Southern Miss Golden Eagles vs Iowa State Cyclones prediction & odds

The upcoming matchup between the Iowa State Cyclones and the Southern Miss Golden Eagles is set to take place at Hilton Coliseum on November 7, 2026. This game is particularly intriguing given the contrasting records of both teams at this early stage of the season.

Iowa State's recent form has been a mixed bag. In their last five games, they have recorded two wins and three losses, with a notable recent defeat against the Memphis Tigers, where they lost 80-76. In their last ten games overall, Iowa State has a record of 5-5, currently on a two-game losing streak. They have averaged 75.2 points scored per game while allowing an average of 68.2 points to their opponents. Key players for the Cyclones include Ryan Prather Jr., who leads the team with an average of 19.0 points per game, and Tre Singleton, who is averaging 11.0 rebounds.

On the other hand, Southern Miss comes into this game with a more favorable recent record. They have won seven of their last ten games, including a decisive victory over the Tougaloo Bulldogs, where they won 82-35. Their last five games show a record of 4-1, averaging 81.0 points scored per game while allowing 68.6 points. Isaac Taveras stands out for the Golden Eagles, averaging 12.0 points and 9.0 rebounds per game.

When considering home and away performances, Iowa State has a home record of 3-2 in their last five games, scoring an average of 81.6 points and allowing 64.4 points. In contrast, Southern Miss has a strong away record of 3-2, which includes their recent win against Troy Trojans.

In terms of betting lines, DraftKings has set the spread at Iowa State -30.5, with a total of 145.5 points for the game. The moneyline reflects a significant favorite for Iowa State at -100000, while Southern Miss is listed at 5000.

As for injuries, the block does not provide specific details, so it remains unclear how either team may be impacted in that regard.

Fans should pay attention to the performance of Iowa State's Ryan Prather Jr. as he has been a key scorer for the Cyclones. Additionally, Southern Miss's Isaac Taveras will be crucial in the paint, particularly in rebounding, which could influence the game's outcome. The matchup promises to be an exciting one, with both teams looking to establish momentum early in the season.