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NFL · Final

Jaguars Dominate Colts in Convincing Victory

Sunday, November 1, 2026, 1:00 PM ET · EverBank Stadium

Jacksonville Jaguars 42, Indianapolis Colts 7, final. Our NFL picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Indianapolis Colts vs Jacksonville Jaguars?

Jacksonville Jaguars beat Indianapolis Colts 42-7 at EverBank Stadium on November 1, 2026.

Who was favored in Indianapolis Colts vs Jacksonville Jaguars?

Jacksonville Jaguars were the favorite at DraftKings, moneyline -500 (about 83% implied). The favorite won.

The Jacksonville Jaguars delivered a resounding performance against the Indianapolis Colts, securing a decisive 42-7 victory at EverBank Stadium. This matchup showcased the Jaguars' strong home advantage, improving their home record to 6-1 this season. The Colts, in stark contrast, fell to 2-7, continuing their struggles on the road.

The Jaguars entered the game with a solid home record of 5-1, having averaged 30.0 points scored per game while allowing only 16.8. Despite a recent loss to the Houston Texans, the Jaguars had previously shown resilience, winning eight of their last ten games. Their last five games reflected a record of 3-2, with an average of 24.0 points scored and 18.8 allowed. The Colts, however, were on a three-game losing streak and had only managed to win two of their last ten games. Their away record stood at 1-4, with an average of 22.8 points scored and a concerning 28.9 points allowed per game.

In terms of previous meetings, the Jaguars had dominated the Colts in their last two encounters, winning both matchups in the 2025 season. The most recent meeting before this game was on December 28, 2025, where the Jaguars won 23-17, and they also claimed a 36-19 victory earlier that month.

Injuries played a role in the game, with several key players listed as questionable for the Jaguars, including Travon Walker, DaVon Hamilton, Ezra Cleveland, and Eric Murray. The Colts were missing Riley Leonard, Bryce Boettcher, Justin Walley, Kevin Givens, and Anthony Gould, all of whom were ruled out.

The betting market reflected the Jaguars' dominance, with DraftKings setting the spread at -10.5 in favor of Jacksonville. The total for the game was set at 45.5, with both the over and under priced at -110. The Jaguars were heavily favored with a moneyline of -500, while the Colts were listed at +380.

Conditions for the game were favorable, contributing to the Jaguars' strong performance. Fans watching the game were treated to a display of offensive prowess from the Jaguars, who capitalized on the Colts' defensive vulnerabilities. The Jaguars' ability to score efficiently and limit the Colts' offensive output was evident throughout the contest, culminating in a commanding victory.

What we said beforehand

The Jacksonville Jaguars will host the Indianapolis Colts at EverBank Stadium on November 1, 2026, in a matchup that carries significant implications for both teams in the AFC South. The Jaguars enter the game with a strong home record of 4-2, while the Colts are struggling with a 2-5 record overall. This game is particularly noteworthy as the Jaguars have won both of their previous meetings against the Colts in the 2025 season, including a 36-19 victory at home and a 23-17 win on the road.

In their last five games, the Jaguars have a record of 3-2, scoring an average of 24.0 points while allowing 18.8 points per game. Their most recent outing ended in a narrow loss to the Houston Texans, with a score of 34-31. Prior to that, they secured victories against the New England Patriots (35-6), Cincinnati Bengals (22-17), and Philadelphia Eagles (19-17). The Colts, on the other hand, have lost three consecutive games, bringing their record in the last five to 2-3, with an average of 20.2 points scored and 21.2 points allowed. Their last game resulted in a 16-10 loss to the Minnesota Vikings.

At home, the Jaguars have been particularly effective, boasting a home record of 5-1 this season. They have averaged 30.0 points scored and allowed only 16.8 points per game over their last ten home outings. In contrast, the Colts have struggled on the road, with an away record of 1-4 this season, averaging 22.8 points scored and 28.9 points allowed in their last ten games.

In terms of injuries, the Jaguars will be missing several players, including CJ Williams, Wesley Williams, Albert Regis, Jamal Hill, and Alijah Huzzie, all ruled out due to coach's decisions. The Colts will also be without Riley Leonard, Bryce Boettcher (groin), Justin Walley (knee), Kevin Givens, and Anthony Gould (concussion), which could impact their performance.

The betting market reflects the Jaguars' strong position, with DraftKings listing them as 10-point favorites. The total for the game is set at 45.5, with both the over and under priced at -110.

Weather conditions are expected to be mild, with a temperature of 76°F, a 71% chance of precipitation, and gusts of up to 24 mph, which could influence gameplay.

