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MLB · Final

Cleveland Guardians Secure Victory Over Minnesota Twins

Friday, September 19, 2025, 8:10 PM ET · Target Field

Cleveland Guardians 6, Minnesota Twins 2, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Cleveland Guardians vs Minnesota Twins?

Cleveland Guardians beat Minnesota Twins 6-2 at Target Field on September 19, 2025.

The Cleveland Guardians triumphed over the Minnesota Twins with a final score of 6-2 at Target Field, marking a significant win in the ongoing series. This victory allowed the Guardians to clinch the series 4-2, further solidifying their position in the league as they continue to push for playoff contention.

Cleveland has been in remarkable form, boasting a record of 9-1 in their last ten games, including a seven-game winning streak. Their recent performances have seen them average 4.2 runs scored while allowing only 1.7 runs per game. In contrast, the Minnesota Twins have struggled, recording a 4-6 record over their last ten games, with an average of 5.6 runs scored and 6.3 runs allowed. The Twins are currently on a two-game losing streak, having lost their last two games against the New York Yankees prior to facing the Guardians.

At home, the Twins have a record of 2-3 in their last five games, while the Guardians have excelled on the road, winning all three of their recent away games. The Guardians' away record stands at 3-0 in their last three games, showcasing their ability to perform outside of their home venue. Historically, the Guardians have dominated the matchup against the Twins, with a head-to-head record of 14 wins, 6 losses, and 2 draws over the past two seasons.

In terms of injuries, the Twins are currently facing significant challenges with several key players sidelined. Byron Buxton is on the 10-Day Injured List due to a hip issue, Joe Ryan is on the 15-Day IL with a lower body injury, Austin Martin is also on the 10-Day IL with a hamstring problem, and both Mike Paredes and Mick Abel are on the 60-Day IL for oblique and elbow injuries, respectively. The Guardians are not without their own injury concerns, as Slade Cecconi is on the 15-Day IL with an arm issue, Rhys Hoskins is on the 10-Day IL with a back problem, and Shawn Armstrong is on the 60-Day IL due to a calf injury.

The scoring plays during the game highlighted Cleveland's offensive strength. In the first inning, Josh Naylor singled to right field, bringing in Steven Kwan and José Ramírez, which set the tone for the Guardians early on. The Twins managed to respond in the sixth inning when Lewis scored, tying the game at 2-2 after a wild pitch allowed Martin to score. However, the Guardians regained control in the eighth inning, with Naylor once again coming through with a single that scored Ramírez and Manzardo. In the ninth inning, Kwan and Martínez added to the tally, ensuring a comfortable lead for Cleveland.

The market had priced the Twins at a significant disadvantage, reflecting their recent form and the Guardians' strong performance. The odds indicated a home win probability of 0.0 for the Twins, underscoring the challenges they faced entering this matchup.

Weather conditions at Target Field were typical for a late September evening, with clear skies and mild temperatures, providing an ideal backdrop for baseball. Fans watching the game were treated to an exciting display of offensive prowess from the Guardians, along with a solid pitching performance that kept the Twins' scoring in check.

Overall, this game not only showcased the Guardians' ability to perform under pressure but also highlighted the struggles of the Twins as they navigate a difficult end to the season. With Cleveland's current form and the series victory, they remain a team to watch as the playoffs approach.

Injury report

  • Byron Buxton10-Day-ILHipMinnesota Twins
  • Joe Ryan15-Day-ILLower BodyMinnesota Twins
  • Austin Martin10-Day-ILHamstringMinnesota Twins
  • Mike Paredes60-Day-ILObliqueMinnesota Twins
  • Mick Abel60-Day-ILElbowMinnesota Twins
  • Slade Cecconi15-Day-ILArmCleveland Guardians
  • Rhys Hoskins10-Day-ILBackCleveland Guardians
  • Shawn Armstrong60-Day-ILCalfCleveland Guardians

Recent form

Minnesota Twins

Last 10: 4-6Streak L25.6 scored · 6.3 allowed per game2-3 at home

  • L5-10vs New York YankeesSep 17
  • L9-10vs New York YankeesSep 16
  • W7-0vs New York YankeesSep 15
  • L4-6vs Arizona DiamondbacksSep 14
  • W9-8vs Arizona DiamondbacksSep 13
  • L2-12at Los Angeles AngelsSep 10
  • W12-3at Los Angeles AngelsSep 9
  • W5-1at Kansas City RoyalsSep 7
  • L2-11at Kansas City RoyalsSep 6
  • L1-2at Kansas City RoyalsSep 5

Cleveland Guardians

Last 10: 9-1Streak W74.2 scored · 1.7 allowed per game3-0 away

  • W3-1at Detroit TigersSep 18
  • W4-0at Detroit TigersSep 17
  • W7-5at Detroit TigersSep 16
  • W3-2vs Chicago White SoxSep 14
  • W3-1vs Chicago White SoxSep 13
  • W4-0vs Chicago White SoxSep 12
  • W3-2vs Kansas City RoyalsSep 11
  • L3-4vs Kansas City RoyalsSep 10
  • W2-0vs Kansas City RoyalsSep 9
  • W10-2vs Kansas City RoyalsSep 8

Standings

TeamGames behindLostStreakWin %Won
Chicago-66L1.52573
Cleveland369L1.50470
Minnesota6.573L1.47967
Detroit975W1.46064
Kansas City11.578L3.44362

How the scoring went

  1. 1st Inning2-0Naylor singled to right, Kwan scored and Ramírez scored.
  2. 6th Inning2-1Martin scored on Messick wild pitch, Keaschall to third on wild pitch by Messick.
  3. 6th Inning2-1Martin scored on Messick wild pitch, Keaschall to third on wild pitch by Messick.
  4. 6th Inning2-2Lewis singled to center, Keaschall scored.
  5. 8th Inning4-2Naylor singled to right, Ramírez scored and Manzardo scored.
  6. 9th Inning5-2Kwan doubled to left, Fry scored.
  7. 9th Inning6-2Martínez doubled to right, Kwan scored.

Win probability

Above the line favours Minnesota Twins, below favours Cleveland Guardians.

Venue

  • Target FieldMinneapolis, Minnesota
  • Attendance20159
  • OfficialsVic Carapazza, Mark Ripperger, Jacob Metz, Nick Mahrley

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.