Rams Dominate Cardinals in Convincing Victory
Sunday, December 7, 2025, 4:25 PM ET · State Farm Stadium
Los Angeles Rams 45, Arizona Cardinals 17, final. Our NFL picks are sealed as a hash before kickoff and settled in public, losses included.
The next free pick, for your email
Team, bet, price and the hash it was sealed under, on this page the moment you send. Lose or win, it stays public.
or by email
Public record of the main pick, losses included: 115 won, 44 lost. See every pick
One free pick a day by email until you unsubscribe, in one click. 21+.
Quick answers
Who won Los Angeles Rams vs Arizona Cardinals?
Los Angeles Rams beat Arizona Cardinals 45-17 at State Farm Stadium on December 7, 2025.
Who was favored in Los Angeles Rams vs Arizona Cardinals?
Los Angeles Rams were the favorite at DraftKings, moneyline -485 (about 83% implied). The favorite won.
The Los Angeles Rams delivered a commanding performance against the Arizona Cardinals, winning decisively with a final score of 45-17. This matchup highlighted the stark contrast in the teams' recent forms, with the Rams entering the game with a record of 10-3, while the Cardinals struggled at 3-10.
The Rams had been performing well, boasting a record of 7-3 over their last ten games, although they faced a setback in their most recent outing, losing 31-28 to the Carolina Panthers. Despite this loss, they averaged 28.7 points scored per game while allowing only 18.2 points, showcasing their offensive strength and defensive resilience. In contrast, the Cardinals had a dismal stretch, going 1-9 in their last ten games, including a four-game losing streak. They averaged 21.8 points scored but allowed 26.8 points, indicating significant defensive vulnerabilities.
Playing at home, the Cardinals had a record of 0-5, while their away record stood at 1-4. This home disadvantage was evident as they struggled to find form at State Farm Stadium. The Rams, on the other hand, had a solid away record of 3-2, further emphasizing their capability to perform outside of their home venue.
In their previous encounters, the teams were evenly matched with a record of 1-1 in their last two meetings. The Cardinals won the first game of the 2024 season 41-10 at home, while the Rams took the second match later that season with a narrow 13-9 victory on the road.
Injuries played a significant role in the game, particularly for the Cardinals. Key players such as James Conner and Zachary Carter were on Injured Reserve, while Jeremiyah Love and Will Johnson were listed as questionable. The Rams also dealt with injuries, including Alex Johnson on Injured Reserve and Myles Garrett and Puka Nacua both listed as questionable.
The betting market reflected the Rams' dominance, with DraftKings setting the spread at 9.5 points in favor of Los Angeles. The total points line was set at 49.5, with both the over and under priced at -110. The moneyline indicated significant confidence in the Rams, with odds of -485, while the Cardinals were at +370.
The game conditions were typical for December, with players needing to adapt to cooler temperatures. Fans were treated to a matchup that showcased the Rams' offensive prowess and the Cardinals' ongoing struggles. Viewers were encouraged to watch for the Rams' ability to exploit the Cardinals' defensive weaknesses, as well as the performance of the Cardinals' offense in trying to overcome their recent challenges.
