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NFL · Final

Colts Dominate Titans in NFL Showdown

Sunday, September 21, 2025, 1:00 PM ET · Nissan Stadium

Indianapolis Colts 41, Tennessee Titans 20, final. Our NFL picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Indianapolis Colts vs Tennessee Titans?

Indianapolis Colts beat Tennessee Titans 41-20 at Nissan Stadium on September 21, 2025.

In a decisive clash at Nissan Stadium, the Indianapolis Colts triumphed over the Tennessee Titans with a final score of 41-20. This victory further highlighted the contrasting fortunes of the two teams, with the Colts maintaining their perfect away record at 3-0, while the Titans fell to 0-3 at home this season.

The Titans have struggled significantly, now on an eight-game losing streak that dates back to last season, with their last victory occurring on November 24, 2024, against the Houston Texans. In their last ten games, they have managed only one win, with an average of 18.5 points scored per game, while allowing an average of 27.3 points. Their most recent performance against the Los Angeles Rams ended in a 19-33 defeat, further emphasizing their ongoing difficulties.

Conversely, the Colts have found success, winning six of their last ten games and currently riding a three-game winning streak. They have averaged 25.1 points per game during this stretch, while allowing 27.0 points. Their latest victory came against the Denver Broncos, where they secured a narrow 29-28 win. The Colts have also shown resilience on the road, boasting a 2-2 record away from home.

Historically, the Titans have struggled against the Colts, losing both of their previous meetings in the 2024 season. The most recent encounter on December 22, 2024, saw the Titans fall 30-38 in Indianapolis, and earlier that season, they lost 17-20 at home. This ongoing trend of defeat has placed additional pressure on the Titans as they seek to turn their season around.

In terms of injuries, the Titans are dealing with several key players on the injury report. Carnell Tate and Andre James are both listed as questionable, while Kendell Brooks, Tanoh Kpassagnon, and Dorian Mausi are on Injured Reserve. The Colts also have concerns, with A.J. Haulcy, Alec Pierce, Tyler Warren, and Josh Downs all marked as questionable, while Coleman Owen is on Injured Reserve due to a concussion.

The betting market reflected the Colts' strong form, pricing them as significant favorites with a home win probability for the Titans at 0.0, indicating a lack of confidence in their ability to secure a victory. Conditions for the game were typical for a late September afternoon, with no specific weather-related issues reported.

Viewers should have noted the Colts' offensive efficiency, particularly their ability to score consistently, as well as the Titans' defensive struggles that allowed for a high-scoring game. The Colts' recent form and the Titans' ongoing woes made this matchup particularly compelling, showcasing the challenges faced by the home team as they continue to search for answers in a difficult season.

Injury report

  • Carnell TateQuestionableUndisclosedTennessee Titans
  • Kendell BrooksInjured ReserveUndisclosedTennessee Titans
  • Andre JamesQuestionableUndisclosedTennessee Titans
  • Tanoh KpassagnonInjured ReserveUndisclosedTennessee Titans
  • Dorian MausiInjured ReserveUndisclosedTennessee Titans
  • A.J. HaulcyQuestionableAnkleIndianapolis Colts
  • Alec PierceQuestionableAnkleIndianapolis Colts
  • Tyler WarrenQuestionableGroinIndianapolis Colts
  • Josh DownsQuestionableCalfIndianapolis Colts
  • Coleman OwenInjured ReserveConcussionIndianapolis Colts

Leaders

  • Passing yardsCam Ward23/38, 219 YDS, 1 TD, 1 INTTennessee Titans
  • Rushing yardsTony Pollard16 CAR, 45 YDS, 1 TDTennessee Titans
  • Receiving yardsChig Okonkwo5 REC, 66 YDSTennessee Titans
  • Passing yardsDaniel Jones18/25, 228 YDS, 1 TDIndianapolis Colts
  • Rushing yardsJonathan Taylor17 CAR, 102 YDS, 3 TDIndianapolis Colts
  • Receiving yardsMichael Pittman Jr.6 REC, 73 YDS, 1 TDIndianapolis Colts

Recent form

Tennessee Titans

Last 10: 1-9Streak L818.5 scored · 27.3 allowed per game0-5 at home

  • L19-33vs Los Angeles RamsSep 14
  • L12-20at Denver BroncosSep 7
  • L14-23vs Houston TexansJan 5
  • L13-20at Jacksonville JaguarsDec 29
  • L30-38at Indianapolis ColtsDec 22
  • L27-37vs Cincinnati BengalsDec 15
  • L6-10vs Jacksonville JaguarsDec 8
  • L19-42at Washington CommandersDec 1
  • W32-27at Houston TexansNov 24
  • L13-23vs Minnesota VikingsNov 17

Indianapolis Colts

Last 10: 6-4Streak W325.1 scored · 27 allowed per game2-2 away

  • W29-28vs Denver BroncosSep 14
  • W33-8vs Miami DolphinsSep 7
  • W26-23vs Jacksonville JaguarsJan 5
  • L33-45at New York GiantsDec 29
  • W38-30vs Tennessee TitansDec 22
  • L13-31at Denver BroncosDec 15
  • W25-24at New England PatriotsDec 1
  • L6-24vs Detroit LionsNov 24
  • W28-27at New York JetsNov 17
  • L20-30vs Buffalo BillsNov 10

Standings

TeamLostPoints againstPoints forTiedWin %WonOverall
Jacksonville154600.66722-1
Tennessee153530.66722-1
Indianapolis272351.16700-2-1
Houston365400.00000-3

Box score

StatIndianapolis ColtsTennessee Titans
First downs2221
First downs passing1011
First downs rushing98
First downs by penalty32
Third downs2-85-14
Fourth downs2-21-2
Offensive plays5365
Total yards365282
Yards per play6.94.3
Drives99
Net passing yards228196
Completions18/2523/38
Yards per pass9.14.7
Interceptions thrown01
Sacks allowed0-04-23
Rushing yards13786
Rushing attempts2823
Yards per rush4.93.7
Red zone trips2-42-2
Penalties4-238-68
Turnovers01
Fumbles lost00
Defensive touchdowns10
Time of possession28:4131:19

Win probability

Above the line favours Tennessee Titans, below favours Indianapolis Colts.

Venue

  • Nissan StadiumNashville, TN
  • Attendance56361
  • OfficialsTerry Brown, Scott Novak, Tony Josselyn, Mark Stewart, Don Willard, Brandon Cruse, Brian Sakowski

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.