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NFL · Final

Patriots Edge Bills in Thrilling NFL Showdown

Sunday, October 4, 2026, 1:00 PM ET · Highmark Stadium

New England Patriots 29, Buffalo Bills 26, final. Our NFL picks are sealed as a hash before kickoff and settled in public, losses included.

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Quick answers

Who won New England Patriots vs Buffalo Bills?

New England Patriots beat Buffalo Bills 29-26 at Highmark Stadium on October 4, 2026.

Who was favored in New England Patriots vs Buffalo Bills?

Buffalo Bills were the favorite at DraftKings, moneyline -345 (about 78% implied). The underdog won.

In a closely contested matchup, the New England Patriots narrowly defeated the Buffalo Bills with a final score of 29-26 at Highmark Stadium. This game showcased the competitive nature of the NFL, particularly between these two storied franchises, and added another chapter to their ongoing rivalry. The Patriots improved their record to 3-2, while the Bills fell to 3-2 in the season.

Both teams entered this game with solid recent form. The Buffalo Bills had a home record of 4-1 and were on a four-game winning streak, averaging 29.0 points scored per game while allowing 21.4. Their last five games reflected a strong performance with an average of 29.6 points scored and 19.8 allowed. In contrast, the New England Patriots, with a 3-2 away record, had a mixed performance recently, losing their last game against the Jacksonville Jaguars 6-35. However, they had previously won three out of their last five games, averaging 23.2 points scored and allowing just 14.2.

The matchup was particularly intriguing given the historical context of their meetings. The teams had split their previous two encounters in the 2025 season, with the Bills winning 35-31 in December and the Patriots winning 23-20 in October. This history added an extra layer of intensity to the game, as both teams sought to assert dominance over their rival.

In terms of injuries, both teams faced challenges. The Bills had several players listed as questionable, including Dee Alford (ankle), Ed Oliver (knee), and Te'Cory Couch (hamstring). DJ Moore was listed as doubtful due to a shoulder injury, and T.J. Sanders was out. The Patriots also had key players dealing with injuries, including Eli Raridon (ankle), Charles Woods (shoulder), and Mack Hollins (calf), all listed as questionable. Behren Morton and Channing Canada were ruled out, with Morton being a coach's decision and Canada sidelined due to a hamstring injury.

The betting market reflected the competitive nature of the game, with DraftKings setting the spread at BUF -7, indicating that the Bills were favored to win by a touchdown. The total points line was set at 49.5, suggesting expectations for a high-scoring affair. The moneyline odds were -345.0 for the Bills and 275.0 for the Patriots, further emphasizing the Bills' status as favorites.

Conditions for the game were typical for early October in Buffalo, with fans braving the elements to support their teams. The atmosphere was electric, with both sets of supporters creating a vibrant backdrop for the clash.

As the game unfolded, viewers were treated to a display of resilience and strategy from both teams. The Patriots managed to capitalize on key opportunities, while the Bills fought hard to maintain their home dominance. The performance of the quarterbacks, along with the effectiveness of the offensive lines, was crucial in determining the outcome of the match. The game served as a reminder of the unpredictability of the NFL, where any team can rise to the occasion and deliver a memorable performance.

What we said beforehand

The Buffalo Bills enter their upcoming matchup against the New England Patriots with an impressive home record of 3-0, while the Patriots struggle with an away record of 1-2. This game, set to take place at Highmark Stadium on October 4, 2026, promises to be a compelling contest as both teams look to solidify their positions in the league.

The Bills have been in formidable form, winning their last five games. Their recent victories include a 31-7 triumph over the Cleveland Browns, a narrow 28-27 win against the Pittsburgh Steelers, and a high-scoring 41-31 win over the Detroit Lions. They also defeated the Houston Texans 36-31 and the Los Angeles Chargers 24-16 in their last outing. This strong streak showcases their offensive capabilities, averaging 29.0 points scored at home and 29.6 points in their last five games, while allowing an average of 21.4 points at home.

In contrast, the New England Patriots have faced challenges in their recent outings, winning only two of their last five games. Their most recent match resulted in a disappointing 35-6 loss to the Jacksonville Jaguars. Prior to that, they managed a 20-3 win against the Pittsburgh Steelers but suffered losses to the Cleveland Browns (37-13) and the Seattle Seahawks (13-10). The Patriots have averaged 26.1 points scored away from home, but their recent performances have seen them struggle defensively, allowing an average of 17.9 points.

Historically, the Bills and Patriots have had a competitive rivalry, with their last two meetings resulting in each team securing a victory. In their most recent encounter on December 14, 2025, the Bills edged out the Patriots with a score of 35-31. Earlier that season, the Patriots defeated the Bills 23-20 at home on October 6, 2025. This history adds an extra layer of intrigue to their upcoming clash.

In terms of injuries, the Bills will be without T.J. Sanders, Christian Benford, Ar'maj Reed-Adams, Jalon Kilgore, and Skyler Bell, all ruled out for the game. The Patriots also face significant challenges, with Behren Morton, Channing Canada, Dametrious Crownover, Christian Gonzalez, and Tanner Arkin all out. The absence of key players on both sides could impact the strategies employed by each team.

