Las Vegas Raiders vs San Francisco 49ers prediction & odds
Sunday, November 8, 2026, 4:25 PM ET · Levi's Stadium
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Quick answers
When and where is Las Vegas Raiders vs San Francisco 49ers?
Las Vegas Raiders visit San Francisco 49ers at Levi's Stadium on November 8, 2026.
Who is favored in Las Vegas Raiders vs San Francisco 49ers?
San Francisco 49ers are the favorite at DraftKings: moneyline -535, a price that implies about 84%. Las Vegas Raiders are +400.
What are the spread and the over/under for Las Vegas Raiders vs San Francisco 49ers?
DraftKings has SF -10, with the total at 52.5.
How are Las Vegas Raiders and San Francisco 49ers playing lately?
San Francisco 49ers are 8-2 in their last 10, Las Vegas Raiders 5-5.
The San Francisco 49ers, boasting a strong home record of 6-1, will face the Las Vegas Raiders, who sit at 4-4, in an intriguing matchup at Levi's Stadium on November 8, 2026. The 49ers are coming off a loss to the Atlanta Falcons, ending a four-game winning streak. Meanwhile, the Raiders recently snapped a four-game losing streak with a victory over the New York Jets. San Francisco's offense is led by quarterback Brock Purdy, who has thrown for 1,748 yards, with 15 touchdowns and 4 interceptions this season. Running back Christian McCaffrey has also been a key player, accumulating 389 rushing yards and 8 touchdowns. The Raiders will look to Kirk Cousins, who has 2,124 passing yards and 19 touchdowns, to lead their offense. Weather conditions are expected to be favorable, with a temperature of 73°F and no precipitation. The betting odds from DraftKings currently favor the 49ers by 10 points, with a total set at 52.5. Both teams will be dealing with injuries, as the 49ers have several players listed as questionable, including Marques Sigle and Garret Wallow, while the Raiders have Patrick Johnson on injured reserve. This game promises to be a crucial test for both teams as they aim to solidify their playoff positions.
Odds
| Book | Spread | Total | Moneyline |
|---|---|---|---|
| DraftKings | SF -10 | 52.5 o -112 / u -108 | Las Vegas Raiders +400 · San Francisco 49ers -535 |
Injury report
- De'Zhaun StriblingInjured ReserveAnkleSan Francisco 49ers
- Brandon AiyukOutPersonalSan Francisco 49ers
- Marques SigleQuestionableAnkleSan Francisco 49ers
- Garret WallowQuestionableHamstringSan Francisco 49ers
- Luke GiffordQuestionableGroinSan Francisco 49ers
- Darien PorterQuestionableGroinLas Vegas Raiders
- Patrick JohnsonInjured ReserveNeckLas Vegas Raiders
- Carter RunyonInjured ReserveFootLas Vegas Raiders
- Keyron CrawfordInjured ReserveAnkleLas Vegas Raiders
- Chigozie AnusiemInjured ReserveKneeLas Vegas Raiders
Leaders
- Passing yardsBrock Purdy146/211, 1,748 YDS, 15 TD, 4 INTSan Francisco 49ers
- Rushing yardsChristian McCaffrey84 CAR, 389 YDS, 8 TDSan Francisco 49ers
- Receiving yardsGeorge Kittle34 REC, 425 YDS, 5 TDSan Francisco 49ers
- Passing yardsKirk Cousins180/283, 2,124 YDS, 19 TD, 5 INTLas Vegas Raiders
- Rushing yardsAshton Jeanty108 CAR, 337 YDS, 1 TDLas Vegas Raiders
- Receiving yardsBrock Bowers41 REC, 547 YDS, 5 TDLas Vegas Raiders
Recent form
San Francisco 49ers
Last 10: 8-2Streak L129 scored · 21.7 allowed per game5-1 at home
- W36-30vs Arizona CardinalsSep 27
- W24-14vs Denver BroncosOct 4
- W32-29vs Seattle SeahawksOct 11
- W23-17vs Washington CommandersOct 19
- L29-20vs Atlanta FalconsOct 25
Las Vegas Raiders
Last 10: 5-5Streak W124.5 scored · 27.6 allowed per game3-1 away
- L30-27vs Kansas City ChiefsOct 4
- L45-17vs New England PatriotsOct 11
- L33-30vs Buffalo BillsOct 18
- L35-21vs Los Angeles RamsOct 25
- W38-33vs New York JetsNov 1
Standings
| Team | Lost | Points against | Points for | Tied | Win % | Won | Overall |
|---|---|---|---|---|---|---|---|
| Denver | 2 | 165 | 172 | 0 | .750 | 6 | 6-2 |
| Kansas City | 2 | 131 | 167 | 0 | .714 | 5 | 5-2 |
| Las Vegas | 4 | 230 | 221 | 0 | .500 | 4 | 4-4 |
| Los Angeles | 7 | 175 | 99 | 0 | .000 | 0 | 0-7 |
| San Francisco | 1 | 139 | 197 | 0 | .857 | 6 | 6-1 |
| Seattle | 4 | 159 | 185 | 0 | .500 | 4 | 4-4 |
| Los Angeles | 4 | 168 | 194 | 0 | .500 | 4 | 4-4 |
| Arizona | 5 | 238 | 175 | 0 | .375 | 3 | 3-5 |
Box score
| Stat | Las Vegas Raiders | San Francisco 49ers |
|---|---|---|
| Total points per game | 27.6 | 28.1 |
| Yards per game | 350.4 | 377.1 |
| Passing yards per game | 273.1 | 249.7 |
| Rushing yards per game | 77.3 | 127.4 |
| Total points per game allowed | 28.8 | 19.9 |
| Yards per game allowed | 397.1 | 312.9 |
| Passing yards per game allowed | 250.8 | 223.9 |
| Rushing yards per game allowed | 146.4 | 89.0 |
Venue
- Levi's StadiumSanta Clara, CA
Elsewhere
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