49ers Defeat Titans 37-24 at Levi's Stadium
Sunday, December 14, 2025, 4:25 PM ET · Levi's Stadium
San Francisco 49ers 37, Tennessee Titans 24, final. Our NFL picks are sealed as a hash before kickoff and settled in public, losses included.
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Quick answers
Who won Tennessee Titans vs San Francisco 49ers?
San Francisco 49ers beat Tennessee Titans 37-24 at Levi's Stadium on December 14, 2025.
Who was favored in Tennessee Titans vs San Francisco 49ers?
San Francisco 49ers were the favorite at DraftKings, moneyline -950 (about 90% implied). The favorite won.
The San Francisco 49ers secured a convincing 37-24 victory over the Tennessee Titans at Levi's Stadium, showcasing their strength as they continue to push for a strong finish to the season. This win marks the 49ers' fourth consecutive victory, improving their record to 11-4, while the Titans fall to 2-13, highlighting the stark contrast in their seasons.
In recent form, the 49ers have been on a roll, winning six of their last ten games with a record of 6-4. They have averaged 24.8 points scored per game while allowing 22.0 points. Their last five games have seen them perform even better, with an average of 29.4 points scored and only 21.0 points allowed. The Titans, on the other hand, have struggled significantly, with a record of 2-8 in their last ten games. They have averaged just 15.0 points scored per game, while their defense has allowed an average of 26.3 points. Their recent form shows a slight improvement with a win in their last game, but the overall trend remains concerning.
At home, the 49ers have a record of 2-2, while they have excelled on the road with a 4-2 record. The Titans have not found success away from home, holding a 0-5 record in their last five road games. This matchup was particularly noteworthy as the Titans have struggled throughout the season, while the 49ers have been a formidable opponent, especially at home.
The two teams have faced each other previously, but the specifics of those encounters were not detailed in the provided information. However, the current season's context clearly indicates a dominant performance by the 49ers.
In terms of injuries, the 49ers had several players listed as questionable, including Sam Okuayinonu (foot), Kyle Juszczyk (finger), Nick Bosa (knee - ACL), Mike Evans (groin), and George Kittle (Achilles). For the Titans, Carnell Tate was also questionable with an undisclosed injury, while Kendell Brooks, Tanoh Kpassagnon, and Dorian Mausi were on injured reserve with undisclosed injuries. The impact of these injuries could have played a role in the game, particularly for the 49ers, who have key players dealing with health issues.
The betting market reflected the 49ers' dominance, with DraftKings listing them as 12.5-point favorites. The total for the game was set at 44.5, with odds of -112.0 for the over and -108.0 for the under. The moneyline indicated a strong belief in a 49ers victory, priced at -950.0 for the home team, while the Titans were listed at 625.0.
Conditions at Levi's Stadium were not specified in the block, but the home field advantage typically plays a significant role in NFL matchups. Fans watching the game would have seen a 49ers team that was efficient on offense and solid on defense, capitalizing on the Titans' struggles.
Overall, this game highlighted the disparity between the two teams in terms of current form, injuries, and home-field advantage, culminating in a decisive victory for the 49ers.