As the game approaches, viewers should watch for the performance of Jaguars quarterback Trevor Lawrence, who has thrown for 1,480 yards with 14 touchdowns and 4 interceptions this season. Additionally, the effectiveness of Colts quarterback Daniel Jones, who has 1,398 passing yards with 4 touchdowns and 7 interceptions, will be crucial in determining the outcome. The rushing game will also be significant, with Jaguars' Bhayshul Tuten and Colts' Jonathan Taylor both key players in their respective offenses.

Odds

BookSpreadTotalMoneyline
DraftKingsJAX -10.5 45.5 o -110 / u -110 Indianapolis Colts +380 · Jacksonville Jaguars -500

What these prices pay on $100 · What these numbers mean

Injury report

  • Travon WalkerQuestionableRibsJacksonville Jaguars
  • DaVon HamiltonQuestionableKneeJacksonville Jaguars
  • Ezra ClevelandQuestionableAnkleJacksonville Jaguars
  • Eric MurrayQuestionableElbowJacksonville Jaguars
  • CJ WilliamsOutCoach's DecisionJacksonville Jaguars
  • Riley LeonardOutCoach's DecisionIndianapolis Colts
  • Bryce BoettcherOutGroinIndianapolis Colts
  • Justin WalleyOutKneeIndianapolis Colts
  • Kevin GivensOutCoach's DecisionIndianapolis Colts
  • Anthony GouldOutConcussionIndianapolis Colts

Leaders

  • Passing yardsTrevor Lawrence10/14, 210 YDS, 3 TDJacksonville Jaguars
  • Rushing yardsBhayshul Tuten16 CAR, 104 YDS, 1 TDJacksonville Jaguars
  • Receiving yardsBhayshul Tuten2 REC, 55 YDS, 1 TDJacksonville Jaguars
  • Passing yardsDaniel Jones19/28, 144 YDS, 1 TD, 2 INTIndianapolis Colts
  • Rushing yardsDJ Giddens6 CAR, 43 YDSIndianapolis Colts
  • Receiving yardsKeenan Allen7 REC, 67 YDSIndianapolis Colts

Recent form

Jacksonville Jaguars

Last 10: 8-2Streak L130 scored · 16.8 allowed per game5-1 at home

  • L31-34vs Houston TexansOct 18
  • W19-17vs Philadelphia EaglesOct 11
  • W22-17at Cincinnati BengalsOct 4
  • W35-6vs New England PatriotsSep 27
  • L13-20at Denver BroncosSep 20
  • W34-10vs Cleveland BrownsSep 13
  • W41-7vs Tennessee TitansJan 4
  • W23-17at Indianapolis ColtsDec 28
  • W34-20at Denver BroncosDec 21
  • W48-20vs New York JetsDec 14

Indianapolis Colts

Last 10: 2-8Streak L322.8 scored · 28.9 allowed per game1-4 away

  • L10-16at Minnesota VikingsOct 25
  • L20-26vs Tennessee TitansOct 18
  • L22-34at Pittsburgh SteelersOct 11
  • W30-13at Washington CommandersOct 4
  • W19-17vs Houston TexansSep 27
  • L30-33at Kansas City ChiefsSep 21
  • L23-41vs Baltimore RavensSep 13
  • L30-38at Houston TexansJan 4
  • L17-23vs Jacksonville JaguarsDec 28
  • L27-48vs San Francisco 49ersDec 23

Standings

TeamLostPoints againstPoints forTiedWin %WonOverall
Jacksonville21111960.71455-2
Houston51701650.28622-5
Indianapolis62221610.25022-6
Tennessee61561080.14311-6

Box score

StatIndianapolis ColtsJacksonville Jaguars
First downs1718
First downs passing99
First downs rushing67
First downs by penalty22
Third downs3-116-12
Fourth downs0-20-0
Offensive plays6053
Total yards243366
Yards per play4.06.9
Drives1412
Net passing yards134183
Completions21/3011/17
Yards per pass3.99.2
Interceptions thrown20
Sacks allowed4-183-35
Rushing yards109183
Rushing attempts2633
Yards per rush4.25.5
Red zone trips1-21-1
Penalties9-548-65
Turnovers31
Fumbles lost11
Defensive touchdowns01
Time of possession30:2229:38

Win probability

Above the line favours Jacksonville Jaguars, below favours Indianapolis Colts.

Venue

  • EverBank StadiumJacksonville, FL
  • OfficialsTrawick Boger, Adrian Hill, Greg Steed, Roy Ellison, Julian Mapp, Danny Short, Glen Fucik

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.