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NFL · 11/9 - 8:15 PM EST

Buffalo Bills vs Minnesota Vikings prediction & odds

Monday, November 9, 2026, 8:15 PM ET · U.S. Bank Stadium

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Quick answers

When and where is Buffalo Bills vs Minnesota Vikings?

Buffalo Bills visit Minnesota Vikings at U.S. Bank Stadium on November 9, 2026.

Who is favored in Buffalo Bills vs Minnesota Vikings?

Buffalo Bills are the favorite at DraftKings: moneyline -175, a price that implies about 64%. Minnesota Vikings are +145.

What are the spread and the over/under for Buffalo Bills vs Minnesota Vikings?

DraftKings has BUF -3.5, with the total at 45.5.

How are Buffalo Bills and Minnesota Vikings playing lately?

Minnesota Vikings are 9-1 in their last 10, Buffalo Bills 8-2.

The Minnesota Vikings will face the Buffalo Bills at U.S. Bank Stadium on November 10, 2026, in a matchup of two teams with identical 6-1 records. The Vikings, despite a recent loss to the Detroit Lions, have shown strong form with a home record of 5-0 this season. Their last five games include four wins, with notable performances from Kyler Murray, who has thrown for 1,022 yards and five touchdowns, and Justin Jefferson, leading the receiving corps with 335 yards and four touchdowns.

On the other side, the Bills are riding a three-game winning streak, most recently defeating the Baltimore Ravens 36-10. Quarterback Josh Allen has been a standout performer, amassing 1,793 passing yards and 11 touchdowns this season. Buffalo's offense has been potent, averaging 30.3 points over their last ten games.

Weather conditions are expected to be mild, with a temperature of 51°F and wind gusts up to 20 mph. The betting line from DraftKings currently favors the Bills by 3.5 points, with a total set at 45.5. Both teams are dealing with injuries, with several key players listed as questionable, including Vikings' Christian Darrisaw and Bills' Greg Gaines. This matchup promises to be a thrilling contest as both teams aim to solidify their positions in the playoff race.

Odds

BookSpreadTotalMoneyline
DraftKingsBUF -3.5 45.5 o -108 / u -112 Buffalo Bills -175 · Minnesota Vikings +145

What these prices pay on $100 · What these numbers mean

Injury report

  • Christian DarrisawQuestionableShoulderMinnesota Vikings
  • Kyler MurrayQuestionableHamstringMinnesota Vikings
  • Theo JacksonQuestionableQuadricepsMinnesota Vikings
  • Donovan JacksonInjured ReserveKnee - MeniscusMinnesota Vikings
  • Josh OliverInjured ReserveBicepsMinnesota Vikings
  • Greg GainesQuestionableCalfBuffalo Bills
  • Dee AlfordQuestionableAnkleBuffalo Bills
  • Spencer BrownQuestionableBackBuffalo Bills
  • DJ MooreQuestionableKneeBuffalo Bills
  • Joshua PalmerQuestionableHamstringBuffalo Bills

Leaders

  • Passing yardsKyler Murray100/154, 1,022 YDS, 5 TD, 3 INTMinnesota Vikings
  • Rushing yardsAaron Jones Sr.110 CAR, 458 YDS, 2 TDMinnesota Vikings
  • Receiving yardsJustin Jefferson28 REC, 335 YDS, 4 TDMinnesota Vikings
  • Passing yardsJosh Allen135/205, 1,793 YDS, 11 TD, 5 INTBuffalo Bills
  • Rushing yardsJames Cook III138 CAR, 707 YDS, 7 TDBuffalo Bills
  • Receiving yardsDalton Kincaid27 REC, 401 YDS, 2 TDBuffalo Bills

Recent form

Minnesota Vikings

Last 10: 9-1Streak L119.5 scored · 11.9 allowed per game5-0 at home

  • W23-16vs Tampa Bay BuccaneersSep 27
  • W15-10vs Miami DolphinsOct 4
  • W23-13vs New Orleans SaintsOct 11
  • W16-10vs Indianapolis ColtsOct 25
  • L19-15vs Detroit LionsNov 1

Buffalo Bills

Last 10: 8-2Streak W330.3 scored · 22.2 allowed per game4-0 away

  • W24-16vs Los Angeles ChargersSep 27
  • L29-26vs New England PatriotsOct 4
  • W37-34 OTvs Los Angeles RamsOct 12
  • W33-30vs Las Vegas RaidersOct 18
  • W36-10vs Baltimore RavensNov 1

Standings

TeamLostPoints againstPoints forTiedWin %WonOverall
Buffalo11812330.85766-1
New England31621840.62555-3
New York61881700.25022-6
Miami61811170.14311-6
Minnesota1931400.85766-1
Chicago21602140.75066-2
Detroit21802030.71455-2
Green Bay31641710.62555-3

Box score

StatBuffalo BillsMinnesota Vikings
Total points per game33.320.0
Yards per game404.6299.3
Passing yards per game256.1185.4
Rushing yards per game148.4113.9
Total points per game allowed25.913.3
Yards per game allowed366.4296.9
Passing yards per game allowed269.0180.1
Rushing yards per game allowed97.4116.7

Venue

  • U.S. Bank StadiumMinneapolis, MN

Elsewhere

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.