Odds
| Book | Spread | Total | Moneyline |
|---|---|---|---|
| DraftKings | SF -12.5 | 44.5 o -112 / u -108 | Tennessee Titans +625 · San Francisco 49ers -950 |
Injury report
- Sam OkuayinonuQuestionableFootSan Francisco 49ers
- Kyle JuszczykQuestionableFingerSan Francisco 49ers
- Nick BosaQuestionableKnee - ACLSan Francisco 49ers
- Mike EvansQuestionableGroinSan Francisco 49ers
- George KittleQuestionableAchillesSan Francisco 49ers
- Carnell TateQuestionableUndisclosedTennessee Titans
- Kendell BrooksInjured ReserveUndisclosedTennessee Titans
- Andre JamesQuestionableUndisclosedTennessee Titans
- Tanoh KpassagnonInjured ReserveUndisclosedTennessee Titans
- Dorian MausiInjured ReserveUndisclosedTennessee Titans
Leaders
- Passing yardsBrock Purdy23/30, 295 YDS, 3 TDSan Francisco 49ers
- Rushing yardsChristian McCaffrey22 CAR, 73 YDS, 1 TDSan Francisco 49ers
- Receiving yardsRicky Pearsall6 REC, 96 YDSSan Francisco 49ers
- Passing yardsCam Ward18/29, 170 YDS, 2 TDTennessee Titans
- Rushing yardsTony Pollard14 CAR, 104 YDS, 1 TDTennessee Titans
- Receiving yardsGunnar Helm4 REC, 49 YDS, 1 TDTennessee Titans
Recent form
San Francisco 49ers
Last 10: 6-4Streak W324.8 scored · 22 allowed per game2-2 at home
- W26-8at Cleveland BrownsNov 30
- W20-9vs Carolina PanthersNov 25
- W41-22at Arizona CardinalsNov 16
- L26-42vs Los Angeles RamsNov 9
- W34-24at New York GiantsNov 2
- L15-26at Houston TexansOct 26
- W20-10vs Atlanta FalconsOct 20
- L19-30at Tampa Bay BuccaneersOct 12
- W26-23at Los Angeles RamsOct 3
- L21-26vs Jacksonville JaguarsSep 28
Tennessee Titans
Last 10: 2-8Streak W115 scored · 26.3 allowed per game2-3 away
- W31-29at Cleveland BrownsDec 7
- L3-25vs Jacksonville JaguarsNov 30
- L24-30vs Seattle SeahawksNov 23
- L13-16vs Houston TexansNov 16
- L20-27vs Los Angeles ChargersNov 2
- L14-38at Indianapolis ColtsOct 26
- L13-31vs New England PatriotsOct 19
- L10-20at Las Vegas RaidersOct 12
- W22-21at Arizona CardinalsOct 5
- L0-26at Houston TexansSep 28
Standings
| Team | Lost | Points against | Points for | Tied | Win % | Won | Overall |
|---|---|---|---|---|---|---|---|
| Jacksonville | 1 | 54 | 60 | 0 | .667 | 2 | 2-1 |
| Tennessee | 1 | 53 | 53 | 0 | .667 | 2 | 2-1 |
| Indianapolis | 2 | 72 | 35 | 1 | .167 | 0 | 0-2-1 |
| Houston | 3 | 65 | 40 | 0 | .000 | 0 | 0-3 |
| Los Angeles | 0 | 30 | 74 | 0 | 1.000 | 3 | 3-0 |
| San Francisco | 1 | 48 | 72 | 0 | .667 | 2 | 2-1 |
| Arizona | 3 | 123 | 108 | 0 | .250 | 1 | 1-3 |
| Seattle | 2 | 45 | 32 | 1 | .167 | 0 | 0-2-1 |
Box score
| Stat | Tennessee Titans | San Francisco 49ers |
|---|---|---|
| First downs | 18 | 28 |
| First downs passing | 8 | 18 |
| First downs rushing | 9 | 7 |
| First downs by penalty | 1 | 3 |
| Third downs | 3-9 | 9-15 |
| Fourth downs | 2-2 | 1-1 |
| Offensive plays | 49 | 70 |
| Total yards | 306 | 430 |
| Yards per play | 6.2 | 6.1 |
| Drives | 9 | 8 |
| Net passing yards | 170 | 292 |
| Completions | 18/29 | 23/30 |
| Yards per pass | 5.9 | 9.1 |
| Interceptions thrown | 0 | 0 |
| Sacks allowed | 0-0 | 2-3 |
| Rushing yards | 136 | 138 |
| Rushing attempts | 20 | 38 |
| Yards per rush | 6.8 | 3.6 |
| Red zone trips | 2-3 | 4-6 |
| Penalties | 7-57 | 6-30 |
| Turnovers | 0 | 1 |
| Fumbles lost | 0 | 1 |
| Defensive touchdowns | 0 | 0 |
| Time of possession | 22:55 | 37:05 |
Win probability
Above the line favours San Francisco 49ers, below favours Tennessee Titans.
Venue
- Levi's StadiumSanta Clara, CA
- Attendance71042
- OfficialsFrank Steratore, Craig Wrolstad, Rich Martinez, Danny Short, Brandon Cruse, Jeff Shears, Brett Bergman
Elsewhere
- NFL depth charts for all 32 teams for 2026 season
- 2026 Fantasy Football Draft Guide: Rankings, mock drafts and analysis
- Fantasy football fast facts: Quick-hit notes to get you ready for your draft
- Mike Clay's Playbook, Part 3: How to manage your team postdraft
- NFL players, coaches, GMs under the most pressure in 2026
- Who calls plays for every NFL team in 2026? What to know