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NFL · Final

Buffalo Bills Defeat New Orleans Saints 31-19

Sunday, September 28, 2025, 1:00 PM ET · Highmark Stadium (Old)

Buffalo Bills 31, New Orleans Saints 19, final. Our NFL picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won New Orleans Saints vs Buffalo Bills?

Buffalo Bills beat New Orleans Saints 31-19 at Highmark Stadium (Old) on September 28, 2025.

The Buffalo Bills continued their dominant home performance with a convincing 31-19 victory over the New Orleans Saints at Highmark Stadium. This win marks the Bills' fifth consecutive victory at home, improving their record to 4-0 in the current season, while the Saints remain winless on the road, falling to 0-4. The Bills have established themselves as a formidable force at home, boasting a perfect record and an impressive average of 33.7 points scored per game over their last ten outings, while allowing an average of 24.6 points.

In their last ten games, the Bills have a record of 8-2, with a current winning streak of three games. Their recent form has been highlighted by high-scoring affairs, including a narrow win against the Baltimore Ravens, where they edged out a 41-40 victory. The Bills' offense has been firing on all cylinders, averaging 31.6 points in their last five games, showcasing their ability to put points on the board consistently.

On the other hand, the New Orleans Saints have struggled significantly, with a record of 2-8 over their last ten games and a disheartening seven-game losing streak. Their average points scored per game stands at a mere 15.8, while they have allowed an average of 24.2 points. This offensive struggle was evident in their last outing, where they suffered a heavy defeat against the Seattle Seahawks, losing 13-44. The Saints' performance has been particularly concerning, as they have averaged only 15.2 points in their last five games, indicating a significant drop in offensive production.

At home, the Bills have been nearly unbeatable, with a perfect home record of 6-0, while the Saints have struggled on the road, managing only one win out of six attempts this season. This disparity in home and away performance has been a critical factor in both teams' current standings.

In terms of previous meetings, the Bills and Saints have faced off multiple times, but the most recent encounter showcased the Bills' offensive prowess and defensive resilience. The Bills' ability to score and maintain control of the game has been a hallmark of their recent success.

Injury concerns could also play a role in both teams' performances. The Bills have several players listed as questionable, including Khalil Shakir (undisclosed), Keon Coleman (foot), and Ty Johnson (lower leg). Additionally, Tyrell Shavers is out with a knee injury (ACL), while Zane Durant is on injured reserve with an undisclosed issue. The Saints also have key players affected, with Kendre Miller listed as questionable (undisclosed) and several others, including Lorenzo Styles Jr., Michael Heldman, Jaylan Ford, and David Long Jr., on injured reserve.

The betting market reflected a strong belief in the Bills' chances, pricing them with a home win probability of 1.0, indicating their overwhelming favor as the stronger team in this matchup.

The weather conditions at Highmark Stadium were conducive for football, which likely contributed to the Bills' strong performance. Fans and viewers should have watched for the Bills' explosive offense, which has been a key factor in their recent success, as well as their ability to capitalize on defensive mistakes from the Saints. The game served as a reminder of the Bills' offensive capabilities and the struggles that the Saints face as they continue to seek their first road win of the season.

Injury report

  • Khalil ShakirQuestionableUndisclosedBuffalo Bills
  • Keon ColemanQuestionableFootBuffalo Bills
  • Ty JohnsonQuestionableLower LegBuffalo Bills
  • Zane DurantInjured ReserveUndisclosedBuffalo Bills
  • Tyrell ShaversOutKnee - ACLBuffalo Bills
  • Kendre MillerQuestionableUndisclosedNew Orleans Saints
  • Lorenzo Styles Jr.Injured ReserveCalfNew Orleans Saints
  • Michael HeldmanInjured ReserveUndisclosedNew Orleans Saints
  • Jaylan FordInjured ReserveUndisclosedNew Orleans Saints
  • David Long Jr.Injured ReserveUndisclosedNew Orleans Saints

Leaders

  • Passing yardsJosh Allen16/22, 209 YDS, 2 TD, 1 INTBuffalo Bills
  • Rushing yardsJames Cook III22 CAR, 117 YDS, 1 TDBuffalo Bills
  • Receiving yardsKhalil Shakir5 REC, 69 YDS, 1 TDBuffalo Bills
  • Passing yardsSpencer Rattler18/27, 126 YDS, 1 TDNew Orleans Saints
  • Rushing yardsAlvin Kamara15 CAR, 70 YDSNew Orleans Saints
  • Receiving yardsRashid Shaheed4 REC, 47 YDSNew Orleans Saints

Recent form

Buffalo Bills

Last 10: 8-2Streak W333.7 scored · 24.6 allowed per game6-0 at home

  • W31-21vs Miami DolphinsSep 19
  • W30-10at New York JetsSep 14
  • W41-40vs Baltimore RavensSep 8
  • L16-23at New England PatriotsJan 5
  • W40-14vs New York JetsDec 29
  • W24-21vs New England PatriotsDec 22
  • W48-42at Detroit LionsDec 15
  • L42-44at Los Angeles RamsDec 8
  • W35-10vs San Francisco 49ersDec 2
  • W30-21vs Kansas City ChiefsNov 17

New Orleans Saints

Last 10: 2-8Streak L715.8 scored · 24.2 allowed per game1-3 away

  • L13-44at Seattle SeahawksSep 21
  • L21-26vs San Francisco 49ersSep 14
  • L13-20vs Arizona CardinalsSep 7
  • L19-27at Tampa Bay BuccaneersJan 5
  • L10-25vs Las Vegas RaidersDec 29
  • L0-34at Green Bay PackersDec 24
  • L19-20vs Washington CommandersDec 15
  • W14-11at New York GiantsDec 8
  • L14-21vs Los Angeles RamsDec 1
  • W35-14vs Cleveland BrownsNov 17

Standings

TeamLostPoints againstPoints forTiedWin %WonOverall
Carolina189970.75033-1
Tampa Bay150400.66722-1
Atlanta145580.66722-1
New Orleans282470.33311-2
Buffalo0488801.00033-0
New England171501.50011-1-1
New York247390.33311-2
Miami363220.00000-3

Box score

StatNew Orleans SaintsBuffalo Bills
First downs2220
First downs passing710
First downs rushing149
First downs by penalty11
Third downs5-133-10
Fourth downs0-20-1
Offensive plays6557
Total yards298356
Yards per play4.66.2
Drives1011
Net passing yards109191
Completions18/2816/22
Yards per pass3.57.6
Interceptions thrown11
Sacks allowed3-173-18
Rushing yards189165
Rushing attempts3432
Yards per rush5.65.2
Red zone trips2-42-3
Penalties4-4111-55
Turnovers11
Fumbles lost00
Defensive touchdowns00
Time of possession28:3931:21

Win probability

Above the line favours Buffalo Bills, below favours New Orleans Saints.

Venue

  • Highmark Stadium (Old)Orchard Park, NY
  • Attendance71017
  • OfficialsTom Stephan, Mark Pellis, Jabir Walker, Land Clark, Dominique Pender, Jeff Hutcheon, Courtney Brown

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.