Ole Miss Rebels vs Oklahoma Sooners prediction & odds

The upcoming clash between the Oklahoma Sooners and the Ole Miss Rebels promises to be an intriguing matchup as both teams look to solidify their standings in the NCAAF landscape. The game is set to take place at Memorial Stadium in Norman, Oklahoma, on November 15, 2026, with kickoff scheduled for 18:00 UTC.

Oklahoma has shown a mixed bag of results in its last five games, recording three wins and two losses. Their recent performances include a victory against the Florida Gators, where they won 23-7, and a notable win against the Texas Longhorns, ending that game at 27-24. However, they also suffered defeats against the South Carolina Gamecocks (25-42) and the Kentucky Wildcats (13-21). The Sooners have averaged 22.2 points scored and allowed 21.8 points in their last five games. At home, they have a record of 4-2, averaging 21.6 points scored and 18.6 points allowed over their last ten games.

On the other hand, Ole Miss has had a more favorable recent run with a record of 7-3 over their last ten games, although they are currently on a one-game losing streak. Their last outing ended in a heavy defeat against the Georgia Bulldogs, where they lost 7-42. Prior to that, they secured convincing wins against teams like Auburn (45-15) and Missouri (31-3). The Rebels have averaged 34.2 points scored and 25.3 points allowed in their recent games. They have performed well at home with a record of 5-1 but have struggled slightly on the road with a 2-2 record.

In their previous meeting on October 25, 2025, Ole Miss emerged victorious against Oklahoma, winning the game 34-26. This history could add an extra layer of intensity as the Sooners look to avenge that loss on their home turf.

In terms of key players, Oklahoma's John Mateer leads the team in passing yards with 2,042 yards, having thrown for 15 touchdowns and 7 interceptions. Lloyd Avant has contributed in the rushing department with 394 yards and 2 touchdowns, while Isaiah Sategna III has been a reliable target in the receiving game, amassing 625 yards and 4 touchdowns. Ole Miss counters with Trinidad Chambliss, who has thrown for 2,359 yards, 18 touchdowns, and 9 interceptions. Kewan Lacy has been effective in the ground game with 388 rushing yards and 5 touchdowns, and Deuce Alexander leads the receiving corps with 669 yards and 5 touchdowns.

The betting market, as provided by DraftKings, has Oklahoma favored by 2.5 points with a total set at 48.5. The moneyline for the Sooners is -142, while the Rebels are at +120.

Weather conditions for the game are expected to be cool, with a temperature around 42°F, a 49% chance of precipitation, and wind gusts reaching 18 mph. These factors could influence the style of play and overall scoring.

As the game approaches, viewers should keep an eye on the performance of both quarterbacks, the effectiveness of the rushing attacks, and how each defense responds to the opposing offense. The outcome could hinge on which team can better execute their game plan and capitalize on scoring opportunities.