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MLB · Final

Cardinals Complete Sweep Over Pirates in Close Contest

Monday, April 27, 2026, 6:40 PM ET · PNC Park

St. Louis Cardinals 4, Pittsburgh Pirates 2, final. Our MLB picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won St. Louis Cardinals vs Pittsburgh Pirates?

St. Louis Cardinals beat Pittsburgh Pirates 4-2 at PNC Park on April 27, 2026.

Who was favored in St. Louis Cardinals vs Pittsburgh Pirates?

Pittsburgh Pirates were the favorite at DraftKings, moneyline -118 (about 54% implied). The underdog won.

In a tightly contested game at PNC Park, the St. Louis Cardinals defeated the Pittsburgh Pirates 4-2, completing a four-game series sweep. This victory marks a significant achievement for the Cardinals, who have now won all four matchups in this series against the Pirates. The game showcased a mix of early offense and late-game drama, with both teams displaying moments of brilliance.

The Pirates entered this game with a home record of 16-13 and a recent form of 5-5 over their last ten games. They had been averaging 4.7 runs scored per game while allowing 4.3 runs. However, they were on a one-game losing streak, having lost their previous match against the Milwaukee Brewers 0-5. The Cardinals, on the other hand, had an away record of 15-13 and also stood at 5-5 in their last ten games, but they were struggling with a three-game losing streak, having lost their last match against the Seattle Mariners 2-3.

The scoring in this game began in the first inning when Ryan O'Hearn singled to right, bringing Lowe home for the Pirates. They extended their lead in the second inning when Mangum singled to right, scoring Gonzales, putting the Pirates ahead 2-0. However, the Cardinals fought back in the ninth inning, starting with Pagés hitting a home run to left field, narrowing the gap to 2-1. JJ Wetherholt then homered to right center, tying the game at 2-2. The Cardinals took the lead for good when Fermín doubled to left, scoring Scott II and Burleson, with Walker advancing to third, ultimately sealing the game at 4-2.

In terms of injuries, the Pirates were missing several key players, including Konnor Griffin, Mitch Keller, and Endy Rodriguez, all on the 60-Day Injured List. Ryan O'Hearn was also on the 10-Day Injured List due to a quadriceps issue. The Cardinals had Everson Pereira on the 10-Day Injured List with a hand injury, while Ramon Urias was listed as day-to-day with an arm issue. Masyn Winn, Andre Pallante, and JJ Wetherholt were also dealing with injuries, impacting the Cardinals' lineup.

The betting market, as reported by DraftKings, had the Pirates at -118 on the money line, while the Cardinals were at -102. The spread was set at 1.5, and the total runs over/under was 8.0, with both sides priced at -110 for the over and under. This reflected a competitive matchup between the two teams, though the Cardinals ultimately proved more effective in clutch situations.

Conditions at PNC Park were typical for a spring evening, providing a solid backdrop for the game. Fans witnessed a mix of solid pitching and timely hitting, with the Cardinals demonstrating resilience in their comeback effort. The Pirates, despite their loss, showed flashes of offensive potential, particularly early in the game.

Overall, this game highlighted the Cardinals' ability to capitalize on late-game opportunities, while the Pirates will need to regroup as they look to improve their performance moving forward.

Odds

BookSpreadTotalMoneyline
DraftKingsPIT -118 8 o -110 / u -110 St. Louis Cardinals -102 · Pittsburgh Pirates -118

What these prices pay on $100 · What these numbers mean

Injury report

  • Konnor Griffin60-Day-ILFingerPittsburgh Pirates
  • Ryan O'Hearn10-Day-ILQuadricepsPittsburgh Pirates
  • Mitch Keller60-Day-ILArmPittsburgh Pirates
  • Endy Rodriguez60-Day-ILHipPittsburgh Pirates
  • Everson Pereira10-Day-ILHandSt. Louis Cardinals
  • Ramon UriasDay-To-DayArmSt. Louis Cardinals
  • Masyn Winn10-Day-ILThumbSt. Louis Cardinals
  • Andre Pallante15-Day-ILElbowSt. Louis Cardinals
  • JJ Wetherholt10-Day-ILWristSt. Louis Cardinals

Recent form

Pittsburgh Pirates

Last 10: 5-5Streak L14.7 scored · 4.3 allowed per game2-2 at home

  • L0-5at Milwaukee BrewersApr 26
  • W6-3at Milwaukee BrewersApr 25
  • W6-0at Milwaukee BrewersApr 24
  • L1-6at Texas RangersApr 24
  • W8-4at Texas RangersApr 23
  • L1-5at Texas RangersApr 22
  • W6-3vs Tampa Bay RaysApr 19
  • L7-8vs Tampa Bay RaysApr 18
  • W5-1vs Tampa Bay RaysApr 17
  • L7-8vs Washington NationalsApr 16

St. Louis Cardinals

Last 10: 5-5Streak L34.3 scored · 4.4 allowed per game3-2 away

  • L2-3vs Seattle MarinersApr 26
  • L2-3vs Seattle MarinersApr 25
  • L1-4at Miami MarlinsApr 22
  • W5-3at Miami MarlinsApr 21
  • L3-5at Miami MarlinsApr 20
  • W7-5at Houston AstrosApr 19
  • W9-4at Houston AstrosApr 18
  • W5-3vs Cleveland GuardiansApr 15
  • W6-5vs Cleveland GuardiansApr 14
  • L3-9vs Cleveland GuardiansApr 13

Standings

TeamGames behindLostStreakWin %Won
Milwaukee-53W2.62187
Chicago962L2.55778
St. Louis1770W2.50070
Pittsburgh1972L1.48668
Cincinnati2073W2.47967

How the scoring went

  1. 1st Inning0-1O'Hearn singled to right, Lowe scored.
  2. 2nd Inning0-2Mangum singled to right, Gonzales scored.
  3. 9th Inning1-2Pagés homered to left (381 feet).
  4. 9th Inning2-2Wetherholt homered to right center (408 feet).
  5. 9th Inning4-2Fermín doubled to left, Scott II scored and Burleson scored, Walker to third.

Win probability

Above the line favours Pittsburgh Pirates, below favours St. Louis Cardinals.

Venue

  • PNC ParkPittsburgh, Pennsylvania
  • Attendance9787
  • OfficialsChris Segal, Erich Bacchus, Laz Diaz, Brian O'Nora

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.