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NFL · Final

49ers Defeat Rams 27-7 in NFL Clash

Thursday, September 10, 2026, 8:35 PM ET · Melbourne Cricket Ground

Quick answers

Who won San Francisco 49ers vs Los Angeles Rams?

San Francisco 49ers beat Los Angeles Rams 27-7 at Melbourne Cricket Ground on September 10, 2026.

Who was favored in San Francisco 49ers vs Los Angeles Rams?

Los Angeles Rams were the favorite at DraftKings, moneyline -218 (about 69% implied). The underdog won.

In a decisive matchup, the San Francisco 49ers triumphed over the Los Angeles Rams with a final score of 27-7. The game took place at the Melbourne Cricket Ground, marking a significant moment as both teams sought to establish their standing in the NFL. The Rams entered the game with a home record of 0-1, while the 49ers boasted an away record of 1-0, setting the stage for a competitive encounter.

The Rams, despite their recent form showing a record of 7-3 over their last ten games, struggled to find their rhythm in this contest. They had averaged 34.3 points scored and allowed 22.9 points during this stretch, but their performance against the 49ers fell short of these averages. In their last five games, the Rams had a record of 3-2, scoring an average of 36.8 points while allowing 27.2 points. However, they were unable to capitalize on their home advantage, where they had previously maintained a perfect home record of 5-0.

Conversely, the 49ers, who also held a record of 7-3 in their last ten games, faced a recent setback with a loss in their most recent outing. They had averaged 29.2 points scored and allowed 23.3 points during this period. Their away record stood at 4-1, showcasing their ability to perform on the road. The 49ers had previously met the Rams earlier in the season, where they lost 42-26, but they managed to turn the tables in this encounter.

In terms of injuries, the Rams had several key players impacted. Davis Allen and Kam Curl were both listed as questionable, while Max Klare, CJ Daniels, and Tutu Atwell were ruled out due to coach's decisions. The 49ers also faced challenges with Jake Tonges listed as questionable due to a knee injury, and De'Zhaun Stribling, Ephesians Prysock, Tatum Bethune, and Jordan Watkins all ruled out for the game.

The betting market, as provided by DraftKings, had the Rams as 3.5-point favorites with a total set at 47.5. The odds indicated a home moneyline of -218 for the Rams and +180 for the 49ers, reflecting the expectations of a close contest. However, the final result highlighted the 49ers’ ability to exceed these expectations.

Weather conditions were not detailed in the block, but the matchup was played in a neutral venue, which often influences team performance. Viewers were able to watch for the 49ers' strong defensive plays and their ability to capitalize on the Rams' mistakes, which ultimately led to their victory.

This game adds another chapter to the ongoing rivalry between the Rams and the 49ers, with their head-to-head record now standing at 1-1 for the current season. The Rams will need to regroup as they look to improve their performance in future games, while the 49ers will aim to build on this momentum.

What we said beforehand

The upcoming NFL matchup between the Los Angeles Rams and the San Francisco 49ers at the Melbourne Cricket Ground promises to be an intriguing contest, especially since both teams enter the game with a record of 0-0. This fixture is notable not just for the teams' storied rivalry, but also for the setting, as it marks a rare international game in the league's regular season schedule. Kickoff is set for September 11, 2026, at 00:35 UTC.

Both teams have shown strong recent form, with the Rams boasting a record of 7-3 in their last ten games, including a current winning streak of one game. Their last five games include a notable 34-0 victory against the New Orleans Saints and a close 20-18 win over the Los Angeles Chargers. The Rams have averaged 34.3 points scored at home while allowing 22.9 points, indicating a potent offense complemented by a reasonably effective defense.

The 49ers also hold a 7-3 record in their last ten games, but they are currently on a one-game losing streak. Their recent performances include a 41-17 victory over the Los Angeles Chargers and an 18-12 win against the Las Vegas Raiders. The 49ers have averaged 29.2 points scored while allowing 23.3 points in their recent outings, showcasing their offensive capabilities, although they have faced some challenges defensively.

In terms of home and away performance, the Rams have been particularly strong at home, with a perfect 5-0 record in their last five home games. In contrast, the 49ers have a solid away record of 4-1, indicating their ability to compete on the road. This matchup will test the Rams' home advantage against the 49ers' resilience as visitors.

Historically, the two teams have split their last two meetings, with the Rams winning 42-26 in their last encounter on November 9, 2025, and the 49ers taking the earlier match 26-23 on October 3, 2025. This recent history adds an extra layer of competitiveness to the fixture, as both teams will look to assert dominance in their rivalry.

Injury reports indicate that both teams will be missing key players. The Rams have several notable absences, including Tutu Atwell, Ty Simpson, Aaron Donald, Max Klare, and Bill Murray, all ruled out due to coach's decisions. For the 49ers, Ephesians Prysock, Tatum Bethune, Jordan Watkins, and Jordan James are out, while Alfred Collins is on injured reserve due to a knee injury. The absence of these players could impact both teams' strategies and depth.