Odds
| Book | Spread | Total | Moneyline |
|---|---|---|---|
| DraftKings | LAR -9.5 | 49.5 o -110 / u -110 | Los Angeles Rams -485 · Arizona Cardinals +370 |
Injury report
- Jeremiyah LoveQuestionableAnkleArizona Cardinals
- Zachary CarterInjured ReserveKneeArizona Cardinals
- Will JohnsonQuestionableLower BodyArizona Cardinals
- Tip ReimanOutAnkleArizona Cardinals
- James ConnerInjured ReserveFootArizona Cardinals
- Alex JohnsonInjured ReserveUndisclosedLos Angeles Rams
- Myles GarrettQuestionableKneeLos Angeles Rams
- Puka NacuaQuestionableGroinLos Angeles Rams
- Justin DedichInjured ReserveUndisclosedLos Angeles Rams
- Keagen TrostInjured ReserveHamstringLos Angeles Rams
Leaders
- Passing yardsJacoby Brissett25/44, 271 YDS, 2 TD, 1 INTArizona Cardinals
- Rushing yardsJacoby Brissett4 CAR, 22 YDSArizona Cardinals
- Receiving yardsMichael Wilson11 REC, 142 YDS, 2 TDArizona Cardinals
- Passing yardsMatthew Stafford22/31, 281 YDS, 3 TDLos Angeles Rams
- Rushing yardsBlake Corum12 CAR, 128 YDS, 2 TDLos Angeles Rams
- Receiving yardsPuka Nacua7 REC, 167 YDS, 2 TDLos Angeles Rams
Recent form
Arizona Cardinals
Last 10: 1-9Streak L421.8 scored · 26.8 allowed per game0-5 at home
- L17-20at Tampa Bay BuccaneersNov 30
- L24-27vs Jacksonville JaguarsNov 23
- L22-41vs San Francisco 49ersNov 16
- L22-44at Seattle SeahawksNov 9
- W27-17at Dallas CowboysNov 4
- L23-27vs Green Bay PackersOct 19
- L27-31at Indianapolis ColtsOct 12
- L21-22vs Tennessee TitansOct 5
- L20-23vs Seattle SeahawksSep 26
- L15-16at San Francisco 49ersSep 21
Los Angeles Rams
Last 10: 7-3Streak L128.7 scored · 18.2 allowed per game3-2 away
- L28-31at Carolina PanthersNov 30
- W34-7vs Tampa Bay BuccaneersNov 24
- W21-19vs Seattle SeahawksNov 16
- W42-26at San Francisco 49ersNov 9
- W34-10vs New Orleans SaintsNov 2
- W35-7at Jacksonville JaguarsOct 19
- W17-3at Baltimore RavensOct 12
- L23-26vs San Francisco 49ersOct 3
- W27-20vs Indianapolis ColtsSep 28
- L26-33at Philadelphia EaglesSep 21
Standings
| Team | Lost | Points against | Points for | Tied | Win % | Won | Overall |
|---|---|---|---|---|---|---|---|
| Los Angeles | 0 | 30 | 74 | 0 | 1.000 | 3 | 3-0 |
| San Francisco | 1 | 48 | 72 | 0 | .667 | 2 | 2-1 |
| Arizona | 3 | 123 | 108 | 0 | .250 | 1 | 1-3 |
| Seattle | 2 | 45 | 32 | 1 | .167 | 0 | 0-2-1 |
Box score
| Stat | Los Angeles Rams | Arizona Cardinals |
|---|---|---|
| First downs | 30 | 17 |
| First downs passing | 13 | 15 |
| First downs rushing | 15 | 2 |
| First downs by penalty | 2 | 0 |
| Third downs | 3-8 | 4-12 |
| Fourth downs | 0-0 | 0-1 |
| Offensive plays | 67 | 61 |
| Total yards | 530 | 314 |
| Yards per play | 7.9 | 5.1 |
| Drives | 11 | 11 |
| Net passing yards | 281 | 263 |
| Completions | 22/31 | 25/44 |
| Yards per pass | 9.1 | 5.6 |
| Interceptions thrown | 0 | 1 |
| Sacks allowed | 0-0 | 3-8 |
| Rushing yards | 249 | 51 |
| Rushing attempts | 36 | 14 |
| Yards per rush | 6.9 | 3.6 |
| Red zone trips | 3-4 | 2-4 |
| Penalties | 5-30 | 7-42 |
| Turnovers | 0 | 1 |
| Fumbles lost | 0 | 0 |
| Defensive touchdowns | 0 | 0 |
| Time of possession | 35:04 | 24:56 |
Win probability
Above the line favours Arizona Cardinals, below favours Los Angeles Rams.
Venue
- State Farm StadiumGlendale, AZ
- Attendance61970
- OfficialsBarry Anderson, Ronald Torbert, Keith Washington, Ryan Dickson, Brian Bolinger, Frank LeBlanc, Courtney Brown
Elsewhere
- 2026 Fantasy Football Draft Guide: Rankings, mock drafts and analysis
- Fantasy football fast facts: Quick-hit notes to get you ready for your draft
- Mike Clay's Playbook, Part 3: How to manage your team postdraft
- NFL players, coaches, GMs under the most pressure in 2026
- Who calls plays for every NFL team in 2026? What to know
- How Panthers QB Bryce Young, playcaller Brad Idzik will mesh in 2026
Picks for NFL
NFL rules and settlement
These two, other days
- Cardinals Edge Rams in Close NFL ClashOct 18, 2026
- Rams Defeat Cardinals 37-20 at SoFi StadiumJan 4, 2026