49ers Defeat Broncos 24-14 at Levi's Stadium
Sunday, October 4, 2026, 4:25 PM ET · Levi's Stadium
San Francisco 49ers 24, Denver Broncos 14, final. Our NFL picks are sealed as a hash before kickoff and settled in public, losses included.
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Quick answers
Who won Denver Broncos vs San Francisco 49ers?
San Francisco 49ers beat Denver Broncos 24-14 at Levi's Stadium on October 4, 2026.
Who was favored in Denver Broncos vs San Francisco 49ers?
San Francisco 49ers were the favorite at DraftKings, moneyline -166 (about 62% implied). The favorite won.
The San Francisco 49ers secured a decisive 24-14 victory over the Denver Broncos at Levi's Stadium, maintaining their perfect home record of 5-0 this season. This matchup was significant as it showcased the 49ers' dominance at home and their ability to continue their winning streak, now at three games. The 49ers improved their overall record to 5-1, while the Broncos fell to 2-3.
In the lead-up to the game, the 49ers had an impressive home record of 4-0, having averaged 31.5 points scored while allowing 19.1 points per game in their last ten outings. Their recent form included victories against the Arizona Cardinals (36-30), Miami Dolphins (35-13), and Los Angeles Rams (27-7). In contrast, the Broncos, with a 2-2 away record, had averaged 22.6 points scored and allowed 20.8 points in their last ten games. They entered the game on a two-game winning streak, having defeated the Los Angeles Rams (30-26) and Jacksonville Jaguars (20-13).
Historically, the 49ers have performed well at home against the Broncos, and this game continued that trend. The 49ers were without key players, including Kyle Juszczyk, Jordan James, James Thompson Jr., Ephesians Prysock, and Kurtis Rourke, all listed as out due to various injuries or coach's decisions. The Broncos also faced challenges with injuries, as Pat Surtain II, Riley Moss, Dondrea Tillman, and others were out, while Pat Bryant was listed as questionable with an ankle injury.
The betting market, as provided by DraftKings, had the 49ers favored by a spread of -3.0, with a total set at 48.5. The moneyline showed the 49ers at -166 and the Broncos at +140, indicating a clear expectation of a 49ers victory.
Conditions at Levi's Stadium were optimal for football, contributing to a competitive atmosphere. Fans witnessed a game that highlighted the 49ers' offensive capabilities and defensive resilience. The 49ers' ability to score 24 points while limiting the Broncos to 14 demonstrated their strength, particularly at home.
Viewers were treated to a display of strong offensive plays from the 49ers, showcasing their scoring prowess, while the Broncos struggled to keep pace. The game underscored the 49ers' home-field advantage and their ability to capitalize on the Broncos' defensive weaknesses. Overall, the matchup was a testament to the 49ers' current form and their position as a formidable team in the league.
What we said beforehand
The upcoming NFL matchup between the San Francisco 49ers and the Denver Broncos at Levi's Stadium promises to be an intriguing contest, particularly as the 49ers enter the game with an impressive home record of 3-0 this season. The 49ers have been dominant, winning their last five games and showcasing a strong offensive performance, as evidenced by their scoring average of 31.5 points per game at home. In contrast, the Broncos, with a 2-1 record on the road, will look to build on their recent success after winning two straight games.
The 49ers have been on a winning streak, having secured victories against the Los Angeles Chargers (41-17), Las Vegas Raiders (18-12), Los Angeles Rams (27-7), Miami Dolphins (35-13), and Arizona Cardinals (36-30). Their last five games reflect a powerful offense, led by quarterback Brock Purdy, who has thrown for 789 yards, 9 touchdowns, and 1 interception this season. Running back Christian McCaffrey has also been a key contributor, rushing for 166 yards and 3 touchdowns on 35 carries.
On the other side, the Denver Broncos have had a mixed bag of results recently. After suffering a loss to the Green Bay Packers (33-13) and the Kansas City Chiefs (31-10), they bounced back with wins against the Minnesota Vikings (34-6), Jacksonville Jaguars (20-13), and Los Angeles Rams (30-26). The Broncos have averaged 22.6 points per game on the road, with quarterback Bo Nix passing for 605 yards, 4 touchdowns, and 3 interceptions this season. Running back J.K. Dobbins has also provided a solid ground game with 121 rushing yards.
Historically, the 49ers have had a strong home advantage, going 9-1 in their last ten games at Levi's Stadium. Their home scoring average of 31.5 points per game is complemented by a solid defense that allows just 19.1 points per game. The Broncos, while performing well at home with a record of 5-1, have shown some vulnerability on the road, where they have a record of 3-1.
In terms of injuries, the 49ers will be missing several key players, including Jordan James, James Thompson Jr., Ephesians Prysock, Kurtis Rourke, and Enrique Cruz Jr., all ruled out due to coach's decisions or injuries. The Broncos will also be without Dallen Bentley, Dondrea Tillman (hamstring), Tyler Onyedim, Kage Casey, and Sam Ehlinger, all ruled out for the game.
The betting market reflects the 49ers as the favorites, with DraftKings setting the odds at San Francisco -3, a total of 48.5 for the game, and home moneyline odds of -166 compared to the Broncos' +140. Weather conditions are expected to be warm, with a temperature of 91°F, clear skies, and light winds gusting at 8 mph, which should not significantly impact gameplay.
As fans prepare for this matchup, they should watch for the 49ers' potent offense, particularly how Brock Purdy and Christian McCaffrey perform against the Broncos' defense. Additionally, the effectiveness of the Broncos' passing game, led by Bo Nix, will be crucial as they look to exploit any weaknesses in the 49ers' defense. With both teams entering the game with different momentum, this contest at Levi's Stadium is set to be a compelling clash.
