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NFL · Final

Bills Defeat Panthers 29-14 at Highmark Stadium

Saturday, August 15, 2026, 1:00 PM ET · Highmark Stadium

Buffalo Bills 29, Carolina Panthers 14, final. Our NFL picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won Carolina Panthers vs Buffalo Bills?

Buffalo Bills beat Carolina Panthers 29-14 at Highmark Stadium on August 15, 2026.

Who was favored in Carolina Panthers vs Buffalo Bills?

Buffalo Bills were the favorite at DraftKings, moneyline -148 (about 60% implied). The favorite won.

The Buffalo Bills showcased a strong performance at Highmark Stadium, defeating the Carolina Panthers 29-14. This matchup was intriguing as both teams had differing records coming into the game, with the Bills holding a 1-0 record while the Panthers were at 1-1. The Bills have been known for their offensive prowess, averaging 27.4 points per game over their last ten games, while the Panthers have struggled, averaging only 19.0 points in the same span.

In their recent form, the Bills have been impressive, boasting a 7-3 record over their last ten games, with a current winning streak of one. Their last five games have seen them score an average of 28.8 points while allowing 21.2. In contrast, the Panthers have a more balanced record of 5-5 in their last ten games, but they are also on a one-game winning streak. Their average scoring in the last five games stands at 19.4, with an average of 22.6 points allowed.

When considering home and away performance, the Bills have a solid home record of 4-1, while the Panthers have a 2-2 record at home and 3-3 on the road. The Bills’ ability to perform well at home has been a significant factor in their success, as they have consistently outscored opponents in their own stadium.

The teams had previously met in the 2025 season, where the Bills also emerged victorious with a commanding score of 40-9. This history added an extra layer of anticipation to the matchup, as the Bills looked to maintain their dominance over the Panthers.

In terms of injuries, both teams faced challenges. The Bills had several players listed as questionable, including Khalil Shakir, Keon Coleman, and Ty Johnson, while Zane Durant was on injured reserve and Tyrell Shavers was out due to a knee injury. The Panthers also had key players affected, with Jonathon Brooks and Chuba Hubbard listed as questionable, while Brady Christensen and Bam Martin-Scott were on injured reserve, and Taylor Moton was out due to illness. The health of these players could have influenced the game dynamics.

The betting market, as provided by DraftKings, had the Bills favored by 2.5 points, with a total set at 38.5. The odds reflected a belief in the Bills' ability to secure a win, as indicated by their moneyline of -148. The Panthers were listed at +124, highlighting the perceived challenges they faced against the Bills.

Weather conditions at Highmark Stadium were conducive to football, allowing both teams to execute their game plans effectively. The atmosphere was electric, with fans eager to see how their teams would perform in this pivotal matchup.

Viewers were treated to a display of offensive strategy from the Bills, who capitalized on their scoring opportunities, while the Panthers struggled to keep pace. The game highlighted the Bills' ability to dominate on both sides of the ball, showcasing their offensive depth and defensive resilience. Overall, the Bills' victory reinforced their status as a formidable contender in the league.

Odds

BookSpreadTotalMoneyline
DraftKingsBUF -2.5 38.5 o -115 / u -105 Carolina Panthers +124 · Buffalo Bills -148

What these prices pay on $100 · What these numbers mean

Injury report

  • Khalil ShakirQuestionableUndisclosedBuffalo Bills
  • Keon ColemanQuestionableFootBuffalo Bills
  • Ty JohnsonQuestionableLower LegBuffalo Bills
  • Zane DurantInjured ReserveUndisclosedBuffalo Bills
  • Tyrell ShaversOutKnee - ACLBuffalo Bills
  • Jonathon BrooksQuestionableGeneral SorenessCarolina Panthers
  • Brady ChristensenInjured ReserveHamstringCarolina Panthers
  • Chuba HubbardQuestionableHamstringCarolina Panthers
  • Bam Martin-ScottInjured ReserveHamstringCarolina Panthers
  • Taylor MotonOutIllnessCarolina Panthers

Leaders

  • Passing yardsJosh Allen6/8, 111 YDS, 1 TDBuffalo Bills
  • Rushing yardsIan Wheeler7 CAR, 41 YDS, 1 TDBuffalo Bills
  • Receiving yardsDJ Moore3 REC, 61 YDSBuffalo Bills
  • Passing yardsKenny Pickett16/19, 92 YDS, 1 TDCarolina Panthers
  • Rushing yardsAnthony Tyus III4 CAR, 28 YDSCarolina Panthers
  • Receiving yardsAJ Dillon2 REC, 29 YDSCarolina Panthers

Recent form

Buffalo Bills

Last 10: 7-3Streak W127.4 scored · 21.9 allowed per game4-1 at home

  • W35-8vs New York JetsJan 4
  • L12-13vs Philadelphia EaglesDec 28
  • W23-20at Cleveland BrownsDec 21
  • W35-31at New England PatriotsDec 14
  • W39-34vs Cincinnati BengalsDec 7
  • W26-7at Pittsburgh SteelersNov 30
  • L19-23at Houston TexansNov 21
  • W44-32vs Tampa Bay BuccaneersNov 16
  • L13-30at Miami DolphinsNov 9
  • W28-21vs Kansas City ChiefsNov 2

Carolina Panthers

Last 10: 5-5Streak W119 scored · 21.8 allowed per game3-3 away

  • W33-30at Arizona CardinalsAug 7
  • L14-16at Tampa Bay BuccaneersJan 3
  • L10-27vs Seattle SeahawksDec 28
  • W23-20vs Tampa Bay BuccaneersDec 21
  • L17-20at New Orleans SaintsDec 14
  • W31-28vs Los Angeles RamsNov 30
  • L9-20at San Francisco 49ersNov 25
  • W30-27at Atlanta FalconsNov 16
  • L7-17vs New Orleans SaintsNov 9
  • W16-13at Green Bay PackersNov 2

Standings

TeamLostPoints againstPoints forTiedWin %WonOverall
Carolina189970.75033-1
Tampa Bay150400.66722-1
Atlanta145580.66722-1
New Orleans282470.33311-2
Buffalo0488801.00033-0
New England171501.50011-1-1
New York247390.33311-2
Miami363220.00000-3

Box score

StatCarolina PanthersBuffalo Bills
First downs1827
First downs passing1114
First downs rushing310
First downs by penalty43
Third downs3-111-7
Fourth downs2-41-1
Offensive plays5762
Total yards201396
Yards per play3.56.4
Drives89
Net passing yards140245
Completions25/3326/33
Yards per pass3.86.8
Interceptions thrown10
Sacks allowed4-233-24
Rushing yards61151
Rushing attempts2026
Yards per rush3.15.8
Red zone trips2-33-6
Penalties9-789-98
Turnovers10
Fumbles lost00
Defensive touchdowns00
Time of possession26:5633:04

Win probability

Above the line favours Buffalo Bills, below favours Carolina Panthers.

Venue

  • Highmark StadiumOrchard Park, NY
  • Attendance58528
  • OfficialsGreg Meyer, Tab Slaughter, Eugene Hall, John Jenkins, Mark Stewart, Don Willard, Brian Sakowski

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.