The betting market has the Rams favored by 3.5 points according to DraftKings, with a total set at 47.5 points. The odds suggest a competitive encounter, with the Rams' moneyline at -218.0 and the 49ers at 180.0, reflecting the perceived advantage of the Rams playing at home.

Conditions at the Melbourne Cricket Ground are expected to be conducive for football, although specific weather details have not been provided. Fans can anticipate an exciting matchup filled with high stakes as both teams aim to start their seasons on a positive note. Viewers should watch for the Rams' offensive execution and how they adapt without key players, as well as the 49ers' response to their recent form and ability to capitalize on any defensive lapses from the Rams.

Odds

BookSpreadTotalMoneyline
DraftKingsLAR -3.5 47.5 o -115 / u -105 San Francisco 49ers +180 · Los Angeles Rams -218

What these prices pay on $100 · What these numbers mean

Injury report

  • Davis AllenQuestionableHeadLos Angeles Rams
  • Kam CurlQuestionableAnkleLos Angeles Rams
  • Max KlareOutCoach's DecisionLos Angeles Rams
  • CJ DanielsOutCoach's DecisionLos Angeles Rams
  • Tutu AtwellOutCoach's DecisionLos Angeles Rams
  • Jake TongesQuestionableKneeSan Francisco 49ers
  • De'Zhaun StriblingOutAnkleSan Francisco 49ers
  • Ephesians PrysockOutCoach's DecisionSan Francisco 49ers
  • Tatum BethuneOutCoach's DecisionSan Francisco 49ers
  • Jordan WatkinsOutCoach's DecisionSan Francisco 49ers

Leaders

  • Passing yardsMatthew Stafford15/25, 155 YDS, 1 INTLos Angeles Rams
  • Rushing yardsBlake Corum10 CAR, 54 YDSLos Angeles Rams
  • Receiving yardsPuka Nacua5 REC, 74 YDSLos Angeles Rams
  • Passing yardsBrock Purdy25/34, 205 YDS, 3 TD, 1 INTSan Francisco 49ers
  • Rushing yardsChristian McCaffrey10 CAR, 68 YDSSan Francisco 49ers
  • Receiving yardsDemarcus Robinson2 REC, 50 YDS, 1 TDSan Francisco 49ers

Recent form

Los Angeles Rams

Last 10: 7-3Streak W134.3 scored · 22.9 allowed per game5-0 at home

  • W37-20vs Arizona CardinalsJan 4
  • L24-27at Atlanta FalconsDec 30
  • L37-38at Seattle SeahawksDec 19
  • W41-34vs Detroit LionsDec 14
  • W45-17at Arizona CardinalsDec 7
  • L28-31at Carolina PanthersNov 30
  • W34-7vs Tampa Bay BuccaneersNov 24
  • W21-19vs Seattle SeahawksNov 16
  • W42-26at San Francisco 49ersNov 9
  • W34-10vs New Orleans SaintsNov 2

San Francisco 49ers

Last 10: 7-3Streak L129.2 scored · 23.3 allowed per game4-1 away

  • L3-13vs Seattle SeahawksJan 4
  • W42-38vs Chicago BearsDec 29
  • W48-27at Indianapolis ColtsDec 23
  • W37-24vs Tennessee TitansDec 14
  • W26-8at Cleveland BrownsNov 30
  • W20-9vs Carolina PanthersNov 25
  • W41-22at Arizona CardinalsNov 16
  • L26-42vs Los Angeles RamsNov 9
  • W34-24at New York GiantsNov 2
  • L15-26at Houston TexansOct 26

Standings

TeamLostPoints againstPoints forTiedWin %WonOverall
San Francisco072701.00011-0
Seattle0101301.00011-0
Arizona0000.00000-0
Los Angeles12770.00000-1

Box score

StatSan Francisco 49ersLos Angeles Rams
First downs2315
First downs passing126
First downs rushing107
First downs by penalty12
Third downs7-122-9
Fourth downs0-01-3
Offensive plays6457
Total yards379290
Yards per play5.95.1
Drives910
Net passing yards205168
Completions25/3417/28
Yards per pass6.06.0
Interceptions thrown11
Sacks allowed0-00-0
Rushing yards174122
Rushing attempts3029
Yards per rush5.84.2
Red zone trips2-31-3
Penalties2-214-43
Turnovers12
Fumbles lost01
Defensive touchdowns00
Time of possession33:5026:10

Win probability

Above the line favours Los Angeles Rams, below favours San Francisco 49ers.

Venue

  • Melbourne Cricket GroundMelbourne
  • OfficialsRusty Baynes, Sean Petty, Scott Helverson, Jim Quirk, Alex Kemp, Mike Carr, Brandon Ellison

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.