Odds
| Book | Spread | Total | Moneyline |
|---|---|---|---|
| DraftKings | SF -3 | 48.5 o -105 / u -115 | Denver Broncos +140 · San Francisco 49ers -166 |
Injury report
- Kyle JuszczykOutKneeSan Francisco 49ers
- Jordan JamesOutCoach's DecisionSan Francisco 49ers
- James Thompson Jr.OutAnkleSan Francisco 49ers
- Ephesians PrysockOutCoach's DecisionSan Francisco 49ers
- Kurtis RourkeOutCoach's DecisionSan Francisco 49ers
- Pat BryantQuestionableAnkleDenver Broncos
- Riley MossOutRibsDenver Broncos
- Pat Surtain IIOutAnkleDenver Broncos
- Dallen BentleyOutCoach's DecisionDenver Broncos
- Dondrea TillmanOutHamstringDenver Broncos
Leaders
- Passing yardsBrock Purdy19/30, 218 YDS, 2 TDSan Francisco 49ers
- Rushing yardsChristian McCaffrey15 CAR, 52 YDS, 1 TDSan Francisco 49ers
- Receiving yardsMike Evans5 REC, 76 YDSSan Francisco 49ers
- Passing yardsBo Nix25/42, 214 YDS, 1 TDDenver Broncos
- Rushing yardsJ.K. Dobbins11 CAR, 40 YDSDenver Broncos
- Receiving yardsRJ Harvey10 REC, 68 YDSDenver Broncos
Recent form
San Francisco 49ers
Last 10: 9-1Streak W331.5 scored · 19.1 allowed per game5-1 at home
- W36-30vs Arizona CardinalsSep 27
- W35-13vs Miami DolphinsSep 20
- W27-7at Los Angeles RamsSep 11
- L3-13vs Seattle SeahawksJan 4
- W42-38vs Chicago BearsDec 29
- W48-27at Indianapolis ColtsDec 23
- W37-24vs Tennessee TitansDec 14
- W26-8at Cleveland BrownsNov 30
- W20-9vs Carolina PanthersNov 25
- W41-22at Arizona CardinalsNov 16
Denver Broncos
Last 10: 8-2Streak W222.6 scored · 20.8 allowed per game3-1 away
- W30-26vs Los Angeles RamsSep 28
- W20-13vs Jacksonville JaguarsSep 20
- L10-31at Kansas City ChiefsSep 15
- W19-3vs Los Angeles ChargersJan 4
- W20-13at Kansas City ChiefsDec 26
- L20-34vs Jacksonville JaguarsDec 21
- W34-26vs Green Bay PackersDec 14
- W24-17at Las Vegas RaidersDec 7
- W27-26at Washington CommandersDec 1
- W22-19vs Kansas City ChiefsNov 16
Standings
| Team | Lost | Points against | Points for | Tied | Win % | Won | Overall |
|---|---|---|---|---|---|---|---|
| Kansas City | 0 | 77 | 118 | 0 | 1.000 | 4 | 4-0 |
| Las Vegas | 1 | 84 | 115 | 0 | .750 | 3 | 3-1 |
| Denver | 2 | 94 | 74 | 0 | .500 | 2 | 2-2 |
| Los Angeles | 4 | 106 | 67 | 0 | .000 | 0 | 0-4 |
| San Francisco | 0 | 64 | 122 | 0 | 1.000 | 4 | 4-0 |
| Seattle | 1 | 73 | 105 | 0 | .750 | 3 | 3-1 |
| Los Angeles | 2 | 83 | 85 | 0 | .500 | 2 | 2-2 |
| Arizona | 3 | 117 | 87 | 0 | .250 | 1 | 1-3 |
Box score
| Stat | Denver Broncos | San Francisco 49ers |
|---|---|---|
| First downs | 16 | 20 |
| First downs passing | 10 | 8 |
| First downs rushing | 6 | 11 |
| First downs by penalty | 0 | 1 |
| Third downs | 8-17 | 6-13 |
| Fourth downs | 1-1 | 1-2 |
| Offensive plays | 64 | 65 |
| Total yards | 296 | 358 |
| Yards per play | 4.6 | 5.5 |
| Drives | 9 | 11 |
| Net passing yards | 214 | 218 |
| Completions | 25/42 | 19/30 |
| Yards per pass | 5.1 | 7.3 |
| Interceptions thrown | 0 | 0 |
| Sacks allowed | 0-0 | 0-0 |
| Rushing yards | 82 | 140 |
| Rushing attempts | 22 | 35 |
| Yards per rush | 3.7 | 4.0 |
| Red zone trips | 1-1 | 2-3 |
| Penalties | 7-44 | 1-5 |
| Turnovers | 1 | 0 |
| Fumbles lost | 1 | 0 |
| Defensive touchdowns | 0 | 0 |
| Time of possession | 30:53 | 29:07 |
Win probability
Above the line favours San Francisco 49ers, below favours Denver Broncos.
Venue
- Levi's StadiumSanta Clara, CA
- Attendance70776
- OfficialsBarry Anderson, Ronald Torbert, Keith Washington, Ryan Dickson, Tripp Sutter, Brett Bergman, Courtney Brown
Elsewhere
- Fantasy football: Lamb, Walker among leading scorers through Sunday's 4 p.m. ET games
- Wild stats from NFL Week 4 featuring Cowboys, Bears, Eagles, Seahawks, more
- Brock Purdy throws 2 TD passes to lead the undefeated 49ers past the Broncos 24-14
- Week 4 NFL highlights: Best plays, moments, touchdowns, more
- Unbeaten Vikings keep Dolphins winless with dominant defense, Reichard's kicks, Hockenson's catches
- Miami Dolphins vs. Minnesota Vikings: Game Highlights