The betting market currently favors the Bills, with DraftKings listing them as 7-point favorites. The total points line is set at 49.5, indicating expectations for a potentially high-scoring affair. The Bills' strong home record and recent form have contributed to their status as favorites.

Weather conditions are expected to be favorable for the matchup, with a temperature of 68°F and sunny skies. Wind gusts may reach 11 mph, but overall, the weather should not significantly affect gameplay.

As viewers tune in, they should watch for the performance of Bills quarterback Josh Allen, who has thrown for 786 yards, five touchdowns, and two interceptions this season. His ability to connect with receiver Dalton Kincaid, who has 263 receiving yards and one touchdown, will be crucial. For the Patriots, quarterback Drake Maye has struggled with six interceptions this season, and his performance will be pivotal in determining the outcome of the game. Rhamondre Stevenson leads the rushing attack for New England with 116 yards, while Mack Hollins has been a key target in the passing game with 156 receiving yards.

This matchup between the Bills and Patriots is set to be an exciting encounter, with both teams looking to assert their dominance in the league.

Odds

BookSpreadTotalMoneyline
DraftKingsBUF -7 49.5 o -108 / u -112 New England Patriots +275 · Buffalo Bills -345

What these prices pay on $100 · What these numbers mean

Injury report

  • Dee AlfordQuestionableAnkleBuffalo Bills
  • Ed OliverQuestionableKneeBuffalo Bills
  • Te'Cory CouchQuestionableHamstringBuffalo Bills
  • DJ MooreDoubtfulShoulderBuffalo Bills
  • T.J. SandersOutBuffalo Bills
  • Eli RaridonQuestionableAnkleNew England Patriots
  • Charles WoodsQuestionableShoulderNew England Patriots
  • Mack HollinsQuestionableCalfNew England Patriots
  • Behren MortonOutCoach's DecisionNew England Patriots
  • Channing CanadaOutHamstringNew England Patriots

Leaders

  • Passing yardsJosh Allen23/33, 253 YDS, 1 TD, 1 INTBuffalo Bills
  • Rushing yardsJames Cook III12 CAR, 75 YDS, 1 TDBuffalo Bills
  • Receiving yardsKeon Coleman6 REC, 116 YDS, 1 TDBuffalo Bills
  • Passing yardsDrake Maye22/37, 269 YDS, 3 TD, 1 INTNew England Patriots
  • Rushing yardsDrake Maye8 CAR, 54 YDSNew England Patriots
  • Receiving yardsHunter Henry5 REC, 62 YDSNew England Patriots

Recent form

Buffalo Bills

Last 10: 8-2Streak W429 scored · 21.4 allowed per game4-1 at home

  • W24-16vs Los Angeles ChargersSep 27
  • W41-31vs Detroit LionsSep 18
  • W36-31at Houston TexansSep 13
  • W35-8vs New York JetsJan 4
  • L12-13vs Philadelphia EaglesDec 28
  • W23-20at Cleveland BrownsDec 21
  • W35-31at New England PatriotsDec 14
  • W39-34vs Cincinnati BengalsDec 7
  • W26-7at Pittsburgh SteelersNov 30
  • L19-23at Houston TexansNov 21

New England Patriots

Last 10: 7-3Streak L126.1 scored · 17.9 allowed per game3-2 away

  • L6-35at Jacksonville JaguarsSep 27
  • W20-3vs Pittsburgh SteelersSep 20
  • L10-13at Seattle SeahawksSep 10
  • W38-10vs Miami DolphinsJan 4
  • W42-10at New York JetsDec 28
  • W28-24at Baltimore RavensDec 22
  • L31-35vs Buffalo BillsDec 14
  • W33-15vs New York GiantsDec 2
  • W26-20at Cincinnati BengalsNov 23
  • W27-14vs New York JetsNov 14

Standings

TeamLostPoints againstPoints forTiedWin %WonOverall
Buffalo11071270.75033-1
New England277650.50022-2
New York384760.25011-3
Miami386360.00000-3

Box score

StatNew England PatriotsBuffalo Bills
First downs2619
First downs passing159
First downs rushing106
First downs by penalty14
Third downs5-126-12
Fourth downs2-21-1
Offensive plays7354
Total yards405340
Yards per play5.56.3
Drives1211
Net passing yards262249
Completions22/3723/33
Yards per pass6.97.3
Interceptions thrown11
Sacks allowed1-71-4
Rushing yards14391
Rushing attempts3520
Yards per rush4.14.6
Red zone trips3-32-4
Penalties6-355-31
Turnovers22
Fumbles lost11
Defensive touchdowns00
Time of possession33:4126:19

Win probability

Above the line favours Buffalo Bills, below favours New England Patriots.

Venue

  • Highmark StadiumOrchard Park, NY
  • Attendance60606
  • OfficialsBill Vinovich, Jimmy Buchanan, Todd Prukop, Aaron Santi, Brian Bolinger, Frank LeBlanc, Scott Campbell

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Fixture data from the league feeds. The report was written from the recorded facts for this game and nothing else.