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NFL · Final

49ers Dominate Browns in NFL Showdown

Sunday, November 30, 2025, 1:00 PM ET · Huntington Bank Field

San Francisco 49ers 26, Cleveland Browns 8, final. Our NFL picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won San Francisco 49ers vs Cleveland Browns?

San Francisco 49ers beat Cleveland Browns 26-8 at Huntington Bank Field on November 30, 2025.

Who was favored in San Francisco 49ers vs Cleveland Browns?

San Francisco 49ers were the favorite at DraftKings, moneyline -250 (about 71% implied). The favorite won.

The San Francisco 49ers showcased their strength with a decisive 26-8 victory over the Cleveland Browns at Huntington Bank Field. This matchup highlighted the contrasting fortunes of both teams, with the 49ers improving their record to 10-4, while the Browns fell to 3-10. The game was particularly significant for the 49ers, who have been in strong form, winning their last three games leading into this matchup, while the Browns have struggled, winning only one of their last five.

The Browns entered the game with a home record of 2-6, having averaged 17.0 points scored and 22.7 points allowed over their last ten games. Their recent form included a win against the Las Vegas Raiders and losses to teams like the Baltimore Ravens and the New York Jets. In contrast, the 49ers boasted a solid away record of 6-4, averaging 23.8 points scored and 22.7 points allowed in their last ten games. Their recent victories included a win against the Carolina Panthers and a high-scoring affair against the Arizona Cardinals.

In terms of injuries, the Browns were significantly impacted, with four players on Injured Reserve, including Kalia Davis and Edefuan Ulofoshio. Additionally, Isaiah Bond was listed as questionable due to a concussion. The 49ers also faced injury concerns, with key players such as Nick Bosa and George Kittle listed as questionable, which could have affected their performance.

The betting market, as provided by DraftKings, had the 49ers favored by 5.5 points, with a total set at 35.5. The odds reflected the 49ers' stronger season performance compared to the struggling Browns. The conditions at Huntington Bank Field were conducive to a competitive game, though the 49ers' execution ultimately overshadowed any home advantage the Browns might have hoped for.

Viewers were treated to a display of the 49ers' offensive prowess, as they managed to score consistently throughout the game. The Browns, on the other hand, struggled to find their rhythm, leading to their disappointing scoreline. The final result underscored the disparity in the teams' current form and set the stage for the 49ers as they continue their playoff push.

Odds

BookSpreadTotalMoneyline
DraftKingsSF -5.5 35.5 o -108 / u -112 San Francisco 49ers -250 · Cleveland Browns +205

What these prices pay on $100 · What these numbers mean

Injury report

  • Kalia DavisInjured ReserveQuadricepsCleveland Browns
  • Edefuan UlofoshioInjured ReserveBicepsCleveland Browns
  • Elijah ChatmanInjured ReserveQuadricepsCleveland Browns
  • Travis BellInjured ReserveEyeCleveland Browns
  • Isaiah BondQuestionableConcussionCleveland Browns
  • Sam OkuayinonuQuestionableFootSan Francisco 49ers
  • Kyle JuszczykQuestionableFingerSan Francisco 49ers
  • Nick BosaQuestionableKnee - ACLSan Francisco 49ers
  • Mike EvansQuestionableGroinSan Francisco 49ers
  • George KittleQuestionableAchillesSan Francisco 49ers

Leaders

  • Passing yardsShedeur Sanders16/25, 149 YDS, 1 TDCleveland Browns
  • Rushing yardsQuinshon Judkins23 CAR, 91 YDSCleveland Browns
  • Receiving yardsHarold Fannin Jr.3 REC, 43 YDS, 1 TDCleveland Browns
  • Passing yardsBrock Purdy16/29, 168 YDS, 1 TDSan Francisco 49ers
  • Rushing yardsChristian McCaffrey20 CAR, 53 YDS, 1 TDSan Francisco 49ers
  • Receiving yardsGeorge Kittle4 REC, 67 YDSSan Francisco 49ers

Recent form

Cleveland Browns

Last 10: 3-7Streak W117 scored · 22.7 allowed per game2-2 at home

  • W24-10at Las Vegas RaidersNov 23
  • L16-23vs Baltimore RavensNov 16
  • L20-27at New York JetsNov 9
  • L13-32at New England PatriotsOct 26
  • W31-6vs Miami DolphinsOct 19
  • L9-23at Pittsburgh SteelersOct 12
  • L17-21vs Minnesota VikingsOct 5
  • L10-34at Detroit LionsSep 28
  • W13-10vs Green Bay PackersSep 21
  • L17-41at Baltimore RavensSep 14

San Francisco 49ers

Last 10: 6-4Streak W223.8 scored · 22.7 allowed per game3-2 away

  • W20-9vs Carolina PanthersNov 25
  • W41-22at Arizona CardinalsNov 16
  • L26-42vs Los Angeles RamsNov 9
  • W34-24at New York GiantsNov 2
  • L15-26at Houston TexansOct 26
  • W20-10vs Atlanta FalconsOct 20
  • L19-30at Tampa Bay BuccaneersOct 12
  • W26-23at Los Angeles RamsOct 3
  • L21-26vs Jacksonville JaguarsSep 28
  • W16-15vs Arizona CardinalsSep 21

Standings

TeamLostPoints againstPoints forTiedWin %WonOverall
Los Angeles0307401.00033-0
San Francisco148720.66722-1
Arizona31231080.25011-3
Seattle245321.16700-2-1
Cincinnati0367301.00033-0
Baltimore0137801.00033-0
Cleveland278540.33311-2
Pittsburgh254550.33311-2

Box score

StatSan Francisco 49ersCleveland Browns
First downs1915
First downs passing117
First downs rushing78
First downs by penalty10
Third downs11-173-11
Fourth downs0-00-4
Offensive plays6460
Total yards252253
Yards per play3.94.2
Drives119
Net passing yards161115
Completions16/3017/26
Yards per pass5.24.0
Interceptions thrown00
Sacks allowed1-73-34
Rushing yards91138
Rushing attempts3331
Yards per rush2.84.5
Red zone trips3-50-0
Penalties3-114-25
Turnovers02
Fumbles lost02
Defensive touchdowns00
Time of possession30:1029:50

Win probability

Above the line favours Cleveland Browns, below favours San Francisco 49ers.

Venue

  • Huntington Bank FieldCleveland, OH
  • Attendance64042

Elsewhere

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.