NCAAB · Final

Louisville Cardinals Defeat Notre Dame Fighting Irish 76-65

Wednesday, February 4, 2026, 7:00 PM ET · KFC Yum! Center

Louisville Cardinals 76, Notre Dame Fighting Irish 65, final. Our NCAAB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Notre Dame Fighting Irish vs Louisville Cardinals?

Louisville Cardinals beat Notre Dame Fighting Irish 76-65 at KFC Yum! Center on February 4, 2026.

Who was favored in Notre Dame Fighting Irish vs Louisville Cardinals?

Louisville Cardinals were the favorite at DraftKings, moneyline -3600 (about 97% implied). The favorite won.

The Louisville Cardinals secured a victory against the Notre Dame Fighting Irish with a final score of 76-65 at the KFC Yum! Center. This matchup was particularly noteworthy as it showcased the contrasting fortunes of both teams in the NCAAB season. Louisville, with a home record of 16-6, has been performing well, while Notre Dame, sitting at 11-12, has struggled, especially in recent outings.

In their last ten games, Louisville has a record of 6-4, currently riding a one-game winning streak after defeating the SMU Mustangs 88-74 on January 31. The Cardinals have averaged 80.3 points per game during this stretch while allowing 71.6 points. Their recent form includes notable victories against Virginia Tech and Pittsburgh, along with losses to Duke and Virginia. At home, Louisville has a record of 4-2 in their last six games.

Conversely, Notre Dame has faced significant challenges, with a record of 2-8 in their last ten games and currently on a two-game losing streak. Their scoring average during this period is 69.9 points per game, while they have allowed 77.1 points. Their most recent game ended in a loss against Syracuse, where they were defeated 72-86. The Fighting Irish have struggled both at home and on the road, with a home record of 1-4 and an away record of 1-4 in their last five games.

In terms of head-to-head matchups, this was the second meeting between the two teams this season. In their previous encounter on February 17, 2025, Louisville emerged victorious with a score of 75-60, further establishing their dominance over Notre Dame in recent matchups.

Injury reports indicated that both teams were relatively healthy, which allowed them to field their best lineups. This aspect contributed to the competitive nature of the game, as both teams aimed to capitalize on their strengths.

The betting market, as provided by DraftKings, had Louisville favored by 19.5 points, with a total set at 155.5. The odds reflected the Cardinals' strong home performance and the Fighting Irish's struggles this season. Louisville's moneyline was set at -3600, while Notre Dame's was at +1500, indicating a significant expectation of a home victory.

The game conditions were favorable, with a typical indoor basketball environment at the KFC Yum! Center, which is known for its passionate fan base and vibrant atmosphere. This setting likely provided an additional boost to the Cardinals as they aimed to defend their home court.

Throughout the game, viewers were treated to a display of offensive skill from both teams. Notable scoring plays included a driving layup by Ryan Conwell for Notre Dame, as well as several three-point shots from Brady Koehler and Cole Certa. Louisville's Kasean Pryor contributed with a powerful dunk, showcasing the team's athleticism and ability to finish strong around the rim. The final moments of the game featured a flurry of scoring that kept the audience engaged until the final buzzer.

In conclusion, the Louisville Cardinals' victory over the Notre Dame Fighting Irish highlighted their strong home performance and ability to capitalize on the struggles of their opponent. With this win, Louisville continues to solidify its position in the NCAAB landscape, while Notre Dame will need to regroup and address their recent challenges as they move forward in the season.

Odds

Book	Spread	Total	Moneyline
DraftKings	LOU -19.5	155.5 o -110 / u -110	Notre Dame Fighting Irish +1500 · Louisville Cardinals -3600

What these prices pay on $100 · What these numbers mean

Leaders

PointsIsaac McKneely13Louisville Cardinals
AssistsMikel Brown Jr.6Louisville Cardinals
ReboundsKhani Rooths12Louisville Cardinals
PointsCole Certa18Notre Dame Fighting Irish
AssistsJalen Haralson5Notre Dame Fighting Irish
ReboundsCarson Towt10Notre Dame Fighting Irish

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