand), Blaze Jordan (10-Day IL, ankle), Joshua Baez (10-Day IL, oblique), Hunter Dobbins (15-Day IL, elbow), and Max Rajcic (60-Day IL, elbow) unavailable for the game.

The betting odds provided by DraftKings indicate that the Pirates are favored with a moneyline of -167, while the Cardinals sit at +138. The spread is set at -1.5 for the Pirates, with a total of 7.0 runs for the game, where the over is priced at -105 and the under at -115.

Weather conditions for the game are expected to be mild, with a temperature of 62°F and wind gusts reaching up to 14 mph. There is no precipitation expected, which should allow for a clear game without weather interruptions.

Viewers should watch for the performance of key players, particularly Nick Gonzales for the Pirates, who leads the team with a batting average of .301, and Brandon Lowe, who has hit 34 home runs and driven in 94 runs. For the Cardinals, Alec Burleson is a player to keep an eye on, boasting a .279 batting average and 112 RBIs, while Jordan Walker has contributed 28 home runs this season. How these players perform could significantly impact the game's outcome.

Odds

BookSpreadTotalMoneyline
DraftKingsPIT -167 7 o -110 / u -110 St. Louis Cardinals +138 · Pittsburgh Pirates -167

What these prices pay on $100 · What these numbers mean

Injury report

  • Esmerlyn Valdez10-Day-ILHamstringPittsburgh Pirates
  • Isaac Mattson15-Day-ILHipPittsburgh Pirates
  • Mitch Keller60-Day-ILShoulderPittsburgh Pirates
  • Braxton Ashcraft15-Day-ILArmPittsburgh Pirates
  • Endy Rodriguez60-Day-ILHipPittsburgh Pirates
  • Everson Pereira10-Day-ILHandSt. Louis Cardinals
  • Blaze Jordan10-Day-ILAnkleSt. Louis Cardinals
  • Joshua Baez10-Day-ILObliqueSt. Louis Cardinals
  • Hunter Dobbins15-Day-ILElbowSt. Louis Cardinals
  • Max Rajcic60-Day-ILElbowSt. Louis Cardinals

Recent form

Pittsburgh Pirates

Last 10: 6-4Streak L14 scored · 3.9 allowed per game5-3 at home

  • L1-5vs St. Louis CardinalsSep 23
  • W2-0vs St. Louis CardinalsSep 22
  • W4-3vs Kansas City RoyalsSep 20
  • W6-5vs Kansas City RoyalsSep 19
  • W8-5vs Kansas City RoyalsSep 18
  • W7-4vs Milwaukee BrewersSep 17
  • L4-5vs Milwaukee BrewersSep 16
  • L1-5vs Milwaukee BrewersSep 15
  • W4-3at Chicago CubsSep 13
  • L3-4at Chicago CubsSep 12

St. Louis Cardinals

Last 10: 5-5Streak W13.2 scored · 3.8 allowed per game1-2 away

  • W5-1at Pittsburgh PiratesSep 23
  • L0-2at Pittsburgh PiratesSep 22
  • W5-3vs Washington NationalsSep 20
  • L1-9vs Washington NationalsSep 19
  • L5-6vs San Francisco GiantsSep 16
  • L3-10vs San Francisco GiantsSep 15
  • W2-1vs San Francisco GiantsSep 14
  • W3-1vs Chicago White SoxSep 13
  • W7-3vs Chicago White SoxSep 12
  • L1-2at San Francisco GiantsSep 9

Standings

TeamGames behindLostStreakWin %Won
Milwaukee-59W1.62799
Chicago1271L2.55187
Pittsburgh18.578W1.50981
St. Louis22.582L1.48477
Cincinnati2685L1.46273

How the scoring went

  1. 1st Inning1-0Burleson homered to right center (395 feet).
  2. 1st Inning1-1Lowe singled to left, Cruz scored.
  3. 8th Inning1-2Horwitz hit sacrifice fly to center, Simon scored.

Win probability

Above the line favours Pittsburgh Pirates, below favours St. Louis Cardinals.

Venue

  • PNC ParkPittsburgh, Pennsylvania
  • Attendance15822
  • OfficialsScott Barry, Tom Hanahan, Ron Kulpa, John Bacon

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.