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NFL · Final

Colts Edge Cardinals in Close Contest at Lucas Oil Stadium

Sunday, October 12, 2025, 1:00 PM ET · Lucas Oil Stadium

Indianapolis Colts 31, Arizona Cardinals 27, final. Our NFL picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Arizona Cardinals vs Indianapolis Colts?

Indianapolis Colts beat Arizona Cardinals 31-27 at Lucas Oil Stadium on October 12, 2025.

In a thrilling encounter at Lucas Oil Stadium, the Indianapolis Colts narrowly defeated the Arizona Cardinals with a final score of 31-27. This matchup was particularly significant as it showcased the Colts' strong home record, now standing at 6-1, while the Cardinals struggled on the road, dropping to 2-5.

The Colts entered the game with a solid recent form, having won four of their last five games, averaging 32.6 points scored and allowing just 17.8 points per game during that stretch. Their last outing resulted in a decisive 40-6 victory over the Las Vegas Raiders, further bolstering their confidence. In contrast, the Cardinals faced challenges in their recent performances, losing their last three games and averaging 20.6 points scored while allowing 19.2 points in their last five.

At home, the Colts have been particularly dominant, maintaining an undefeated home record of 5-0 this season. Their ability to score an average of 29.8 points while allowing 24.2 points per game at home has made them a formidable opponent. The Cardinals, on the other hand, have struggled away from home, with a record of 1-4 in their last five road games, which has contributed to their overall away record of 2-4.

The matchup also featured a number of key injuries that could have impacted both teams. For the Colts, A.J. Haulcy, Alec Pierce, Tyler Warren, and Josh Downs were all listed as questionable due to various injuries. Additionally, Coleman Owen was placed on injured reserve with a concussion. The Cardinals also faced injury concerns, with Jeremiyah Love and Will Johnson listed as questionable, while Zachary Carter and James Conner were on injured reserve.

In terms of betting, the market favored the Colts heavily, with a home win probability of 1.0, reflecting their strong performance and home advantage. The conditions at Lucas Oil Stadium were conducive to a high-energy game, with fans creating an electric atmosphere that undoubtedly fueled the Colts' performance.

Viewers were treated to a competitive game, with both teams displaying moments of brilliance. The Colts' offense was able to capitalize on their scoring opportunities, while the Cardinals fought hard to stay in the contest. The close scoreline reflects the intensity of the match and the resilience of both teams, making it a memorable fixture in the NFL season.

Injury report

  • A.J. HaulcyQuestionableAnkleIndianapolis Colts
  • Alec PierceQuestionableAnkleIndianapolis Colts
  • Tyler WarrenQuestionableGroinIndianapolis Colts
  • Josh DownsQuestionableCalfIndianapolis Colts
  • Coleman OwenInjured ReserveConcussionIndianapolis Colts
  • Jeremiyah LoveQuestionableAnkleArizona Cardinals
  • Zachary CarterInjured ReserveKneeArizona Cardinals
  • Will JohnsonQuestionableLower BodyArizona Cardinals
  • Tip ReimanOutAnkleArizona Cardinals
  • James ConnerInjured ReserveFootArizona Cardinals

Leaders

  • Passing yardsDaniel Jones22/30, 212 YDS, 2 TD, 1 INTIndianapolis Colts
  • Rushing yardsJonathan Taylor21 CAR, 123 YDS, 1 TDIndianapolis Colts
  • Receiving yardsTyler Warren6 REC, 63 YDS, 1 TDIndianapolis Colts
  • Passing yardsJacoby Brissett27/44, 320 YDS, 2 TD, 1 INTArizona Cardinals
  • Rushing yardsBam Knight11 CAR, 34 YDS, 1 TDArizona Cardinals
  • Receiving yardsZay Jones5 REC, 79 YDSArizona Cardinals

Recent form

Indianapolis Colts

Last 10: 7-3Streak W129.8 scored · 24.2 allowed per game5-0 at home

  • W40-6vs Las Vegas RaidersOct 5
  • L20-27at Los Angeles RamsSep 28
  • W41-20at Tennessee TitansSep 21
  • W29-28vs Denver BroncosSep 14
  • W33-8vs Miami DolphinsSep 7
  • W26-23vs Jacksonville JaguarsJan 5
  • L33-45at New York GiantsDec 29
  • W38-30vs Tennessee TitansDec 22
  • L13-31at Denver BroncosDec 15
  • W25-24at New England PatriotsDec 1

Arizona Cardinals

Last 10: 4-6Streak L323.7 scored · 21.6 allowed per game1-3 away

  • L21-22vs Tennessee TitansOct 5
  • L20-23vs Seattle SeahawksSep 26
  • L15-16at San Francisco 49ersSep 21
  • W27-22vs Carolina PanthersSep 14
  • W20-13at New Orleans SaintsSep 7
  • W47-24vs San Francisco 49ersJan 5
  • L9-13at Los Angeles RamsDec 29
  • L30-36at Carolina PanthersDec 22
  • W30-17vs New England PatriotsDec 15
  • L18-30vs Seattle SeahawksDec 8

Standings

TeamLostPoints againstPoints forTiedWin %WonOverall
Los Angeles0307401.00033-0
San Francisco148720.66722-1
Arizona31231080.25011-3
Seattle245321.16700-2-1
Jacksonville154600.66722-1
Tennessee153530.66722-1
Indianapolis272351.16700-2-1
Houston365400.00000-3

Box score

StatArizona CardinalsIndianapolis Colts
First downs2525
First downs passing1713
First downs rushing711
First downs by penalty11
Third downs9-144-8
Fourth downs0-10-0
Offensive plays7058
Total yards400355
Yards per play5.76.1
Drives1010
Net passing yards312205
Completions27/4422/30
Yards per pass6.86.6
Interceptions thrown11
Sacks allowed2-81-7
Rushing yards88150
Rushing attempts2427
Yards per rush3.75.6
Red zone trips3-64-4
Penalties7-655-40
Turnovers11
Fumbles lost00
Defensive touchdowns00
Time of possession32:0527:55

Win probability

Above the line favours Indianapolis Colts, below favours Arizona Cardinals.

Venue

  • Lucas Oil StadiumIndianapolis, IN
  • Attendance65523
  • OfficialsGreg Meyer, Tim Podraza, Jim Quirk, Shawn Hochuli, Patrick Holt, Jason Ledet, Larry Smith

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.